Coating with Hypertonic Saline Improves Virus Protection of Filtering Facepiece Manyfold—Benefit of Salt Impregnation in Times of PandemicBrief Report Published on 2021-07-112022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] aerosol alphacoronavirus alphacoronavirus 1 cell line coating Concentration Contagion COVID-19 COVID-19 pandemic defined doffing donning exceeded growth medium hypertonic hypertonic saline Infection infection rate initial investigated lack Mask Masks medium pathogen phosphate-buffered saline PROTECT protection protective effect reduce reduced saccharose Saline salt SARS-CoV-2 Spread surgical TGEV time transmissible gastroenteritis virus treated Viral load Viral particles was used [DOI] 10.3390/ijerph18147406 PMC 바로가기 [Article Type] Brief Report
Age differences in the association of comorbid burden with adverse outcomes in SARS-CoV-2Research Published on 2021-07-062022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] adjusted Admission Adults adverse outcome Affair age association calculated Care CCI Charlson Comorbidity Index Clinical management Cohort Comorbidity cumulative death Department diagnostic distribution exceeded Health Hospitalization hospitalized patient ICU ICU admission incidence intensive care interactions interquartile range limitation longitudinal cohort study measurement mechanical ventilation objective Older Older age outcome pandemic participant Patient positive prognostic quartile ranged Result risk SARS-CoV-2 SARS-CoV-2 test supplementary material System tested threshold vaccination veteran [DOI] 10.1186/s12877-021-02340-5 PMC 바로가기 [Article Type] Research
Age differences in the association of comorbid burden with adverse outcomes in SARS-CoV-2Research Published on 2021-07-062022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, SARS, [키워드] adjusted Admission Adults adverse outcome Affair age association calculated Care CCI Charlson Comorbidity Index Clinical management Cohort Comorbidity cumulative death Department diagnostic distribution exceeded Health Hospitalization hospitalized patient ICU ICU admission incidence intensive care interactions interquartile range limitation longitudinal cohort study measurement mechanical ventilation objective Older Older age outcome pandemic participant Patient positive prognostic quartile ranged Result risk SARS-CoV-2 SARS-CoV-2 test supplementary material System tested threshold vaccination veteran [DOI] 10.1186/s12877-021-02340-5 PMC 바로가기 [Article Type] Research
Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in WuhanArticle Published on 2021-07-062022-10-04 Journal: Nature Communications [Category] SARS, 임상, 치료기술, 치료법, [키워드] acute respiratory syndrome Adaptive immunity age antibodies antibody Antibody Response Antibody titer Antimicrobial responses convalescent convalescent COVID-19 patient convalescent plasma coronavirus coronavirus disease COVID-19 COVID-19 pandemic decrease Diagnosis domain Donor exceeded facilitate female Health humoral immune response IgG antibody IgG response immune memory Immunity initial male Neutralizing antibody titer older patient patients plasma plasma sample positive correlation positive rate promote reduce responses risk SARS-CoV-2 Spike protein the patient therapy Vaccine viral infection Wuhan Wuhan, China [DOI] 10.1038/s41467-021-24230-5 PMC 바로가기 [Article Type] Article
Epidemiological Study of COVID-19 Fatalities and Vaccine Uptake: Insight From a Public Health Database in Ontario, CanadaAllergy/Immunology Published on 2021-07-042022-10-31 Journal: Cureus [Category] COVID-19, [키워드] addition adjusted age age and gender all age group Canada Case fatality rate CFR CFRs Community COVID 19 COVID-19 COVID-19 mortality death decrease Demographic factors disease distribution Elderly population event exceeded fatality Gender groups highest insight less National occurred Odds ratio per day populations Public reached receiving reported Research responsible rural areas Statistics Canada the vaccine urban area used data vaccination rate Vaccine vaccine science and policy was reduced women [DOI] 10.7759/cureus.16160 PMC 바로가기 [Article Type] Allergy/Immunology
Exponential increase in neutralizing and spike specific antibodies following vaccination of COVID-19 convalescent plasma donorsCOVID-19 회복기 혈장 기증자 백신 접종 후 중화 및 스파이크 특이적 항체의 기하급수적인 증가Article Published on 2021-07-012022-09-12 Journal: Transfusion [Category] MERS, SARS, 진단, [키워드] antibody approval candidate CCP chemiluminescence immunoassay convalescent plasma COVID-19 COVID-19 infection COVID-19 vaccines demonstrated DiaSorin Donor dramatic increase exceeded IC50 immunology immunology (other than RBC serology) increase in Infection Neutralizing neutralizing antibody Neutralizing antibody titer plaque reduction neutralization positive Practice PRNT RBC recovered recovered COVID-19 patient screened significantly significantly higher single vaccination specific antibody Spike-specific antibody subject tested transfusion practices (adult). vaccination with COVID-19 [DOI] 10.1111/trf.16401 PMC 바로가기 [Article Type] Article
Safety and effectiveness concerns of lopinavir/ritonavir in COVID-19 affected patients: a retrospective seriesCOVID-19 영향을 받는 환자에서 로피나비르/리토나비르의 안전성 및 유효성 문제: 후향적 시리즈Article Published on 2021-07-012022-09-11 Journal: Clinical toxicology (Philadelphia, Pa.) [Category] SARS, 치료제, [키워드] addition affected Antiviral Case series case sery cholestasis Combination Concentration coronavirus disease COVID-19 COVID-19 patient COVID-19 patients dyslipidemia EC50 Effect Effectiveness electrolyte imbalance Elevation exceeded Gastrointestinal symptom gastrointestinal symptoms greater HIV HIV patients Human immunodeficiency virus hyponatremia immunodeficiency virus In-vitro liver enzyme Lopinavir Lopinavir/ritonavir LPV Novel coronavirus novel coronavirus disease occur overdose Patient raise raising reached retrospective Ritonavir Safety safety profile SARS-CoV-2 side Side effect Side effects therapeutic threshold thresholds Toxicity Treatment Triglyceride [DOI] 10.1080/15563650.2020.1842882 PMC 바로가기 [Article Type] Article
Early Humoral Responses of Hemodialysis Patients after COVID-19 Vaccination with BNT162b2BNT162b2로 COVID-19 백신 접종 후 혈액 투석 환자의 초기 체액 반응Article Published on 2021-07-012022-09-11 Journal: Clinical journal of the American Society of Nephro [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody Response Antibody responses BNT162b2 coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 develop dialysis exceeded first dose greater healthy control healthy controls Hemodialysis high risk humoral Humoral response IgG Infection interquartile range majority median mRNA vaccine neutralization Neutralizing antibodies neutralizing antibody nine Participants Patient positive receiving Receptor binding reduced respiratory response S1 domain SARS-CoV-2 SARS-CoV2 second dose sensitivity severe coronavirus disease single-center study Spike protein the spike protein threshold university vaccination Vaccine vaccine dose Viral viral neutralization [DOI] 10.2215/CJN.03700321 PMC 바로가기 [Article Type] Article
Benefits and risks associated with different uses of the COVID-19 vaccine Vaxzevria: a modelling study, France, May to September 2021Rapid Communication Published on 2021-07-012022-10-31 Journal: Eurosurveillance [Category] COVID-19, SARS, [키워드] Adults adverse event AstraZeneca benefit benefit-risk balance COVID-19 COVID-19 vaccination COVID-19 vaccine distribution European exceeded France French hospitalisation magnitude Older risk risk of death SARS-CoV-2 thrombosis Vaccine Vaxzevria [DOI] 10.2807/1560-7917.ES.2021.26.26.2100533 PMC 바로가기 [Article Type] Rapid Communication
COVID-19 mRNA vaccine induced antibody responses against three SARS-CoV-2 variantsCOVID-19 mRNA 백신 유도된 3가지 SARS-CoV-2 변이체에 대한 항체 반응Observational Study Published on 2021-06-282022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 임상, 진단, [키워드] Affect antibodies Antibody Response B.1.1.7 B.1.1.7 variant B.1.351 B.1.351 variant BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine BNT162b2 vaccine circulating circulating SARS-CoV-2 variants Clinical use COVID-19 COVID-19 patients COVID-19 vaccine cross-neutralization D614G substitution Efficacy Evidence exceeded Health care Health care worker health care workers induce mRNA vaccine Mutation neutralization neutralize Neutralizing antibodies neutralizing antibody not affected protective immunity provide raised Re-infection reduced reduction RNA vaccines SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV2 second dose sera seronegative vaccinee seronegative vaccinees show specific neutralizing antibodies Spike protein the SARS-CoV-2 the spike protein titre Vaccine vaccine candidate vaccine candidates vaccine efficacy variant [DOI] 10.1038/s41467-021-24285-4 PMC 바로가기 [Article Type] Observational Study