Severe acute respiratory syndrome coronavirus 2 prevalence in saliva and gastric and intestinal fluid in patients undergoing gastrointestinal endoscopy in coronavirus disease 2019 endemic areas: Prospective cross‐sectional study in Japan중증급성호흡기증후군 코로나바이러스 2 코로나바이러스 질환 2019 풍토병 지역에서 위장관 내시경을 받는 환자의 타액 및 위 및 장액 유병률: 일본의 전향적 횡단면 연구Original Article Published on 2021-03-122022-09-11 Journal: Digestive Endoscopy [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age analyzed antibody Antibody test Chain Reaction city coronavirus coronavirus disease Coronavirus disease 2019 COVID‐19 COVID‐19 detectable Early detection Endemic endoscope endoscopy fluids Gastrointestinal gastrointestinal fluid gastrointestinal tract Infection information intestinal Japan medical staff medication no significant differences objective pandemic era Patient patients PCR PCR positive polymerase chain reaction positive positive rate positive result Prevalence Primary outcome Prospective provided Registered respiratory Result Saliva saliva samples SARS‐CoV‐2 SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus Sex significant difference tested Treatment university virus was collected Yokohama [DOI] 10.1111/den.13945 PMC 바로가기 [Article Type] Original Article
Towards a sensitive and accurate interpretation of molecular testing for SARS-CoV-2: a rapid review of 264 studiesSARS-CoV-2에 대한 분자 테스트의 민감하고 정확한 해석을 위해: 264개 연구에 대한 신속한 검토Review Published on 2021-03-112022-09-12 Journal: Eurosurveillance [Category] 진단, [키워드] Blood cerebrospinal fluid children Clinical practice clinical samples collected Combination Contact tracing COVID-19 COVID-19 cases COVID-19 diagnosis dataset diagnostics gastrointestinal tract immunocompromised individuals infancy Infection Interpretation Isolation key factor knowledge Laboratory laboratory diagnosis molecular observation outbreak outlined pandemic performed polymerase chain reaction Pregnancy provided public health response Result RNA SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection Semen sensitive specimen [DOI] 10.2807/1560-7917.ES.2021.26.10.2001134 PMC 바로가기 [Article Type] Review
SARS-CoV-2 Infection and Disease Modelling Using Stem Cell Technology and Organoids줄기 세포 기술 및 오르가노이드를 사용한 SARS-CoV-2 감염 및 질병 모델링Review Published on 2021-02-262022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, 진단, [키워드] ACE2 airway epithelial cells alveolar Apoptosis cardiovascular system Cell cell damage cells Central nervous system Choroid plexus Clinical studies clinical study colonic contribute demonstrated Direct disease Endothelial cell endothelial cells Enterocyte enterocytes epithelial epithelial cells gastrointestinal tract highlighting human host Hypothesis immunological impairing in vitro model indirect effect indirect effects infect infected individuals Inflammation innate immune response intestinal organoid lung lung alveolar lung epithelia mechanism Neurological symptom Neurological symptoms Neuron neurons Organoid organoids organs Pathogenesis pathogenesis of SARS-CoV-2 replicate review SARS-CoV-2 SARS-CoV-2 cell SARS-COV-2 infection SARS-CoV-2 pathogenesis STEM stem cell surfactant susceptible systemic inflammatory target technology Trigger triggers tropism type I variance Vascular damage Viral viral damage viral infection virus [DOI] 10.3390/ijms22052356 PMC 바로가기 [Article Type] Review
Gastrointestinal mucosal damage in patients with COVID-19 undergoing endoscopy: an international multicentre studyMulticenter Study Published on 2021-02-242023-06-16 Journal: BMJ open gastroenterology [Category] MERS, [키워드] COVID-19 endoscopy gastrointestinal tract mucosal infection [DOI] 10.1136/bmjgast-2020-000578 PMC 바로가기 [Article Type] Multicenter Study
Microbiota Modulation of the Gut-Lung Axis in COVID-19COVID-19에서 장폐 축의 미생물총 조절Review Published on 2021-02-242022-09-11 Journal: Frontiers in Immunology [Category] MERS, 치료기술, 치료제, [키워드] addition administration Affect affected Anti-inflammatory axis bidirectional caused condition consequence correlated COVID-19 COVID-19 patients deaths deregulation diarrhea digestive Diversity duodenum Dysbiosis exacerbated Fecal sample fecal samples gastrointestinal system gastrointestinal tract gastrointestinal tracts Gut gut microbiota gut-lung axis Health Organization immune immune response immune responses increased mortality Infectious disease Inflammation Interaction intestinal involved lung Lungs manifestation Manifestations mechanism microbiota modulation mucosa mucosal mucous membrane mucous membranes nasopharyngeal oesophagus other respiratory infections pathologic persistence Probiotics Prolonged rectum Regulatory respiratory respiratory and gastrointestinal tracts respiratory infections respiratory mucosa Respiratory system SARS-CoV-2 SARS-CoV-2 clearance SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 stomach target the healthy Therapeutic approach therapy virus WHO World Health Organization [DOI] 10.3389/fimmu.2021.635471 PMC 바로가기 [Article Type] Review
Intra-host variation and evolutionary dynamics of SARS-CoV-2 populations in COVID-19 patientsCOVID-19 환자에서 SARS-CoV-2 집단의 숙주 내 변이 및 진화 역학Research Published on 2021-02-222022-08-13 Journal: Genome Medicine [Category] MERS, 변종, 유전자 메커니즘, [키워드] allele frequency analyzed anatomic site bottleneck bottleneck events bottlenecks causative agent characterized collected Consensus consensus genome coronavirus COVID-19 COVID-19 patient death distribution driven by Dynamics eight event Evolution evolutionary dynamics gastrointestinal tract Genetic genetic diversity Genotype High-throughput sequencing Intra-host Intra-host variant iSNV iSNVs knowledge metatranscriptomic MOST Mutation nucleotide Patient patients with COVID-19 polymorphic site Population populations respiratory respiratory tract Result RNA viruses SARS-CoV-2 SARS-CoV-2 genome Sequencing Single nucleotide variant single nucleotide variation supplementary material the SARS-CoV-2 genome variants Variation Viral virus Virus-host interaction Virus-host interactions [DOI] 10.1186/s13073-021-00847-5 PMC 바로가기 [Article Type] Research
Probiotics potentials in mitigating coronavirus disease (COVID-19) pandemicCommentary Published on 2021-02-182022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, MERS, [키워드] administration Compound coronavirus disease COVID-19 COVID-19 pandemic exclusion gastrointestinal tract Health human infectious disease immune response immune responses Infection prevention lack Measures microbiota mitigate modulate modulation morbidities morbidity mortalities pandemic Pathogens prevention Probiotics reduction in secretion Severe respiratory distress shown therapeutic intervention [DOI] 10.11604/pamj.2021.38.186.27953 PMC 바로가기 [Article Type] Commentary
Gastrointestinal tract imaging findings in confirmed COVID-19 patients: a non-comparative observational studyResearch Published on 2021-02-102022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] Abdominal imaging studies bleeding bowel Chest classical Clinical data Complication complications of COVID-19 Computed tomography Corona virus correlation COVID-19 COVID-19 patient death Diagnosis diagnostic diarrhea disease evaluated feature FIVE Gastrointestinal gastrointestinal tract Highlights infection control Inflammatory Ischemic isolation hospital Laboratory measure nine Patient positive COVID-19 public health Result Retrospective study Symptom Symptoms the disease Thoracic were recorded [DOI] 10.1186/s43055-021-00433-0 PMC 바로가기 [Article Type] Research
COVID-19 Vaccination: From Interesting Agent to the PatientReview Published on 2021-02-032022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] agent Alter Analysis break down Central nervous system circulatory system coronavirus 2 COVID-19 drug development and discovery FDA approval Final function gastrointestinal tract globe help helping less organs pandemic reduce released Research respiratory SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Stage Stress the SARS-CoV-2 vaccination Vaccine viral family virus [DOI] 10.3390/vaccines9020120 PMC 바로가기 [Article Type] Review
Severe SARS-CoV-2 disease in the context of a NF-κB2 loss-of-function pathogenic variantNF-κB2 기능 상실 병원성 변이체의 맥락에서 심각한 SARS-CoV-2 질병Case Reports Published on 2021-02-012022-09-11 Journal: The Journal of Allergy and Clinical Immunology [Category] MERS, SARS, 변종, 진단, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus Affect affecting among others appear B-cell biologic biologic therapies cardiovascular system Central nervous system Clinical management combined immunodeficiency common variable immunodeficiency Complication coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease dysregulation evaluated functional Gain gain-of-function gastrointestinal tract global pandemic heterozygous variant heterozygous variants Hospitalization Host Host immune response hyperinflammatory responses immune immune dysfunction immune dysregulation immunodeficiency Infection intrinsic kidney loss of function loss-of-function Lungs male management mechanical ventilation memory B cells NF-κB NF-κB pathway NF-κB2 NFKB2 Novel coronavirus nuclear organ systems outcome pathogenic variant Patient patients with SARS-CoV-2 phenotype reported required respiratory respiratory distress Respiratory distress syndrome risk factor SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity of COVID-19 skin susceptible Symptom symptomatic SARS-CoV-2 infection syndrome therapy treat variant virus [DOI] 10.1016/j.jaci.2020.09.020 PMC 바로가기 [Article Type] Case Reports