Quinoline Containing Side-chain Antimalarial Analogs: Recent Advances and Therapeutic Applicationarticle Published on 2020-12-312024-09-01 Journal: Current Topics in Medicinal Chemistry [Category] 말라리아, [키워드] Antiplasmodial activity Chloroquine cytotoxicity P. falciparum quinoline β-HI activity. [Article Type] article
Plasmodium falciparum multidrug resistance gene-1 polymorphisms in Northern Nigeria: implications for the continued use of artemether-lumefantrine in the region북부 나이지리아의 플라스모디움 팔시파룸 다제내성 유전자-1 다형성: 이 지역에서 아르테메터-루메판트린의 지속적인 사용에 대한 시사점Research Published on 2020-11-302024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drug resistance haplotypes P. falciparum Pfmdr1 single nucleotide polymorphisms [DOI] 10.1186/s12936-020-03506-z PMC 바로가기 [Article Type] Research
Identity-by-descent with uncertainty characterises connectivity of Plasmodium falciparum populations on the Colombian-Pacific coast불확실성이 있는 혈통별 신원 확인은 콜롬비아 태평양 연안에 있는 Plasmodium falciparum 개체군의 연결성을 특징짓습니다.Research Article Published on 2020-11-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] Accessibility accounted analyses Analysis approach coast collected component components confidence interval Confidence intervals connectivity descent disease disease control distance ecological epidemiological studies Epidemiological study Epidemiology estimate event FIVE fraction Fractions Frequency genetic data Genotype greater group Hypothesis IBD identify identity implication include Interpretation Intervention knowledge malaria malaria parasite malaria parasites methodological monoclonal organism Organisms P. falciparum parasite parasites Plasmodium Plasmodium falciparum Plasmodium falciparum malaria Population populations presenting Previous studies promote recent required separated Space statistically threshold thresholds Transmission whole genome sequence [DOI] 10.1371/journal.pgen.1009101 PMC 바로가기 [Article Type] Research Article
Sex-based differences in clearance of chronic Plasmodium falciparum infection성별에 따른 만성 플라스모디움 팔시파룸 감염의 제거 차이Article Published on 2020-10-272024-08-11 Journal: eLife [Category] 말라리아, [키워드] Amplicon deep sequencing asymptomatic malaria infection Duration of infection Molecular epidemiology P. falciparum sex-based differences [DOI] 10.7554/eLife.59872 PMC 바로가기
Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell Activation and Course of Disease급성 열대열 말라리아와 비교한 COVID-19 감염의 공동 억제 수용체 발현 분석: LAG-3 및 TIM-3은 T 세포 활성화 및 질병 경과와 상관관계가 있습니다Immunology Published on 2020-08-262022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, 말라리아, [키워드] Activation acute COVID-19 B cell response BTLA cause caused CCR7 CD226 CD38 CD4 CD45RO CD69 CD8 characterized co-expression Coronavirus disease 2019 COVID-19 COVID-19 patient disease course effector cell elevated Express expression expression pattern Frequency healthy controls HLA-DR hyperinflammation Hypothesis immune immune activation immune dysfunction Immunoglobulin implicated induce infected patient Infection inhibitory receptor LAG-3 limit malaria Mild novel SARS-CoV-2 virus outcome P. falciparum pathology Patient PBMC PD-1 PD1 Plasmodium falciparum Plasmodium falciparum malaria populations pro-inflammatory cytokine rapid normalization receptor SARS-CoV-2 SARS-CoV-2 patient severe disease course T cell T cells T-cell thought TIGIT TIM-3 transcription factor upregulation variety viral infection virus [DOI] 10.3389/fimmu.2020.01870 PMC 바로가기 [Article Type] Immunology
Emergence of Undetectable Malaria Parasites: A Threat under the Radar amid the COVID-19 Pandemic?감지할 수 없는 말라리아 기생충의 출현: 코로나19 팬데믹 속에서 감지되지 않는 위협?Perspective Piece Published on 2020-08-162022-10-28 Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, MERS, SARS, 말라리아, [키워드] Antigen COVID-19 COVID-19 pandemic Critical dependent on Diagnosis diagnostic test emergence evade false-negative genes encoding identify lack malaria overlap P. falciparum pandemic parasite Perspective Plasmodium falciparum Protein Rapid RDT RDTs Surveillance Symptom threat Transmission [DOI] 10.4269/ajtmh.20-0467 PMC 바로가기 [Article Type] Perspective Piece
Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults말라리아 백신 연구의 단백질체 전반 분석이 탄자니아 성인에서 개인화된 체액 면역 프로필을 밝혀냅니다.Article Published on 2020-07-142024-08-11 Journal: eLife [Category] 말라리아, [키워드] Controlled human malaria infection humoral immune response P. falciparum PfSPZ Vaccine protein microarray [DOI] 10.7554/eLife.53080 PMC 바로가기
Association of cerebral malaria and TNF-α levels: a systematic review뇌 말라리아와 TNF-α 수치의 연관성: 체계적 검토Research Article Published on 2020-06-232024-08-11 Journal: BMC Infectious Diseases [Category] 말라리아, [키워드] cerebral malaria malaria P. falciparum systematic review TNF-α [DOI] 10.1186/s12879-020-05107-2 PMC 바로가기 [Article Type] Research Article
Influx of diverse, drug resistant and transmissible Plasmodium falciparum into a malaria-free setting in Qatar다양하고 약물 저항성이 있으며 전염 가능한 플라스모디움 파르시파룸의 카타르 말라리아 없는 지역으로의 유입Research Article Published on 2020-06-152024-08-11 Journal: BMC Infectious Diseases [Category] 말라리아, [키워드] Gametocytes Gulf cooperation council (GCC) countries Imported malaria Malaria elimination P. falciparum Qatar [DOI] 10.1186/s12879-020-05111-6 PMC 바로가기 [Article Type] Research Article
Stochastic bond dynamics facilitates alignment of malaria parasite at erythrocyte membrane upon invasion확률적 결합 역학은 침입 시 말라리아 기생충이 적혈구 막에 정렬되도록 돕습니다.Article Published on 2020-05-182024-08-11 Journal: eLife [Category] 말라리아, [키워드] Cell adhesion malaria P. falciparum parasite alignment red blood cell Simulation [DOI] 10.7554/eLife.56500 PMC 바로가기