Exosomes from COVID-19 Patients Carry Tenascin-C and Fibrinogen-β in Triggering Inflammatory Signals in Cells of Distant OrganArticle Published on 2021-03-202022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] Analysis approach carried CCL5 Cell chemokine controls COVID-19 COVID-19 patient COVID-19 patients Cytokine storm Cytokines Distant examined Exosome Exosomes expression FGB fibrinogen-β healthy healthy subjects healthy volunteer hepatocyte IL-6 Immunity infected cell interleukin-6 Ligand mass spectrometry motif NF-κB organ overshoot Pathogenesis pathway plasma pro-inflammatory cytokine proteomic SARS-COV-2 infection signal Signaling significant increase stimulate tenascin-C tissue damage TNC TNF-α transported tumor necrosis factor-α [DOI] 10.3390/ijms22063184 PMC 바로가기 [Article Type] Article
[Differential proteomic screening of plasma exosomes before and after magnesium isoglycyrrhizinate treatment in chronic hepatitis B]Article Published on 2021-03-202023-06-12 Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese [Category] B형 간염, [키워드] Chronic Hepatitis B Exosome Magnesium isoglycyrrhizinate plasma proteomics [DOI] 10.3760/cma.j.cn501113-20200222-00062
Release mechanisms of major DAMPs주요 DAMP의 방출 메커니즘Review Published on 2021-03-132022-08-07 Journal: Apoptosis [Category] Biochemistry, [키워드] Activation addition anti-DAMP strategies Apoptosis ATP Cancer Cell cell death cell membrane cell-free DNA channel pores contribute Damage-associated molecular patterns DAMP DAMP release DAMP-specific mechanism DAMPs disorder disorders ectosomes effective endogenous molecule endogenous molecules Exocytosis Exosome Exosomes Extracellular extracellular cold-inducible RNA-binding protein extracellular RNA extracellular RNAs Ferroptosis focus foment heat shock proteins Histones Inflammation inflammatory mediator Inflammatory mediators live cell live cells Lysosomes mechanism mechanisms of release mediators membrane rupture molecular pattern necroptosis Necrosis NETosis Other Protein pyroptosis Release released reported secretory lysosome secretory lysosomes Sepsis tissues [DOI] 10.1007/s10495-021-01663-3 PMC 바로가기 [Article Type] Review
Mesenchymal Stem Cell-Derived Exosomes Exhibit Promising Potential for Treating SARS-CoV-2-Infected PatientsReview Published on 2021-03-072022-10-31 Journal: Cells [Category] COVID-19, [키워드] Anti-inflammatory assist Cell clinical trial clinicians and researcher co-morbidity COVID-19 COVID-19 infection COVID-19 pandemic disease effort Exosome Exosomes Extracellular vesicles Health immunomodulatory property IMPROVE knowledge lockdown management mechanical ventilator Mesenchymal stem cells Novel coronavirus outcome pandemic patients Pneumonia Potential researchers responsible SARS-CoV-2 SARS-CoV-2-infected patients STEM stem cell therapeutic regime therapy threat treat treating treatment for COVID-19 World War II [DOI] 10.3390/cells10030587 PMC 바로가기 [Article Type] Review
Mesenchymal stem cell alongside exosomes as a novel cell-based therapy for COVID-19: A review studyReview Article Published on 2021-03-062023-07-01 Journal: Clinical immunology (Orlando, Fla.) [Category] SARS, [키워드] AAT, Alpha-1-anti trypsin ACE2, angiotensin-converting enzyme 2 ARDS, acute respiratory distress syndrome Coronavirus disease 2019 COVID-19, Coronavirus disease 2019 CXCL10, C-X-C motif chemokine ligand 10 DCs, dendritic cells Exosome HGF, Hepatocyte Growth Factor HLA, human leukocyte antigen IL-1RA, interleukin-1 receptor antagonist KGF, Keratinocyte growth factor MCP1, monocyte chemoattractant protein 1 MERS-CoV, Middle East respiratory syndrome coronavirus mesenchymal stem cell MIP1α, Macrophage inflammatory protein 1α MMP, matrix-metalloprotein MSC, mesenchymal stem cell RAS, The Renin-Angiotensin system SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 TGF, Transforming growth factor TMPRSS2, Transmembrane protease/serine2 TNF, Tumor Necrosis Factor Treatment VE, Vascular endothelial VGEF, Vascular endothelial growth factor [DOI] 10.1016/j.clim.2021.108712 PMC 바로가기 [Article Type] Review Article
Exosome in Hepatocellular Carcinoma: an updateReview Published on 2021-03-052023-08-30 Journal: Journal of Cancer [Category] E형 간염, [키워드] biological function Biomarker Exosome Hepatocellular carcinoma therapeutic target [DOI] 10.7150/jca.54566 PMC 바로가기 [Article Type] Review
Emerging role and therapeutic application of exosome in hepatitis virus infection and associated diseasesReview Published on 2021-03-042023-08-30 Journal: Journal of Gastroenterology [Category] E형 간염, [키워드] Exosomal nanoshuttle Exosome Hepatitis virus Immune escape immune response [DOI] 10.1007/s00535-021-01765-4 PMC 바로가기 [Article Type] Review
Interferon-Induced Macrophage-Derived Exosomes Mediate Antiviral Activity Against Hepatitis B Virus Through miR-574-5pArticle Published on 2021-02-242023-06-13 Journal: The Journal of Infectious Diseases [Category] B형 간염, [키워드] Exosome HBV cccDNA hsa-miR-574-5p IFN-α pgRNA [DOI] 10.1093/infdis/jiaa399
Circulating Exosomes Are Strongly Involved in SARS-CoV-2 InfectionMolecular Biosciences Published on 2021-02-222022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] Activation addition Analysis approach AUC Biomarker Biomarkers C1r circulating Coagulation complement complement pathways component Course COVID-19 pathogenesis diagnostic Disease progression disease severity Exosome extracellular vesicle fibrinogen Host host cell host response host-response immune response Infection Inflammation investigated involved main mechanism modulate novel coronavirus SARS-CoV-2 organ dysfunctions plasma plasma exosomes presenting proteomic proteomics SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA serum amyloid shown Spread Therapeutic strategies tissue damage viral infection virus [DOI] 10.3389/fmolb.2021.632290 PMC 바로가기 [Article Type] Molecular Biosciences
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations코로나19 이후 합병증 및 신경학적 징후의 특성화 및 바이오마커 분석Article Published on 2021-02-132022-09-11 Journal: Cells [Category] MERS, 바이오마커, 진단, [키워드] age All participants amyloid beta analyses antibody characterization co-morbidity collected Comorbidities Complication controls CoV COVID-19 COVID-19 infection cytokine Cytokines demonstrated dysfunction Exosome explain Extracellular had more IL-4 IL6 individual Infection initial Longitudinal studies longitudinal study manifestation marker MONITOR morbidity nCoV neurodegeneration neurogranin Neuroinflammation neurologic neurological neurological problem neurological problems Neurological symptom Neurological symptoms neuronal pandemic participant Participants plasma plasma biomarker Plasma cytokine positive correlation Protein Proteins recovering from COVID-19 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 pandemic Severe infection severity significantly increased systemic effects the SARS-CoV-2 Vesicle volunteers was increased [DOI] 10.3390/cells10020386 PMC 바로가기 [Article Type] Article