Heart rate variability follow-up during COVID-19 -a case reportCOVID-19 중 심박수 변동 추적 - 증례 보고Case Reports Published on 2022-02-012022-09-11 Journal: Korean journal of anesthesiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] ambulatory Ambulatory monitoring Asthma Autonomic nervous system Case report Computer-assisted signal processing COVID-19 COVID-19 infection COVID-19 infections deleterious effect deleterious effects detect Follow-up heart heart rate HRV hypertension increase in Inflammatory response moderate modulation nervous system obese parasympathetic Population reached reduced Standard deviation Symptoms the disease Variability wearable electronic devices [DOI] 10.4097/kja.21338 PMC 바로가기 [Article Type] Case Reports
Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart심장 SARS-CoV-2 감염은 심장 내 전염증성 전사체 변화와 관련이 있습니다Article Published on 2022-01-292022-09-11 Journal: Cardiovascular Research [Category] SARS, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] adverse outcome Analysis Atla Autopsy cardiac Cardiac infection Cardiac signature matrix caused cDNA Cell consequence COVID-19 Cytometry Deceased DEGs destruction Diagnosis differentially expressed gene downregulated Effects endothelial Endothelial cell endothelial cells fraction Gene ontology GO term heart heart tissue ICAM1 identify IFI44L Immune cell Immune cell infiltration immune response Immunofluorescent staining immunohistochemistry In situ hybridization Increased Infection interferon interferon pathway investigated MACE marker massive molecular MYPN no difference NPPB paracrine Pathomechanism positive pro-inflammatory pro-inflammatory gene expression q-value Quantitative reveal RNA-Seq RNA-sequencing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus sequencing data signature matrix single-cell dataset staining tissue transcriptomic alteration TRIM25 upregulated Viral Viral protein virus virus load was performed while [DOI] 10.1093/cvr/cvab322 PMC 바로가기 [Article Type] Article
Effect of Face Masks on Blood Saturation, Heart Rate, and Well-Being Indicators in Health Care Providers Working in Specialized COVID-19 CenterArticle Published on 2022-01-262022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] Affect Blood Care center concerning COVID-19 Covidien decrease Effect face Face masks fatigue FFP2 respirator hcp Health heart heart rate hospitals Indicator Mask median oxygen saturation Personal protective equipment questionnaire Rate real time Safe SARS-CoV-2 saturation subject USA wearing face mask were measured working [DOI] 10.3390/ijerph19031397 PMC 바로가기 [Article Type] Article
Clinico-histopathologic and single-nuclei RNA-sequencing insights into cardiac injury and microthrombi in critical COVID-19중요한 COVID-19에서 심장 손상 및 미세 혈전에 대한 임상 조직 병리학 및 단일 핵 RNA 시퀀싱 통찰력Clinical Trial Published on 2022-01-252022-09-10 Journal: JCI Insight [Category] 임상, 진단, 치료기술, 치료제, [키워드] Acute cardiac injury Analysis antiplatelet association bioinformatics Biomarkers biomarkers of inflammation C-reactive protein cardiac injury Cardiology cardiovascular disease cause clinical factors Cohort conducted controls Corticosteroid corticosteroid treatment COVID-19 Critical enrichment erythrocyte sedimentation erythrocyte sedimentation rate etiology Extracellular matrix Features fibrinolysis fibroblast heart hearts identify In-hospital increased mortality Injury microthrombi Molecular pathology myocarditis Necrosis New York City pathophysiology Patient potential therapeutic target prevalent Prospective Study RNA-sequencing sedimentation rate Sequencing analysis Signaling tested therapeutic anticoagulation Therapies therapy transcriptomic were used [DOI] 10.1172/jci.insight.154633 PMC 바로가기 [Article Type] Clinical Trial
Studying the clinical, radiological, histological, microbiological, and immunological evolution during the different COVID-19 disease stages using minimal invasive autopsy최소 침습성 부검을 사용하여 상이한 COVID-19 질병 단계 동안 임상, 방사선 학적, 조직 학적, 미생물 학적 및 면역 학적 진화 연구Clinical Trial Published on 2022-01-252022-09-01 Journal: Scientific Reports [Category] 임상, 진단, 치료법, [키워드] alveolar damage America Autopsy change Characteristics clinical microbiology Cohort COVID-19 COVID-19 disease COVID-19 patients diffuse Diffuse alveolar damage disease evaluated Evolution had no heart histological histopathological IgG immunological immunological characteristics Immunopathogenesis Infection Inflammation interferon interferon-γ invasive liver organ Other other organs Pathogenesis pathophysiological mechanism pathophysiological mechanisms Patient PCR-confirmed COVID-19 patient positive radiological Significant significant differences significantly higher Society Stage stages Treatment viral infection WHO with COVID-19 [DOI] 10.1038/s41598-022-05186-y PMC 바로가기 [Article Type] Clinical Trial
System-wide transcriptome damage and tissue identity loss in COVID-19 patientsCOVID-19 환자의 시스템 전체 전사체 손상 및 조직 정체성 상실Article Published on 2022-01-242022-09-10 Journal: Cell Reports Medicine [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] Abstract acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ARDS Autopsy Bacterial infection canonical Cell cell type cellular Clinical course clinical manifestation clinical manifestations Cluster co-occurrence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient disrupt evere acute respiratory syndrome coronavirus 2 expression expression profiling fibroblast functional heart host response identify identity immune cell population immune cell populations increase in Infection Influenza Influenza virus kidney liver lung Lung injury lymph nodes marker molecular molecular dynamics molecular mechanism molecular mechanisms Mortality multiple organ multiple organs Nasopharyngeal swab Next-generation sequencing NGS organs other respiratory infections park pathway Patient Protein respiratory respiratory distress respiratory infections RNA-Seq SARS-CoV-2 SARS-CoV-2 viral load SARS-CoV-2 viral loads Seasonal influenza severe acute respiratory syndrome Coronavirus spatial transcriptomics spatiotemporal subsequent syndrome systemic disruption These data tissue tissues to define transcriptional Transcriptome transcriptome change Viral Viral load viral loads virus wrought [DOI] 10.1016/j.xcrm.2022.100522 PMC 바로가기 [Article Type] Article
Overexpression of the SARS-CoV-2 receptor angiotensin converting enzyme 2 in cardiomyocytes of failing heartsArticle Published on 2022-01-192022-10-04 Journal: Scientific Reports [Category] 바이오마커, [키워드] ACE2 ACE2 expression ACE2 receptor Biochemistry Biomarkers Biotechnology Cardiology cardiovascular comorbidity Cell Biology dependent on disease Diseases Donor Endothelial cell endothelial cells enzyme expressed expression fibroblast fibroblasts healthy donor heart heart failure hearts immunohistochemistry immunology in both groups infect cells Medical research Molecular biology Molecular medicine myocarditis organ outcome Patient Physiology proteomics Quantitative receptor risk RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus subpopulation the SARS-CoV-2 tissue ventricular was measured was used [DOI] 10.1038/s41598-022-04956-y PMC 바로가기 [Article Type] Article
Cardiac Manifestations in Patients with COVID-19: A Scoping ReviewOriginal Research Published on 2022-01-122022-10-31 Journal: Global Heart [Category] COVID-19, SARS, [키워드] Acute cardiac injury Acute coronary syndrome adult COVID-19 patients Affect arrhythmia Arrhythmias article association Biomarker bioRxiv cardiac cardiac adverse event cardiac complication cardiac failure cardiac injury clinical parameter clinically complications conducted coronary syndrome Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patients determine disease severity Frequency heart Heart diseases heterogenous Hospitalization identify inclusion criteria Infection Inflammation inhibitor Injury Lungs manifestation Manifestations Mortality MOST myocarditis non-severe patients on type Other other organs outcome prevalent Prognosis provided randomized trial ranged renin-angiotensin-aldosterone system reported Respiratory failure review screened severe disease severity Support susceptibility systematic review therapeutic Therapeutic approach with COVID-19 [DOI] 10.5334/gh.1037 PMC 바로가기 [Article Type] Original Research
Systematic identification of ACE2 expression modulators reveals cardiomyopathy as a risk factor for mortality in COVID-19 patientsACE2 발현 조절제의 체계적인 식별은 심근병증을 COVID-19 환자의 사망 위험 인자로 밝혀줍니다Research Published on 2022-01-102022-09-11 Journal: Genome Biology [Category] 유전자 메커니즘, [키워드] ACE2 ACE2 expression Analysis angiotensin angiotensin-converting enzyme 2 Cardiomyopathy cardiovascular conditions categories characterized Comprehensive condition COVID-19 illness COVID-19 patient COVID-19 patients Critical dataset datasets develop disease drug drug treatment drug treatments drugs Electronic health record Electronic health records enzyme expression Genetic healthy heart HNF1A human tissue identify increased mortality Infection itraconazole joint Mortality overexpression Pathogenesis pathogenesis of COVID-19 Patient perturbations RAD140 receptor Result reveal risk risk factor Risk factors RNA-Seq SARS-CoV-2 SARS-COV-2 infection Seven severe COVID-19 illness supplementary material Transmission upregulation variance while [DOI] 10.1186/s13059-021-02589-4 PMC 바로가기 [Article Type] Research
Pandemic Influenza Infection Promotes Streptococcus pneumoniae Infiltration, Necrotic Damage, and Proteomic Remodeling in the Heart전염병 인플루엔자 감염은 심장에서 폐렴구균 침투, 괴사성 손상 및 단백질체 재구성을 촉진한다.Article Published on 2022-01-042024-07-30 Journal: mBio [Category] 폐렴구균 감염증, [키워드] adhesion heart Influenza necroptosis Pneumolysin pore-forming toxins proteomics Secondary bacterial infections Streptococcus pneumoniae [DOI] 10.1128/mbio.03257-21 PMC 바로가기