Prothrombotic immune thrombocytopenia after COVID-19 vaccination코로나19 예방접종 후 혈전성 면역 혈소판 감소증Case Reports Published on 2021-07-292022-09-12 Journal: Blood [Category] SARS, 진단, [키워드] acute respiratory syndrome antibodies binding anticoagulation Autoimmune AZD1222 buffer ChAdOx1 vaccine characterized clinical experience clinical manifestation Combination coronavirus COVID-19 vaccination D-dimer demonstrated described disorder elevated first vaccination healthy donor Immune thrombocytopenia Intravenous immunoglobulin pathology Patient patient sera patients PF4 Platelet prothrombotic resolved risk SARS-CoV-2 suppressed Thromboembolic event Thromboembolic events Thromboembolism thrombosis thrombotic Two patient vaccination venous [DOI] 10.1182/blood.2021011958 PMC 바로가기 [Article Type] Case Reports
Post-Vaccination Anti-SARS-CoV-2-Antibody Response in Patients with Multiple Myeloma Correlates with Low CD19+ B-Lymphocyte Count and Anti-CD38 TreatmentArticle Published on 2021-07-282022-10-31 Journal: Cancers [Category] COVID-19, [키워드] age Anti-SARS-CoV-2 antibody response anti-SARS-CoV-2 vaccination anti-SARS-CoV-2 vaccine anti-SARS-CoV-2 vaccines anti-SARS-CoV-2-antibody Antibody titer Antibody titers B lymphocyte booster vaccination CD19+ Cell clinical factor correlated count COVID-19 pandemic current therapy cut-off value disease dyscrasia Efficacy first dose first vaccination Hematological malignancies immunomodulatory drug Linear regression majority mRNA Multiple Multiple myeloma multivariable Myeloma Patient patients plasma positive receiving reduced respond poorly response SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccination SARS-CoV-2 vaccine significantly significantly higher simple single-center study Treatment Vaccines [DOI] 10.3390/cancers13153800 PMC 바로가기 [Article Type] Article
Acquired thrombotic thrombocytopenic purpura after first vaccination dose of BNT162b2 mRNA COVID-19 vaccineBNT162B2 mRNA covid-19 백신의 첫 번째 백신 접종 용량 후 획득 된 혈전 혈소판 감소 성 푸 푸라.Case Reports Published on 2021-07-262022-09-10 Journal: Annals of Hematology [Category] MERS, SARS, 바이오마커, [키워드] Acquired COVID-19 vaccine dose first vaccination mRNA of BNT162b2 purpura thrombotic [DOI] 10.1007/s00277-021-04584-y PMC 바로가기 [Article Type] Case Reports
Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals혈청 양성 및 혈청 형성 개인에서 SARS-CoV-2 mRNA 백신 투여 동안 체액 면역 반응Research Article Published on 2021-07-262022-09-01 Journal: BMC Medicine [Category] SARS, 진단, [키워드] administration antibody antibody level antibody levels Antibody Response Antibody responses Antibody titers approved binding Binding assays BNT162b2 caused comparable coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated dose doses Efficacy epitope Epitopes first vaccination global pandemic guide had no high resolution humoral immune responses IgA IgG IgM antibody immune immune response immune responses immunization immunodominant individual Infection mapped Messenger RNA mRNA mRNA vaccine peptide peptides Pfizer-BioNTech protein antigen regimens Result S1 and S2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibody SARS-CoV-2 spike SARS-CoV-2 spike protein SARS-CoV-2 vaccine SARS-CoV-2 viral SARS-CoV-2 virus seronegative seropositive seropositive individual seropositive individuals significantly higher single dose specificity Spike protein subunit supplementary material Support the antibody response the SARS-CoV-2 the SARS-CoV-2 virus USA vaccination Vaccine Viral viral infection while [DOI] 10.1186/s12916-021-02055-9 PMC 바로가기 [Article Type] Research Article
Impaired Immune Response to SARS-CoV-2 Vaccination in Dialysis Patients and in Kidney Transplant RecipientsMulticenter Study Published on 2021-07-132022-10-05 Journal: Kidney360 [Category] SARS, 임상, [키워드] Against age Analysis Antibody Response BNT162b2 chronic clinical clinical immunology cohort study Control controls COVID-19 COVID-19 mRNA vaccine Cutoff dialysis dose evaluated first vaccination high risk humoral humoral immune response IgG level immune immune response Immunity Impaired kidney Kidney failure kidney transplant recipient Kidney transplantation Modification MOST mRNA-1273 neutralization capacity neutralizing antibody Neutralizing antibody titer Patient Prophylaxis recipient renal renal insufficiency response SARS-CoV-2 SARS-CoV-2 specific antibody SARS-CoV-2 vaccination SARS-CoV-2-specific antibody SARS-CoV-2-specific IgG second vaccination Severe COVID-19 Infection significantly significantly lower Transplant transplantation undetectable vaccination Vaccination strategy Vaccine Virology were measured [DOI] 10.34067/KID.0003512021 PMC 바로가기 [Article Type] Multicenter Study
Single-dose BNT162b2 mRNA COVID-19 vaccine significantly boosts neutralizing antibody response in health care workers recovering from asymptomatic or mild natural SARS-CoV-2 infection단일 용량 BNT162b2 mRNA COVID-19 백신은 무증상 또는 경증의 자연적 SARS-CoV-2 감염에서 회복하는 의료 종사자의 중화 항체 반응을 크게 향상시킵니다Article Published on 2021-07-012022-09-12 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, [키워드] analyses Antibody Response Asymptomatic asymptomatic infection BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine boost Complete correlation COVID-19 COVID-19 vaccine Diagnosis dose evaluated first dose first vaccination Health care Health care worker health care workers Humoral immunity Infection interquartile range Live virus median microneutralization Mild mRNA Neutralizing antibody response of BNT162b2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibody significant increase significantly significantly higher single vaccination Single-dose subjects titre uninfected vaccine dose virus replication [DOI] 10.1016/j.ijid.2021.05.033 PMC 바로가기 [Article Type] Article
Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study암 환자를 위한 COVID-19 백신 BNT162b2의 1회 투여 대 2회 투여의 안전성 및 면역원성: 전향적 관찰 연구의 중간 분석Observational Study Published on 2021-06-012022-09-10 Journal: The Lancet. Oncology [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] 95% CI Administered All participant All participants analysed analyses anti-S IgG antibody available data Blood blood sample Blood samples BNT162b2 BNT162b2 vaccine boost Cancer Cancer Research UK Cohort college COVID-19 COVID-19 vaccine Data analysis death dose Efficacy Efficacy and safety eight Endpoint enrolled Evidence evidence of exclusion finding first dose first vaccination FIVE Follow-up Francis Crick funding Haematological cancer Health and Care Research Wales Health Research Authority health-care healthy control healthy controls healthy controls; hospital immunogenicity immunogenicity analysis injection Injection-site pain interim analysis intramuscularly King local reaction London nasopharyngeal NHS observational study of BNT162b2 Pain participant Patient Patients with cancer patients with haematological Pfizer–BioNTech positive profile proportion prospective observational study Protein real-time RT-PCR REC receive recruited Registered reported rRT-PCR Safety SARS-CoV-2 SARS-CoV-2 spike second dose Seroconversion seropositive significantly single vaccine solid cancer Support Swab test symptomatic symptomatic COVID-19 the patient titre toxicities Toxicity Trust vaccination Vaccine Wellcome Trust [DOI] 10.1016/S1470-2045(21)00213-8 PMC 바로가기 [Article Type] Observational Study
First case of postmortem study in a patient vaccinated against SARS-CoV-2SARS-CoV-2 예방 접종을 받은 환자의 부검 첫 사례Case Reports Published on 2021-06-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료법, [키워드] assigned Autopsy BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine bronchopneumonia cause of death cerebrum Chain Reaction characteristic COVID-19 COVID-19 vaccine Cycle threshold value Cycle threshold values death died elicited examined except for first dose first vaccination heart histology Immunity immunogenicity Immunoglobulin induce kidney liver Lungs molecular morphological feature mucosa nucleocapsid nucleocapsid IgG observé olfactory olfactory bulb organ oropharynx Patient polymerase chain polymerase chain reaction positive Postmortem Protein real-time polymerase chain reaction renal Respiratory failure RT-PCR SARS-CoV-2 significant level spike Spike protein Symptoms tested Trachea Vaccine [DOI] 10.1016/j.ijid.2021.04.053 PMC 바로가기 [Article Type] Case Reports
Response to first vaccination against SARS-CoV-2 in patients with multiple myeloma다발성 골수종 환자에서 SARS-CoV-2에 대한 첫 번째 예방 접종에 대한 반응Article Published on 2021-06-012022-09-12 Journal: The Lancet. Haematology [Category] MERS, SARS, 진단, [키워드] first vaccination Multiple myeloma Patient response SARS-CoV-2 [DOI] 10.1016/S2352-3026(21)00110-1 PMC 바로가기 [Article Type] Article
Low titers of SARS-CoV-2 neutralizing antibodies after first vaccination dose in cancer patients receiving checkpoint inhibitors체크포인트 억제제를 투여받는 암 환자에서 첫 접종 후 낮은 역가의 SARS-CoV-2 중화항체Letter to the Editor Published on 2021-05-312022-09-12 Journal: Journal of Hematology & Oncology [Category] SARS, 진단, [키워드] AZD1222 BNT162b2 Cancer cancer patient Cohort dose Efficacy first dose first vaccination General population healthy volunteer Hematological malignancies Hematological malignancy Immune checkpoint inhibitors Infection inhibitor initial initiated Neutralizing antibodies Patient Patients with cancer provide receiving SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccination significantly lower supplementary material systemic therapy the patient Therapies therapy Treatment vaccination [DOI] 10.1186/s13045-021-01099-x PMC 바로가기 [Article Type] Letter to the Editor