Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteasesReview Published on 2016-12-212024-09-04 Journal: World journal of gastroenterology [Category] 대상포진, [키워드] inflammatory bowel diseases irritable bowel syndrome protease inhibitors Proteases Proteinase-activated receptors visceral hypersensitivity Visceral pain [DOI] 10.3748/wjg.v22.i47.10275 PMC 바로가기 [Article Type] Review
Sociodemographic and clinical factors associated with the preference between NNRTIs and PIs for the initial treatment of HIV infection: Perfil-es studyArticle Published on 2016-10-012023-06-18 Journal: AIDS care [Category] B형 간염, [키워드] antiretroviral therapy (ART) HIV naïve non-nucleoside reverse transcriptase inhibitors protease inhibitors [DOI] 10.1080/09540121.2016.1173640
Protease inhibitor monotherapy for long-term management of HIV infection: a randomised, controlled, open-label, non-inferiority trialHIV 감염의 장기 관리를 위한 프로테아제 억제제 단독 요법: 무작위, 대조, 공개, 비열등성 시험Articles Published on 2015-09-142022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] 1:1 adverse event age Antiretroviral therapy ART baseline benefit block CD4 Cell Clinical management Clinical outcome clinical risk Combination combination treatment computer-generated Controlled darunavir defined drug drug resistance enrolled finding Frequency funding Genetic GRADE grade 3 HIV HIV infection inferiority inhibitor Intention intention to treat international standard Kaplan-Meier Kaplan-Meier analysis Lopinavir maintain management monotherapy non-inferiority non-inferiority margin non-inferiority trial number once daily Open-label parallel-group participant positive Pragmatic preserved Primary outcome Probability Protease inhibitor protease inhibitors public sector randomisation randomisation list randomised Randomly rebound Registered Ritonavir Serious Adverse Events shown Standard stratified suppressed the patient therapy toxic effects Treatment treatment failure Trial Viral Viral load virus [DOI] 10.1016/S2352-3018(15)00176-9 PMC 바로가기 [Article Type] Articles
Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4—The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)Article Published on 2015-06-192023-06-16 Journal: Bioorganic & Medicinal Chemistry [Category] MERS, [키워드] 3C-like protease broad-spectrum inhibitors coronavirus HKU4 HKU5 MERS Peptidomimetic compounds protease inhibitors SARS zoonotic reservoir [DOI] 10.1016/j.bmc.2015.06.039 PMC 바로가기 [Article Type] Article
Potential antivirals and antiviral strategies against SARS coronavirus infectionsReview Published on 2006-01-102023-06-16 Journal: Expert review of anti-infective therapy [Category] MERS, [키워드] coronavirus interferon monoclonal antibody protease inhibitors S protein SARS SARS-CoV inhibitors siRNA [DOI] 10.1586/14787210.4.2.291 PMC 바로가기 [Article Type] Review
Inhibition of SARS Coronavirus Infection In Vitro with Clinically Approved Antiviral DrugsResearch Published on 2004-04-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome agents Antiviral Antiviral agents antiviral drug antiviral drugs antivirals approved caused clinical testing clinically Compound coronavirus Coronavirus infection Culture cultured cell Cytopathic effect drug effective in vitro Infectious disease inhibition inhibitors interferon interferons investigated leukocyte neuraminidase inhibitors nucleoside analogs protease inhibitors SARS virus SARS-CoV SARS-CoV infection severe Severe acute respiratory syndrome Subtypes Support transcriptase treat Treatment was used [DOI] 10.3201/eid1004.030458 PMC 바로가기 [Article Type] Research