The effect of COVID-19 vaccination in Italy and perspectives for living with the virus이탈리아에서 코로나19 예방접종의 효과와 바이러스와 함께 살아가는 관점Article Published on 2021-12-142022-09-10 Journal: Nature Communications [Category] SARS, 변종, [키워드] absence age Computational models Coverage COVID-19 COVID-19 vaccination death delta variant Epidemic evaluate Health policy Increasing Infectious diseases Italy mathematical mathematical model offset Older pediatric Perspective physical distancing return Society summer vaccination Vaccine virus [DOI] 10.1038/s41467-021-27532-w PMC 바로가기 [Article Type] Article
The importance of saturating density dependence for population-level predictions of SARS-CoV-2 resurgence compared with density-independent or linearly density-dependent models, England, 23 March to 31 July 2020Research Published on 2021-12-092022-10-31 Journal: Eurosurveillance [Category] COVID-19, SARS, [키워드] Accuracy age classical consequence COVID-19 Deprivation deviate disease transmission distribution England Evidence form functional identifying impacted IMPROVE increase Infection Local lockdown mathematical mathematical model mortality data observation outbreak Pandemics Population population density projection proportion Result SARS-CoV-2 SARS-CoV-2 transmission Structure Transmission utility [DOI] 10.2807/1560-7917.ES.2021.26.49.2001809 PMC 바로가기 [Article Type] Research
Modeling serological testing to inform relaxation of social distancing for COVID-19 controlCOVID-19 통제를 위한 사회적 거리의 완화를 알리는 혈청학적 테스트 모델링Article Published on 2021-12-032022-09-10 Journal: Nature Communications [Category] 변종, 진단, 치료기술, [키워드] antibody benefit COVID-19 COVID-19 pandemic death Diseases finding Human behaviour Intervention mathematical mathematical model modeling New York City public health Puget Sound risk Serological testing seropositive individual seropositive individuals social distancing social interaction South state subsequent Transmission Transmission model variants viral infection Washington widespread [DOI] 10.1038/s41467-021-26774-y PMC 바로가기 [Article Type] Article
Modelling the concentration of anti-SARS-CoV-2 immunoglobulin G in intravenous immunoglobulin product batches정맥주사용 면역글로불린 제품 배치에서 항-SARS-CoV-2 면역글로불린 G의 농도 모델링Research Article Published on 2021-11-292022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus anti-SARS-CoV-2 anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG antibody antibody half-life antibody levels Antibody titre anticipated binding Concentration convalescent convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 Diseases Donor early phase elevated expected group half-life IgG Immunoglobulin implication incidence indicated Intravenous immunoglobulin IVIG mathematical mathematical model measurement parameter Patient Phadia physician plasma plasma concentration predict produced reactivity Result retained SARS-CoV-2 SARS-CoV-2 vaccination status Study design the mean Vaccination Status were used [DOI] 10.1371/journal.pone.0259731 PMC 바로가기 [Article Type] Research Article
Data-driven multi-scale mathematical modeling of SARS-CoV-2 infection reveals heterogeneity among COVID-19 patientsSARS-COV-2 감염의 데이터 중심의 다중 규모 수학적 모델링은 COVID-19 환자의 이질성을 나타냅니다.Research Article Published on 2021-11-242022-09-10 Journal: PLoS Computational Biology [Category] MERS, SARS, 치료제, [키워드] acute respiratory syndrome addition addressed Affect Analysis Antiviral antiviral therapy Asymptomatic Clinical data Combination combination therapies combination therapy coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus infections COVID-19 COVID-19 patient COVID-19 patients COVID-19 progression Critical Differential equations Disease progression Effect Efficacy evaluated exhibited Guidance heterogeneity heterogeneous highlight Host IFN IFN response immune responses Incubation period infected cell infected cells infected with SARS-CoV-2 infection process investigated lack late stage mathematical mathematical model moderate multicellular naïve T cell naïve T cells outcomes Patient patients production rate progression quantified Quantitative Quantitative analysis question respiratory reveal SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome severe patients severe symptom severe symptoms severity Simulation Stage suggested Symptom symptomatic Symptoms T cell T cell response T cell responses T cells the stage Therapeutic strategies therapeutic strategy therapy threshold transition treating COVID-19 patient treating COVID-19 patients Treatment strategies type I interferon Viral viral dynamics virus [DOI] 10.1371/journal.pcbi.1009587 PMC 바로가기 [Article Type] Research Article
Estimation of viral kinetics model parameters in young and aged SARS-CoV-2 infected macaquesMathematics Published on 2021-11-172022-10-28 Journal: Royal Society Open Science [Category] COVID-19, [키워드] Adults Ageing Antiviral treatment averaged cause caused COVID-19 cynomolgus macaque death estimate estimation in viral individuals Infection macaque mathematical model nasal passages nose and throat Older older patients parameter Parameter estimation SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus titre viral kinetics virus [DOI] 10.1098/rsos.202345 PMC 바로가기 [Article Type] Mathematics
Regular testing of asymptomatic healthcare workers identifies cost-efficient SARS-CoV-2 preventive measures무증상 의료 종사자에 대한 정기 테스트를 통해 비용 효율적인 SARS-CoV-2 예방 조치 확인Research Article Published on 2021-11-052022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] Asymptomatic Cohort cohort study Community community infection COVID-19 infection COVID-19 pandemic effective explained healthcare Healthcare professional healthcare professionals Healthcare system healthcare worker Healthcare workers hospital identify implementation incidence Infection maintain mathematical mathematical model nosocomial Nosocomial transmission observation performed preventive measure Protecting protocol Regular risk of infection SARS-CoV-2 SARS-CoV-2 transmission Transmission were used [DOI] 10.1371/journal.pone.0258700 PMC 바로가기 [Article Type] Research Article
Successive waves of COVID 19: confinement effects on virus-prevalence with a mathematical modelResearch Published on 2021-10-302022-10-31 Journal: European Journal of Medical Research [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome addition attacked China Chinese complex Confinement effects coronavirus country COVID COVID 19 decrease determine Effect Epidemic example finding First wave Germany globe incidence individual individuals information investigated Iran mathematical mathematical model nine number of infected outbreak pandemic parameter Prevalence Reproduction number Safe successive wave successive waves supplementary material the epidemic the median total population Transmission Transmission dynamics Treatment USA virus Virus-prevalence [DOI] 10.1186/s40001-021-00596-6 PMC 바로가기 [Article Type] Research
Divergent COVID-19 Disease Trajectories Predicted by a DAMP-Centered Immune Network ModelDAMP 중심 면역 네트워크 모델이 예측하는 다양한 COVID-19 질병 궤적Immunology Published on 2021-10-282022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] cellular Clinical data corticosteroid therapy COVID-19 COVID-19 disease DAMP danger signal disease trajectory generate hospitalized COVID-19 patients Hypothesis immune response Inflammation initial viral load manifestation mathematical mathematical model memory Mild Model moderate molecular network neutralizing antibody parameters pathogen-associated molecular pathogenic predict Protective reflected response SARS-CoV2 severe COVID-19 disease severe disease shifting Signaling temporal dynamics type I interferon viral infections Viral load [DOI] 10.3389/fimmu.2021.754127 PMC 바로가기 [Article Type] Immunology
Epidemiological Predictive Modeling of COVID-19 Infection: Development, Testing, and Implementation on the Population of the Benelux UnionCOVID-19 감염의 역학 예측 모델링: 베네룩스 연합 인구에 대한 개발, 테스트 및 구현Public Health Published on 2021-10-282022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 변종, [키워드] approach Belgium Benelux calculated coronavirus coronavirus disease coronavirus disease-2019 country COVID-19 Deceased deep learning development Differential equations disease spread modeling Diseases Epidemic epidemiological Epidemiological model except for expected explained health system help include infected cases Infectious diseases information LSTM model Luxembourg mathematical model Mathematical models measure mechanism medical intervention memory mild case mild cases modeling Netherland Netherlands number of infected outbreak parameter per day Population position predict prognostic model Recurrent Neural Network Result SEIRD model Short-Term Memory Spread statistical susceptible Testing union variants variants of concern were used [DOI] 10.3389/fpubh.2021.727274 PMC 바로가기 [Article Type] Public Health