Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomised controlled trialHIV의 2차 치료를 위한 로피나비르 + 뉴클레오시드 역전사효소 억제제, 로피나비르 + 랄테그라비르 또는 로피나비르 단독요법(EARNEST): 무작위 대조 시험의 144주 추적 결과Article Published on 2018-01-012022-09-06 Journal: The Lancet. Infectious Diseases [Category] Communicable Disease, [키워드] adverse event African AID analysed Analysis Antiretroviral therapy ART assigned best clinical Combination combination therapy completion computer-generated cooperation country criteria Developing development Efficacy eligibility European event finding FIVE Follow-up funding GRADE grade 3 group HIV-infected people inferiority inhibitor inhibitors intervention group ISRCTN Kenya less limit Lopinavir Medical Research Council Modification monotherapy no difference non-inferiority non-inferiority margin nucleoside offer offered outcome participant partnership Patient per day primary analysis Primary outcome protease Protease inhibitor raltegravir randomisation randomised controlled trial Randomly receive recent regimen regimens Registered Ritonavir screened sequence Serious Adverse Events Swedish Treatment treatment of HIV Trial two-sided α Uganda Viral Viral load viral loads Virological WHO WHO criteria WHO guideline Zimbabwe [DOI] 10.1016/S1473-3099(17)30630-8 PMC 바로가기 [Article Type] Article
Protease inhibitor monotherapy for long-term management of HIV infection: a randomised, controlled, open-label, non-inferiority trialHIV 감염의 장기 관리를 위한 프로테아제 억제제 단독 요법: 무작위, 대조, 공개, 비열등성 시험Articles Published on 2015-09-142022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] 1:1 adverse event age Antiretroviral therapy ART baseline benefit block CD4 Cell Clinical management Clinical outcome clinical risk Combination combination treatment computer-generated Controlled darunavir defined drug drug resistance enrolled finding Frequency funding Genetic GRADE grade 3 HIV HIV infection inferiority inhibitor Intention intention to treat international standard Kaplan-Meier Kaplan-Meier analysis Lopinavir maintain management monotherapy non-inferiority non-inferiority margin non-inferiority trial number once daily Open-label parallel-group participant positive Pragmatic preserved Primary outcome Probability Protease inhibitor protease inhibitors public sector randomisation randomisation list randomised Randomly rebound Registered Ritonavir Serious Adverse Events shown Standard stratified suppressed the patient therapy toxic effects Treatment treatment failure Trial Viral Viral load virus [DOI] 10.1016/S2352-3018(15)00176-9 PMC 바로가기 [Article Type] Articles
Review of the safety and efficacy of vitamin A supplementation in the treatment of children with severe acute malnutrition심각한 급성 영양실조 아동 치료에서 비타민 A 보충의 안전성과 효능에 대한 검토Review Published on 2013-09-122024-07-30 Journal: Nutrition Journal [Category] 세균성이질, [키워드] GRADE Severe acute malnutrition systematic review Vitamin A supplementation [DOI] 10.1186/1475-2891-12-125 PMC 바로가기 [Article Type] Review