Cloud-Based System for Effective Surveillance and Control of COVID-19: Useful Experiences From Hubei, ChinaOriginal Paper Published on 2020-04-222022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] Analysis assigned build Care China clinical decision Clinical decision support clinical effectiveness cloud system Control COVID-19 diagnostic discharged patients disease effective effort electronic medical records Epidemic Evidence experience Factor feasible Follow-up Health hybrid IMPROVE include media Medical informatics Medical resources objective pandemic Patient care provided real time resources Result shown stakeholders involvement Standardization statistical Support Surveillance Syndromic surveillance System [DOI] 10.2196/18948 PMC 바로가기 [Article Type] Original Paper
Which species is in the faeces at a time of global livestock movements: single nucleotide polymorphism genotyping assays for the differentiation of Fasciola sppArticle Published on 2020-02-012023-06-22 Journal: International journal for parasitology [Category] 조류인플루엔자, [키워드] Ante-mortem Fasciolosis hybrid Lao PDR molecular diagnostics Southeast Asia [DOI] 10.1016/j.ijpara.2019.12.002
Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from DubaiObservation Published on 2020-01-222022-10-30 Journal: mSphere [Category] Coronavirus, MERS, [키워드] 95% confidence interval acute respiratory syndrome addition affected antibodies antibody Antibody test Bactrian camel Camel China coronavirus correlation Dubai enzyme-linked immunosorbent etiological agent examined Fatality rate greater hybrid hybrid camel Infection intranasally MERS MERS coronavirus MERS-CoV MERS-CoV infection Middle East Mortality neutralization neutralizing antibody titers positive respiratory sera Seroconversion SEROLOGICAL STUDY serum sample Spearman coefficient syndrome tested United Arab Emirate virus Xinjiang [DOI] 10.1128/mSphere.00898-19 PMC 바로가기 [Article Type] Observation
A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivityGWAS 접근 방식은 Dapp1을 대기 오염 유발 기도 과민 반응의 결정 요인으로 식별합니다.Research Article Published on 2019-12-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence AhR air pollutant Air pollution airway airways approach association Asthma Author chromosome chromosome 19 chromosome 3 chromosomes chronic inflammatory disease condition Dapp1 diesel exhaust Diversity exhibited exposure to expressed Factor Genes Genetic genetic architecture genetic determinant genetic determinants genetic factors Genome-wide association studies Genome-wide association study GWAS HMDP Human humans hybrid Hyperreactivity identify IL33 inbred strains inherent Interaction interactions invasive linear mixed model loci locus lung Lung function mapped mice modulate mouse mucosal tissues Panel Particle phenotype risk significantly significantly lower strain Support susceptibility loci while [DOI] 10.1371/journal.pgen.1008528 PMC 바로가기 [Article Type] Research Article
Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania실험 하이브리드의 전체 게놈 시퀀싱은 Leishmania에서 감수 분열과 같은 성적 재조합을 지원합니다Research Article Published on 2019-05-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele approach backcross breakpoint Cell Cell fusion chromosomal chromosome chromosomes classical clone Culture demonstrated described determine division event Evidence expected Frequency Gain Genes Genetic genetic analysis genetic map Genome Genotype genus growth heterozygosity heterozygous homologous homologous chromosomes homozygous hybrid instance isolate Leishmania loss of heterozygosity marker meiosis mitotic occur offspring parental parents physical position presenting progeny Recombination sequenced Sequencing sexual cycle species Stage strain Strong Support undergo vector while whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1008042 PMC 바로가기 [Article Type] Research Article
Evolution of a novel chimeric maltotriose transporter in Saccharomyces eubayanus from parent proteins unable to perform this function이 기능을 수행할 수 없는 모 단백질로부터 Saccharomyces eubayanus의 새로운 키메라 말토트리오스 수송체의 진화Research Article Published on 2019-04-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptive breakpoint bypassing Cell changes in Chimera chimeric classic Deleterious determine domain duplicate gene ectopic recombination epistatic interaction epistatic interactions Evolution example experiment function functional functions gene encoding Gene Expression gene sequence generate genes encoding Genetic hybrid Interaction lack less limit locus MALT malt extract maltose maltotriose mapped molecular multiple mutation multiple mutations occurred overexpressing paralog paralogs performed Point mutation proceed Protein Proteins provide Recombination Research Saccharomyces cerevisiae sequence strain Strains Substitution substitutions sugar Support the cell thought Transport transporter while wild strain wild strains yeast [DOI] 10.1371/journal.pgen.1007786 PMC 바로가기 [Article Type] Research Article
Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States미국 내 다양한 민족의 여러 인구에서 심혈관 질환 및 제2형 당뇨병에 대한 공유 유전 조절 네트워크Research Article Published on 2017-09-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activity African Americans alterations American Americans Amino acid amino acid metabolism amino acids biological processe biological processes branched-chain amino acids cardiovascular cardiovascular disease cardiovascular diseases cause causes CAV1 Cell culture co-expression Cohort commonality complex disease connection Critical CVD data-driven death diabetes disease Diseases Diversity driven by driver ENCODE Epidemics eQTLs expression expression quantitative trait loci Extracellular matrix finding FIVE functional Functional genomics gene knockout gene network gene networks Genetic genetic risk Genome-wide association study Glucose graphical models GWAS GWAS hit help Hispanic HMGCR human population human populations hybrid identify IGF1 immune response in vitro in vivo information Integrative analysis knockdown lipids loci mechanism metabolism molecular molecular network mouse Mouse models multidimensional multiple tissues network models neuronal offer overlapping Panel Pathogenesis pathogenic pathogenic processe pathway Pathways PCOLCE Population populations Quantitative Regulatory regulatory network Risk factors shared pathway shared pathways siRNA Strains Support T2D the United State therapeutic therapeutic target tissues type 2 diabete type 2 diabetes [DOI] 10.1371/journal.pgen.1007040 PMC 바로가기 [Article Type] Research Article
A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues다중 상태 토글 스위치는 곰팡이 세포의 운명을 정의하고 시너지 유전 신호에 의해 조절됩니다Research Article Published on 2016-10-062022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accompany Analysis antagonistic can be used Candida tropicalis Cell cell differentiation cell fate cell type cell types cellular change chromatin Combination determined by ectopic ectopic expression Epigenetic event exhibit expression Fate Formation fungal fungi Gene Expression Gene expression profiles Genetic genetic analysis genetic regulation growth rates higher eukaryotes hybrid increase induce instances lack less master regulator multicellular organism multicellular organisms occurred opposite pathogen phenotypic Regulation stability stable cell stem cell switch switching synergistic to define transcription factor transcription factors transcriptional transcriptionally underlie unique Wor1 yeast [DOI] 10.1371/journal.pgen.1006353 PMC 바로가기 [Article Type] Research Article
The Seasonality and Ecology of the Anopheles gambiae complex (Dipetra: Culicidae) in Liberia Using Molecular Identificationarticle Published on 2015-05-312024-09-01 Journal: Annals of Medicine and Surgery [Category] 말라리아, [키워드] Anopheles gambiae hybrid molecular form PCR-RFLP [Article Type] article
Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cellsarticle Published on 2014-03-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] Artemisinin Cancer Egonol Ferrocene hybrid malaria [Article Type] article