L-Arginine supplementation in mice enhances NO production in spleen cells and inhibits Plasmodium yoelii transmission in mosquitoesL-아르기닌 보충이 쥐의 비장 세포에서 NO 생산을 증가시키고 모기에서 Plasmodium yoelii 전파를 억제한다.Research Published on 2015-06-142024-08-13 Journal: Parasites & Vectors [Category] 말라리아, [키워드] blood stage immune regulation L-Arginine Mosquito Plasmodium yoelii [DOI] 10.1186/s13071-015-0940-0 PMC 바로가기 [Article Type] Research
Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infectionarticle Published on 2015-01-312024-09-01 Journal: Neurogastroenterology and motility : the official [Category] 말라리아, [키워드] Cytokines immune regulation interferons malaria T helper cells [Article Type] article
Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis PneumoniaAIDS에 대한 케모카인 수용체 유전자의 외음성 변이의 역할: 폐포자충과의 CCRL2 F167Y 연관성Research Article Published on 2011-10-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 95% CI accelerated addition Affect AIDS Amino acid Analysis association associations Atypical Author CCR2 CCR3 CCR5 CCR8 CCRL2 Cell Chemokine receptor chromosome Cluster cohorts conditions CX3CR1 defined dendritic cell disease Disease progression DNA Effect exonic FIVE functional variant functional variants Gene Genes Genetic genetic association Genetic variation genotyped HIV-1 HIV-1 infection host cells Human immune regulation in addition to indicated Inflammation involved key factor lung majority natural history Non-synonymous outcome Pathogenesis Pneumonia progression role Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs surface protein survival survival analysis tested variant Variation [DOI] 10.1371/journal.pgen.1002328 PMC 바로가기 [Article Type] Research Article
A −436C>A Polymorphism in the Human FAS Gene Promoter Associated with Severe Childhood MalariaA −436C>심각한 아동기 말라리아와 관련된 인간 FAS 유전자 프로모터의 다형성Research Article Published on 2011-05-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] 95% confidence interval A allele a major activated affected allele Analysis Anemia Apoptosis applied assigned association Author carried Case-control caused CD69 Cell cell surface receptor cerebral malaria childhood children Community compared complex interplay complications Control Donor ENCODE Endemic Express expression FACS analysis FAS fatality found functional Genetic variant genetic variants genetics Health healthy individual help heterozygote homozygote homozygous Human Human genetics immune regulation immune response immune responses increased expression individual Infection investigated involved life-threatening locus lymphocyte Lymphocytes malaria molecule mononuclear cell mononuclear cells naïve nucleotide Occurrence Odds ratio outcome Pediatric case Peripheral blood Peripheral blood mononuclear cells phenotypic Plasmodium Plasmodium falciparum predisposition programmed cell death promoter promoter region proportion PROTECT Protective protective immune response Replication risk severe severe malaria significantly significantly higher Single nucleotide variant sub-Saharan Africa subgroup surface receptor susceptibility susceptible syndrome T-lymphocyte the disease Transmission dynamics variant West [DOI] 10.1371/journal.pgen.1002066 PMC 바로가기 [Article Type] Research Article