To what extent is alcohol consumption in social gatherings associated with observance of COVID-19 restrictions? A rapid reviewCOVID-19 제한 준수와 관련된 사교 모임에서의 알코올 소비는 어느 정도입니까? 신속한 검토Review Published on 2022-07-252022-09-11 Journal: Journal of Global Health [Category] MERS, meta-analysis, [키워드] 95% confidence interval Abstract alcohol alcohol consumption association CINAHL Compliance conducted confounding factor confounding factors connection coronavirus COVID-19 Cross-sectional studies cross-sectional study database direction eligible event Evidence for inclusion global health Guidance help hygiene Intervention Joanna Briggs Institute measure Methodological quality moderate NPI NPIs observance Odds ratio OVID physical distancing Policy produced ProQuest Public public health measure public health measures public spaces recall bia recall bias reduced reported required Research risk Safe selection bia Selection bias social interaction statistically significant Study design suggested systematic review title understanding WHO with COVID-19 [DOI] 10.7189/jogh.12.13001 PMC 바로가기 [Article Type] Review
Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infectionSARS-CoV-2 감염 진단을 위한 신속한 현장 진료 항원 검사Review Published on 2022-07-222022-09-11 Journal: The Cochrane database of systematic reviews [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] 95% CI 95% confidence interval absence access Accuracy age Antigen antigen test antigen tests approach assays Asymptomatic average Bern bioRxiv brand can not carried Chain Reaction Characteristics checked CIs Cohort Compliance conducted COVID-19 COVID-19 pandemic COVID-19 testing criteria criterion Data collection database demonstrated described detect diagnosis of SARS-CoV-2 diagnostic Diagnostic accuracy diagnostic tests Effectiveness eligible epidemiological estimate Europe evaluate evaluated Evidence exposure to False positive False positives global health groups Health Organization healthcare help heterogeneity highest include independent indication Infection Interpretation investigated logistic regression models management Mass screening measure medRxiv molecular test National Open Access Other participant Participants Patient care point-of-care polymerase chain polymerase chain reaction population groups Positive predictive value positive result PPV Predictive value presence or absence Prevalence produced public health QUADAS-2 random-effect ranged Rapid rapid antigen test Rapid antigen tests Rapid diagnostic test reduce reducing reference reference standard Reference standards repeated reported Research respiratory respiratory sample resulting reverse transcription reverse transcription polymerase chain reaction RT-PCR RT-PCR testing SARS-CoV-2 SARS-COV-2 infection Schools screened screening procedure screening programmes searched second Selection sensitivities sensitivity Sensitivity and specificity Seven Signs and symptoms Source Specificities specificity study cohort Study design Symptom symptom onset symptom status symptomatic symptomatic and asymptomatic symptomatic participant symptomatic participants symptomatic people symptoms of COVID-19 test negative test result Testing to define Transmission Triage unique University of Bern variable Viral Viral load viral loads website were used WHO World Health Organization [DOI] 10.1002/14651858.CD013705.pub3 PMC 바로가기 [Article Type] Review
The usefulness of D-dimer as a predictive marker for mortality in patients with COVID-19 hospitalized during the first wave in Italy이탈리아의 첫 번째 물결 동안 입원한 COVID-19 환자의 사망률에 대한 예측 마커로서 D-dimer의 유용성Article Published on 2022-07-222022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] addition age Analysis assist C-index Clinical characteristics co-morbidity cohort study competing coronavirus disease Coronavirus disease 2019 COVID-19 cumulative cumulative incidence D-dimer death diagnosed with COVID-19 died dimer First wave global health Health healthcare hospital Hospital mortality Hospitalized hospitalized patient hospitalized patients identification in-hospital mortality incidence Italy lead lombardy majority marker medical staff Model moderate morbidities Mortality occurred outcome Patient patient records patients patients with COVID-19 performed Predictive Predictive value predictor primary endpoint Real-time PCR resources risk Sex statistical analyses study population survival Treatment was obtained [DOI] 10.1371/journal.pone.0264106 PMC 바로가기 [Article Type] Article
Specific CD4+ T Cell Responses to Ancestral SARS-CoV-2 in Children Increase With Age and Show Cross-Reactivity to Beta Variant어린이의 조상 SARS-CoV-2에 대한 특정 CD4+ T 세포 반응은 나이가 들어감에 따라 증가하고 베타 변이체에 대한 교차 반응성을 나타냅니다Article Published on 2022-07-152022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] accompanied Activation activation induced marker (AIM) activation-induced marker activation-induced markers age ancestral Antiviral average Beta Beta variant beta variants Blood CD4+ CD4+ T cell children Control convalescent coronavirus COVID-19 cross-reactivity Cytokines cytometric disease course Effective vaccines Flow global health granzyme granzyme B HCoV Health human coronavirus human coronavirus (HCoV) IFN-γ immune response increase Infection infection rate infection rates marker Mild mononuclear cell PBMC pediatric peptide peripheral Peripheral blood Peripheral blood mononuclear cells reduced reduction response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant secreted cytokine secretion seronegative show social distancing measures Specific stimulated T cell T cell responses T cells the SARS-CoV-2 vaccination variant variant of concern (VOC) viral variant VoC was reduced were used [DOI] 10.3389/fimmu.2022.867577 PMC 바로가기 [Article Type] Article
A Comprehensive Review of Andrographis paniculata (Burm. f.) Nees and Its Constituents as Potential Lead Compounds for COVID-19 Drug DiscoveryCOVID-19 약물 발견을 위한 잠재적인 납 화합물로서 Andrographis paniculata(Burm. f.) Nees 및 그 구성 요소에 대한 포괄적인 검토Review Published on 2022-07-132022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 치료제, [키워드] 3CLpro activity Andrographis paniculata Anti-inflammatory anti-inflammatory activity Antiviral antiviral activity argument Asian biological properties clinical trial clinical trials Combination complementary Compound Comprehensive Constituent COVID-19 COVID-19 pandemic COVID-19 treatment Critical demonstrated drug Drug discovery early treatment economics Efficacy global health hACE2 Health immunomodulatory immunomodulatory activity in silico in vitro study Infection information ingredient inhibit lead compound Manifestations natural product pharmacological Placebo Potential Prophylaxis Randomized controlled trial Randomized controlled trials reducing review SARS-CoV-2 severity Side effects Support target protein Treatment treatment for COVID-19 upper respiratory tract upper respiratory tract infection URTI virion production Well-being [DOI] 10.3390/molecules27144479 PMC 바로가기 [Article Type] Review
Analysis of the docking property of host variants of hACE2 for SARS-CoV-2 in a large cohort대규모 코호트에서 SARS-CoV-2에 대한 hACE2의 숙주 변이체의 도킹 특성 분석Article Published on 2022-07-112022-09-11 Journal: PLoS Computational Biology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed angiotensin binding free energy caused coronavirus coronavirus disease COVID-19 COVID-19 infection Diagnosis docking free energy genetic diversity genomic data global health hACE2 Health Host human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 human cells individual individuals Interaction large cohort missense variant Mobility molecular molecular dynamics Molecular dynamics simulation molecular interaction Novel coronavirus novel coronavirus disease outbreak physical provided receptor SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 infections selected severe acute respiratory syndrome Coronavirus Spike protein subject the spike protein UK biobank variant [DOI] 10.1371/journal.pcbi.1009834 PMC 바로가기 [Article Type] Article
Controlling SARS-CoV-2 in schools using repetitive testing strategies반복적인 테스트 전략을 사용하여 학교에서 SARS-CoV-2 제어Article Published on 2022-07-052022-09-11 Journal: eLife [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] absenteeism Administered Analysis approach approved attack rate Child children class contrary controlling COVID-19 Epidemic epidemic control Epidemiology global health Human Infection Infectious disease Intervention Isolation Microbiology mitigate Number of school positive primary school reactive reduce reduced repetitive testing. SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant School Schools screened significantly Spread symptomatic symptomatic individual symptomatic individuals the epidemic the SARS-CoV-2 thresholds time intervals triggered vaccination Vaccine while [DOI] 10.7554/eLife.75593 PMC 바로가기 [Article Type] Article
COVID-19 attributed mortality and ambient temperature: a global ecological study using a two-stage regression modelArticle Published on 2022-07-012023-07-07 Journal: Pathogens and global health [Category] COVID19(2023년), [키워드] COVID-19 Environment and public health global health Government Mortality temperature [DOI] 10.1080/20477724.2021.2007336 PMC 바로가기
Comparative characterization of SARS-CoV-2 variants of concern and mouse-adapted strains in mice마우스에서 우려되는 SARS-CoV-2 변이체 및 마우스 적응 균주의 비교 특성화Comparative Study Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha Alpha variant Amino acid Beta Beta variant caused changes in comparable Comparative cytokine cytokine assay Delta delta variant Evolution of SARS-CoV-2 global health Health highlighting Human indicated infect investigated isolates Laboratory lung Lung pathology Lungs MASCp6 mice Mild mouse-adapted strain mouse-adapted strains Mutation pathogenic pathogenicity raising RBD Receptor-binding domain Replication risk SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 mouse-adapted strains SARS-CoV-2 variant SARS-CoV-2 variants spillover risk sustained the RBD the receptor-binding domain variant variants variants of concern VoC VOCs wildtype [DOI] 10.1002/jmv.27735 PMC 바로가기 [Article Type] Comparative Study
Effects of Spike Mutations in SARS-CoV-2 Variants of Concern on Human or Animal ACE2-Mediated Virus Entry and Neutralization인간 또는 동물 ACE2 매개 바이러스 진입 및 중화에 대한 우려의 SARS-CoV-2 변이체에서 스파이크 돌연변이의 영향Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Affect angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 animal animals antibodies antibody Antibody neutralization antibody neutralization activity Beta caused cell entry cell line cell lines circulating common strain comparable concern coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Delta determine Effect Effectiveness Efficiency Express expressing global health Health host range Human human ACE2 Impact infect infecting information mink MOST Mutation neutralization neutralizing antibody Neutralizing titer neutralizing titers nine omicron Omicron variant over pandemic parental Protein pseudovirus pseudoviruses public policy reduced respiratory reveal S protein S proteins SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 mutation SARS-CoV-2 S protein SARS-CoV-2 spike SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus sera several variant several variants severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown significantly socioeconomics spike spike mutations Spread Substitution substitutions Support susceptible tested the S protein the SARS-CoV-2 the SARS-CoV-2 virus therapeutic therapeutic antibodies Transmissibility Transmission Vaccine variant variants variants of concern variety Viral viral cell viral entry viral neutralization virulence virus virus entry virus replication VoC VOCs zoonotic [DOI] 10.1128/spectrum.01789-21 PMC 바로가기 [Article Type] Article