Humoral response and breakthrough infections with SARS-CoV-2 B.1.617.2 variant in vaccinated maintenance hemodialysis patients예방 접종을 받은 유지 혈액 투석 환자에서 SARS-CoV-2 B.1.617.2 변이체에 의한 체액 반응 및 돌발성 감염Observational Study Published on 2022-06-012022-09-11 Journal: Journal of Nephrology [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 30-Day mortality 95% CI all-cause mortality analysed antibody B.1.617.2 BNT162b2 BNT162b2 vaccine Breakthrough COVID-19 infection Breakthrough infection caused clinical outcomes Control control group COVID-19 COVID-19 case COVID-19 infection Critical disease declining delta variant dose Effectiveness Hematological malignancies Hemodialysis Hospitalization humoral Humoral response Immunosuppression Immunosuppressive treatment Infection investigated maintenance Maintenance hemodialysis morbidity and mortality Mortality mortality rate nosocomial occur occurred Odds ratio outcome overall mortality Patient patients Pfizer-BioNTech required response to vaccination retrospective risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 variant SARS-CoV-2 variants significantly higher source of infection Spike protein study group Treatment vaccination Vaccine variant [DOI] 10.1007/s40620-022-01245-9 PMC 바로가기 [Article Type] Observational Study
High dose melatonin as an adjuvant therapy in intubated patients with COVID-19: A randomized clinical trialResearch article Published on 2022-06-012022-10-05 Journal: Journal of Taibah University Medical Sciences [Category] 임상, [키워드] adjuvant therapy Affect age anti-inflammatory agent C-reactive protein (CRP changes in complications conducted control group COVID-19 COVID-19 pandemic Critically ill patient CRP CRP levels decrease deviation dose double-blinded enrolled evaluated groups High-dose Inflammation intensive care Intervention intervention group Intubated intubated patient Invasive mechanical ventilation mechanical ventilation melatonin Mortality mortality rate objective outcome outcomes Oxygenation Patient patients older patients with COVID-19 per day Placebo Platelet randomized clinical trial Result SARS-COV-2 infection significant difference the mean the SARS-CoV-2 virus therapy Treatment with COVID-19 [DOI] 10.1016/j.jtumed.2022.04.012 [Article Type] Research article
Clinical Characteristics of Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19Observational Study Published on 2022-06-012022-10-05 Journal: Journal of stroke and cerebrovascular diseases : t [Category] 임상, [키워드] Against age analyzed arteries Atherosclerosis clinical Clinical characteristics clinical presentation connection COVID-19 COVID-19 negative demographic characteristics determine discharge examined group Ischemic Ischemic Stroke male material mechanism Mortality mortality rate no significant difference Observational cohort study outcome pandemic Patient patients patients hospitalized positive risk factor Risk factors significant difference stroke the patient the vaccine vaccinated against COVID-19 vaccination Vaccines [DOI] 10.1016/j.jstrokecerebrovasdis.2022.106483 PMC 바로가기 [Article Type] Observational Study
Seroprevalence of COVID-19 in Riyadh city during the early increase of COVID-19 infections in Saudi Arabia, June 2020Research article Published on 2022-06-012022-10-05 Journal: Saudi Journal of Biological Sciences [Category] 치료기술, [키워드] acute infections acute respiratory syndrome Asymptomatic blood donor Blood donors caused collected Complication coronavirus COVID-19 COVID-19 infection ELISA enzyme-linked immunosorbent evaluate evaluated global pandemic healthy blood donor highlight hospital Mild molecular mortality rate National non-COVID-19 patient pandemic Pandemics Patient Population populations positive sample reported SARS-CoV-2 Saudi Arabia SEROLOGICAL STUDY serological surveillance Seroprevalence serum sample virus spread [DOI] 10.1016/j.sjbs.2022.103282 [Article Type] Research article
Factors associated with SARS-CoV-2 antibody titers and prognosis of breakthrough infection in hemodialysis patients혈액투석 환자에서 SARS-CoV-2 항체가 및 돌발성 감염 예후와 관련된 인자Article Published on 2022-06-012022-09-12 Journal: Clinical and experimental nephrology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age Antibody titer association Breakthrough infection comparison Control control group controls Coronavirus disease 2019 COVID-19 COVID-19 patient develop Efficacy Factor Hemodialysis Hospitalization independent investigated Laboratory LDH mortality rate multivariable neutralization no significant difference Patient Prognosis regression analysis SARS-CoV-2 antibody severity severity of COVID-19 significantly significantly lower smoker smoking threshold vaccination Vaccine with COVID-19 [DOI] 10.1007/s10157-022-02188-y PMC 바로가기 [Article Type] Article
Cardiopulmonary predictors of mortality in patients with COVID-19: What are the findings?Research article Published on 2022-06-012022-10-05 Journal: Archives of cardiovascular diseases [Category] COVID19(2023년), SARS, 바이오마커, [키워드] 95% CI 95% confidence interval association cardiac injury Characteristics clinical collected Computed tomography Concentration consecutive patient coronavirus disease COVID-19 CT score Deceased determine Electrocardiography groups haematological malignancy identify independent predictor initial Injury Kaplan-Meier analysis Laboratory Mortality mortality rate Odds ratio Patient patients with COVID-19 predictor pulmonary disease Result severity significantly shorter ST depression subgroups survival troponin was performed with COVID-19 [DOI] 10.1016/j.acvd.2022.04.008 [Article Type] Research article
Comparison of COVID-19 outcomes in patients with Type 1 and Type 2 diabetes: A systematic review and meta-analysisReview article Published on 2022-06-012022-10-05 Journal: Diabetes & metabolic syndrome [Category] 임상, [키워드] age all-cause mortality rate Analysis approach assessment Clinical outcome Comorbidities Controlled trial COVID-19 COVID-19 patient diabete diabetes Diabetic disease severity eligible evaluate Evidence FIVE for inclusion Google group heterogeneous Hospitalization individual log Meta-analysis Mortality mortality rate no significant difference non-randomized observational study outcome outcomes Patient Prognosis Quality random-effect RCTs reported Research Result Sample size searched shown subject systematic review Total trials Type Type 1 diabetes mellitus type 2 diabetes Type 2 diabetes melltitus was used Web of Science [DOI] 10.1016/j.dsx.2022.102512 [Article Type] Review article
Abuse of amantadine in poultry may be associated with higher fatality rate of H5N1 infections in humansArticle Published on 2022-06-012023-06-22 Journal: Journal of medical virology [Category] 조류인플루엔자, [키워드] amantadine H5N1 L26I/V27A mutation linear correlation mortality rate [DOI] 10.1002/jmv.27664
Lung targeted liposomes for treating ARDSARDS 치료를 위한 폐 표적 리포솜Article Published on 2022-06-012022-09-11 Journal: Journal of controlled release : official journal o [Category] 치료제, [키워드] accumulate accumulation acute respiratory distress acute respiratory distress syndrome Administered administration alveolar approach ARDS BAL Bronchoalveolar lavage C57BL/6 characterized combined treatment COPD COVID-19 COVID-19 infections cysteine cytokine secretion distal DPPC drug Efficiency encapsulation endotracheal exhibited Gas exchange Hypoxemia IL-1β IL-6 impair infections Inflammation Inflammatory marker inflammatory markers intravenous intravenously lipid composition Lipid nanoparticles lipopolysaccharide Liposome lung lung damage Lung diseases lung disorders lung endothelial lung epithelial Lung inflammation Lungs Macrophage macrophages marker medication Methylprednisolone mice mortality rate mortality rates MPS mucolytic agent Mucus N-acetyl cysteine NAC nanoparticle Nanotechnology nitric oxide outcome Patient penetration provided pulmonary reached reduce reducing Region respiratory respiratory distress Respiratory distress syndrome secretion steroid syndrome therapeutic therapeutic effect therapeutic efficacy TNFα Treatment Treatment outcome were assessed [DOI] 10.1016/j.jconrel.2022.03.028 PMC 바로가기 [Article Type] Article
Artesunate, imatinib, and infliximab in COVID-19: A rapid review and meta-analysis of current evidenceCOVID-19의 Artesunate, imatinib 및 infliximab: 현재 증거에 대한 신속한 검토 및 메타 분석Review Published on 2022-06-012022-09-12 Journal: Immunity, Inflammation and Disease [Category] COVID19(2023년), SARS, 진단, [키워드] 95% confidence interval acute respiratory syndrome artesunate clinical benefit clinical trial Cochrane Library collaboration conducted control group coronavirus coronavirus disease COVID-19 COVID-19 patients database effective Efficacy and safety eligible Evidence favor Google Scholar hospital discharge Imatinib infliximab information International medication Meta-analysis mortality rate no significant difference patients with COVID-19 risk Safe screened significant difference solidarity survival the patient therapeutic intervention therapeutic interventions Trial two group vaccination was performed were used WHO [DOI] 10.1002/iid3.628 PMC 바로가기 [Article Type] Review