The regulation of the mitochondrial apoptotic pathway by glucocorticoid receptor in collaboration with Bcl-2 family proteins in developing T cellsT 세포 발달에서 Bcl-2 계열 단백질과 협력하여 글루코코르티코이드 수용체에 의한 미토콘드리아 세포 사멸 경로의 조절The Many Ways of Apoptotic Cell Death Published on 2016-11-262022-08-07 Journal: Apoptosis [Category] Biochemistry, [키워드] accumulated activated Activation active caspase-3 alternative Apoptosis apoptotic pathway apoptotic pathways apoptotic signaling association Bax BCL-2 Bcl-2 family Bcl-2 family protein Bcl-2 proteins Bcl-x Bim caspase-3 caspase-8 caspase-9 CD4 CD8 classical Combination cross-talk Cytochrome C demonstrated Dexamethasone early phase event genomic glucocorticoid Glucocorticoid hormone Glucocorticoid receptor glucocorticoid receptor (GR Glucocorticoids Hypothesis in vitro Interaction investigated involved mice Mitochondria mitochondrial mitochondrial accumulation mitochondrial apoptotic pathway mitochondrial translocation molecular non-genomic Non-genomic pathway offered pathway Pathways receptor regulate Regulation remained sensitivity Signaling Support T cell thymocyte Thymocyte apoptosis thymocytes treated Treatment [DOI] 10.1007/s10495-016-1320-8 PMC 바로가기 [Article Type] The Many Ways of Apoptotic Cell Death
Varicella zoster virus infection of human fetal lung cells alters mitochondrial morphologyArticle Published on 2016-10-012023-06-02 Journal: Journal of Neurovirology [Category] 두창, 홍역, [키워드] IE63 Mitochondria Mitochondria morphology Mitochondria swelling Varicella zoster virus. [DOI] 10.1007/s13365-016-0457-0 PMC 바로가기
Is cancer a severe delayed hypersensitivity reaction and histamine a blueprint?Perspective Published on 2016-08-232023-08-30 Journal: Clinical and Translational Medicine [Category] E형 간염, [키워드] aging allergy Angiogenesis bioenergetics Branched amino acids Cancer Fetal growth Histamine hypersensitivity Immune-privileged and immune-responsive tissues Mitochondria Placenta Taurine Yin and Yang of inflammation [DOI] 10.1186/s40169-016-0108-3 PMC 바로가기 [Article Type] Perspective
Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia글리신과 엽산은 선천적 철모구성 빈혈의 모델을 개선합니다.Research Article Published on 2016-01-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 5-Ala 5-aminolevulinic acid addition Anemia anemic autosomal recessive biosynthetic pathway Blood blood cell Blood Transfusion Cell congenital congenital sideroblastic anemia derivative determine downstream effective exogenous glycine exogenously family member folate glycine glycine cleavage system Hem25 heme heme biosynthetic pathway heme synthesis hemoglobin homolog humans identify inherited anemia inherited anemias iron iron chelation knowledge metabolite Mitochondria mitochondrial mitochondrial glycine importer mitochondrial glycine importers mitochondrial glycine transporter mitochondrial glycine transporters Model molecular Mutation Patient precursors Protein red blood cell red blood cells required restore hemoglobin level restore hemoglobin levels Safe sideroblastic anemia Sideroblastic anemias SLC25 SLC25A38 synthesis the disease Tolerability Treatment Vitamin while yeast yeast cell yeast cells Ymc1 zebrafish [DOI] 10.1371/journal.pgen.1005783 PMC 바로가기 [Article Type] Research Article
Mitochondrial reactive oxygen species modulate innate immune response to influenza A virus in human nasal epitheliumArticle Published on 2015-07-012023-06-24 Journal: Antiviral Research [Category] 신종인플루엔자, [키워드] influenza A virus interferon-stimulated genes Mitochondria Reactive oxygen species. [DOI] 10.1016/j.antiviral.2015.04.011 PMC 바로가기
Only One Isoform of Drosophila melanogaster CTP Synthase Forms the CytoophidiumDrosophila melanogaster CTP Synthase의 단 하나의 Isoform이 Cytoophidium을 형성합니다Research Article Published on 2013-02-142022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addition ATP ATP synthase Author Bacteria biogenesis biological processe biological processes block Cell cell types cells conserved cytoplasm demonstrated different disrupt disrupting dissect distribution DNA and RNA domain Drosophila Drosophila melanogaster ectopic expression embryos energy metabolism enzyme example expression expression profiles form growth human cells identify independent induce isoform locus metabolism Mitochondria mutants Mutation nucleotide nucleotides nucleus organism overexpression provide shown Structure subcellular distribution subcellular structure Synthase synthase gene transcript while yeast [DOI] 10.1371/journal.pgen.1003256 PMC 바로가기 [Article Type] Research Article