Von Willebrand factor collagen-binding capacity predicts in-hospital mortality in COVID-19 patients: insight from VWF/ADAMTS13 ratio imbalance폰 빌레브란트 인자 콜라겐 결합 능력은 COVID-19 환자의 병원 내 사망률을 예측합니다: VWF/ADAMTS13 비율 불균형으로부터의 통찰력Article Published on 2021-08-012022-09-11 Journal: Angiogenesis [Category] SARS, 바이오마커, [키워드] 48 hour 48 hours 95% CI ADAMTS13 adjusted Admission Analysis AUC balance best Biomarker BMI C-reactive protein collagen Collagen-binding COVID-19 COVID-19 severity Critical cut-off D-dimer levels described enrolled hallmark hazard Hospital mortality hospitalized COVID-19 patient in-hospital mortality IQR Kaplan-Meier estimator median Microthrombosis molecular weight Mortality Multimers Patient Plasma level Plasma levels predict Predictive ROC Curve shown significantly subsequent Trigger von Willebrand factor vWF was increased were measured [DOI] 10.1007/s10456-021-09789-3 PMC 바로가기 [Article Type] Article
Body mass index and risk of COVID-19 diagnosis, hospitalisation, and death: a cohort study of 2 524 926 Catalans체질량 지수와 COVID-19 진단, 입원 및 사망 위험: 2 524 926 카탈로니아인에 대한 코호트 연구Clinical Research Article Published on 2021-07-232022-09-12 Journal: The Journal of Clinical Endocrinology and Metaboli [Category] MERS, 진단, [키워드] 95%CI Adiposity age and sex association BMI BMIs body mass body mass index Care cohort study Context COVID-19 COVID-19 diagnosis death diagnosed diagnosed with COVID-19 Diagnosis Electronic health records fatality Follow-up hazard hazard ratios Height higher risk hospital hospitalisation hospitalisation with COVID-19 hospitalised increase in individual mechanism Modification Mortality obesity objective outcome outcome measure participant Participants Research Result risk risk of COVID-19 SARS-CoV-2 setting subsequent weight with COVID-19 younger patients [DOI] 10.1210/clinem/dgab546 PMC 바로가기 [Article Type] Clinical Research Article
Healthcare workers’ perspectives on coronavirus testing availability: a cross sectional survey코로나 바이러스 테스트 가용성에 대한 의료 종사자의 관점 : 단면 조사Research Published on 2021-07-212022-09-01 Journal: BMC health services research [Category] SARS, 진단, [키워드] Access to testing Administrator age association Boston changes in coronavirus COVID cross cross-sectional survey Disparities employment female First wave hazard HCW HCWs healthcare worker Healthcare workers hospital Human resources include less life Massachusett Massachusetts multivariable model Multivariable models novel SARS-CoV-2 virus Nurse Nurses pandemic Patient Perspective Quality of life receipt receive receiving resource respondent response Result SARS-CoV-2 virus sick supplementary material Support vaccination variable were used Worry [DOI] 10.1186/s12913-021-06741-5 PMC 바로가기 [Article Type] Research
Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platformResearch Published on 2021-07-152022-10-28 Journal: The BMJ [Category] COVID-19, [키워드] 95% confidence interval adjusted age association associations Care cause children cohort study death deaths defined Electronic health record England estimates event rate exposure group geographical location greater hazard hazard ratio healthcare hospital Hospital admission increased risk NHS objective office OpenSAFELY outcome measure participant platform Population preventive measure produced Registered Result risk secondary service setting Sex Statistics syndrome vaccination Wave [DOI] 10.1136/bmj.n1592 PMC 바로가기 [Article Type] Research
Inflammatory and Hypercoagulable Biomarkers and Clinical Outcomes in COVID-19 PatientsArticle Published on 2021-07-132022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% confidence interval abnormality Admission baseline Biomarker cardiovascular disease clinical clinically Combination Concordance contribute coronavirus disease COVID-19 COVID-19 patient CRP cumulative CVD D-dimer D-dimer level D-dimer value enrolled hazard hospitalized patient In-hospital in-hospital mortality in-hospital mortality rate Inflammation interquartile range Japanese lowest median age multicenter observational study outcome pathophysiological Patient retrospective risk risk factor Society stratified supported systemic the median threshold [DOI] 10.3390/jcm10143086 PMC 바로가기 [Article Type] Article
Longitudinal Analysis of the Utility of Liver Biochemistry as Prognostic Markers in Hospitalized Patients With Corona Virus Disease 2019Original Article Published on 2021-07-102022-10-31 Journal: Hepatology communications [Category] COVID-19, [키워드] 95% CI 95% confidence interval acute respiratory syndrome adjusted adjusted hazard ratio age alanine aminotransferase albumin alkaline phosphatase ALP association baseline Biochemistry Clinical data Clinical outcome Cohort collected Corona coronavirus COVID‐19 death declined determine develop died disease elevated hazard hospital hospitalized patient Infection liver Liver disease longitudinal measure Mortality outcome Patient positive preexisting comorbidities Prognostic marker proportion required rising RT‐PCR SARS‐CoV‐2 Sex significantly higher United Kingdom utility [DOI] 10.1002/hep4.1739 PMC 바로가기 [Article Type] Original Article
Umifenovir in hospitalized moderate to severe COVID-19 patients: A randomized clinical trialReview Published on 2021-07-102022-10-04 Journal: International immunopharmacology [Category] 임상, 치료제, [키워드] ABG, Atrial blood gas Analysis Arbidol assigned Chest CT scans Clinical improvement clinical trial Committee conducted Control control group control groups COVID-19 COVID-2019, Coronavirus Disease 2019 Cox regression model dose effective Effectiveness Efficacy Ethics evaluate GCS, Glasgow Coma Scale hazard Hospitalized hospitalized patient HR, hazard ratio ICU, Intensive care unit Infection injection Intervention intervention group ITT population legally authorized representatives LFT, liver function test median Medical Sciences moderate moderate-severe Mortality non-ICU patient Open-label participant Patient positive positive RT-PCR Prognosis Randomized randomized clinical trial Randomly Ratio receive Registered Result SARS-CoV-2 SARS-CoV-2, severe acute respiratory syndrome coronavirus2 severe COVID-19 Severe patient single-center statistically significant statistically significant difference Subcutaneous time treat treated Treatment treatment group Trial TTCI TTCI, Time to clinical improvement two group umifenovir university VBG, Venous blood gas [DOI] 10.1016/j.intimp.2021.107969 PMC 바로가기 [Article Type] Review
Clinical Outcomes of Severe COVID-19 Patients Admitted to an Intermediate Respiratory Care UnitMedicine Published on 2021-07-012022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95%CI age Chronic kidney disease chronic respiratory chronic respiratory condition clinical Clinical outcome clinical outcomes condition COVID-19 Cox proportional hazard death dose Follow-up hazard health-care High-flow nasal cannula ICU IMCU intensive care intermediate intermediate care unit IQR lower risk male management median age Mortality mortality rate multivariable Non-invasive non-invasive ventilation Patient Patient care Pneumonia protective effect reducing renal required resource respiratory Respiratory care Respiratory Support Retrospective study risk factor severe COVID-19 patient stratified survival systemic corticosteroid transfer transferred Treatment unit was used [DOI] 10.3389/fmed.2021.711027 PMC 바로가기 [Article Type] Medicine
Tocilizumab in COVID-19: Factors Associated With Mortality Before and After TreatmentPharmacology Published on 2021-07-012022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 95% CI addition Administered administration age Analysis average baseline C-reactive protein Cohort Comorbidity COVID-19 COVID-19 diagnosed patient Cox regression model death Deceased Diabetes Mellitus Diagnosis discharged discharged patients early treatment Factor had more hazard hospitalized patient Immunosuppression immunosupression laboratory parameter Laboratory parameters lactate dehydrogenase lymphocyte Mortality neutrophil PaO Patient Platelet predictor receiving risk risk factor risk of death SARS-CoV-2 pneumonia TCZ the mean Tocilizumab Treatment troponin I variable were used with COVID-19 [DOI] 10.3389/fphar.2021.620187 PMC 바로가기 [Article Type] Pharmacology
COVID-19′s Impact on American Women’s Food Insecurity Foreshadows Vulnerabilities to Climate ChangeReview Published on 2021-06-262022-10-30 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] amplified buffer build change Climate Climate change COVID-19 COVID-19 pandemic Effect environmental health equity feedback loops food food insecurity Food security Gender green hazard help highlighting identify Impact include increasingly insecurity lack negative feedback loop New Deal Resilience risk vulnerability [DOI] 10.3390/ijerph18136867 PMC 바로가기 [Article Type] Review