Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samples임상 샘플에서 SARS-COV-2의 검출 및 특성화를위한 나노 포어 메타 게놈 시퀀싱Research Article Published on 2021-11-182022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, 치료기술, 치료제, [키워드] Alpha Analysis assays characterization Classifier clinical sample clinical samples Complete concern Concordance COVID-19 pandemic Cycle threshold value diagnostic feasibility future work Gamma Genome less Lineage metagenomic sequencing Nanopore objective pathogen Pathogens PCR performed Phylogenetic Phylogenetic analysis positive Result RT-PCR SARS-CoV-2 sensitivity specificity specimen specimens Support variant variants Viral viral pathogens VoC was performed [DOI] 10.1371/journal.pone.0259712 PMC 바로가기 [Article Type] Research Article
COVID-19 prevalence among healthcare workers in Jakarta and neighbouring areas in Indonesia during early 2020 pandemicResearch Article Published on 2021-11-162022-10-28 Journal: Annals of Medicine [Category] COVID-19, SARS, [키워드] age all age groups Asymptomatic Clinical symptoms collected consequence Contact contaminated surfaces COVID-19 COVID-19 cases COVID-19 disease COVID-19 infection defined determine develop droplet effective strategy essential worker forms handling HCW Health healthcare healthcare service healthcare worker Healthcare workers high-risk population hospitalisation Indonesia Infection Jakarta majority median Medical doctor message Nurse outbreak pandemic Patient Personal protective equipment Pneumonia positive PPE Prevalence prevalence of COVID-19 PROTECT protocol Public Hospital reported Result retrospective cohort study risk of infection SARS-CoV-2 screened significantly lower specimens Surveillance swab specimen symptomatic tendency Transmission transmitted [DOI] 10.1080/07853890.2021.1975309 PMC 바로가기 [Article Type] Research Article
Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens임상 표본에서 SARS-COV-2 단백질을 탐지하는 도구로서 표적화 된 프로테오믹스Research Article Published on 2021-11-112022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 유전자 메커니즘, 치료기술, 치료법, 치료제, [키워드] abundance applied COVID-19 COVID-19 outbreak COVID-19 patient Critical Ct values detect diagnostics infected Vero E6 cells intensity limit of detection mass spectrometry methodology nasopharyngeal swabs nucleocapsid protein PCR peptides Protein proteomics Research SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins sensitivity specimen specimens sputum swabs tryptic peptide tryptic peptides Vero E6 VERO E6 cells Viral Viral protein Viral proteins Viral RNA [DOI] 10.1371/journal.pone.0259165 PMC 바로가기 [Article Type] Research Article
A rapid lateral flow immunoassay strip for detection of SARS‐CoV‐2 antigen using latex microspheresResearch Article Published on 2021-11-062022-10-30 Journal: Journal of Clinical Laboratory Analysis [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition age analyzed antibody Antigen antigen detection antigens applicability Bacterial infections cause clinical manifestation concealed conditions coronavirus COVID‐19 death decrease Detection limit Diagnosis diagnostic tests Dilution disadvantage disease stage EDC and NHS Efficiency Epidemic evaluated fixed Gender immune IMPROVE lateral flow immunoassay latex microspheres LFIA limit of detection Measures microsphere MOST offer Pneumonia point‐of‐care positive provide quarantine reproducibility Result SARS‐CoV‐2 SARS‐CoV‐2 antigen sensitivity Sensitivity and specificity specificity specimens stability tested the epidemic Vaccine virus visual method was determined was tested was used [DOI] 10.1002/jcla.24091 PMC 바로가기 [Article Type] Research Article
Comparative sensitivity evaluation for 122 CE-marked rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021Research Published on 2021-11-042022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] acute infection addressed CE mark Comparative COVID 19 eligible Europe evaluated exhibited Germany head-to-head evaluation Healthcare system identify independent less limit minimum MOST Numerous offered PCR performed quantification Rapid diagnostic test RDT Result SARS-CoV-2 SARS-CoV-2 antigen sensitivity Sensitivity and specificity sensitivity evaluation specimen specimens viral loads was used [DOI] 10.2807/1560-7917.ES.2021.26.44.2100441 PMC 바로가기 [Article Type] Research
Development of at-home sample collection logistics for large-scale seroprevalence studies대규모 혈청 유병률 연구를 위한 재택 검체 채취 물류 개발Research Article Published on 2021-11-042022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] Blood Blood samples condition COVID19 development effective effort Engagement enrolled Enrollment Massachusetts methodology pandemic participant Participants populations positive positive feedback Racial recruitment reported Result Safe serological serological survey specimens Study design while [DOI] 10.1371/journal.pone.0258516 PMC 바로가기 [Article Type] Research Article
Diagnostic Performance of Self-Collected Saliva Versus Nasopharyngeal Swab for the Molecular Detection of SARS-CoV-2 in the Clinical Setting임상 환경에서 SARS-CoV-2의 분자 검출을 위한 자가 채취 타액 대 비인두 면봉의 진단 성능Research Article Published on 2021-11-032022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] CT value acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 be positive can be used Care cause children clinic clinical collected Community community settings Contact coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 pandemic COVID-19 symptom COVID-19 symptoms criteria cycle threshold detect detection Diagnosis diagnosis of SARS-CoV-2 diagnostic difficulty discomfort enrolled equipment etiology feasibility groups Health Health care Health care worker health care workers indicated invasive investigated median meet nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs noninvasive NPs NPSs participant Participants Patient PCR performance positive presenting professionals qPCR quantitative PCR respiratory reverse transcription risk RT-qPCR Saliva saliva samples saliva specimen saliva specimens SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 viral load Screening sensitivity Sensitivity and specificity setting severe acute respiratory syndrome Coronavirus specimen specimens Spread symptom onset target gene Target genes the patient the WHO throat swab unit Viral was performed [DOI] 10.1128/Spectrum.00468-21 PMC 바로가기 [Article Type] Research Article
Self-Collected Oral Fluid and Nasal Swabs Demonstrate Comparable Sensitivity to Clinician Collected Nasopharyngeal Swabs for Coronavirus Disease 2019 Detection자가 수집 구강액 및 비강 면봉은 코로나바이러스 질병 2019 검출을 위해 임상의가 수집한 비인두 면봉과 유사한 감도를 나타냄Article Published on 2021-11-022022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 clinician coronavirus COVID19 detect detection nasal nasal swab Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens oral Participants performed pharyngeal pharyngeal. positive SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe acute respiratory syndrome Coronavirus specimen specimens swab specimen [DOI] 10.1093/cid/ciaa1589 PMC 바로가기 [Article Type] Article
Time-course evaluation of the quantitative antigen test for severe acute respiratory syndrome coronavirus 2: The potential contribution to alleviating isolation of COVID-19 patients중증급성호흡기증후군 코로나바이러스 2에 대한 정량적 항원 검사의 시간 경과 평가: COVID-19 환자 격리 완화에 잠재적 기여Observational Study Published on 2021-11-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 임상, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis Antigen automated Chain Reaction change characteristic conducted coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients cutoff point cutoff value detect determine diagnostic Diagnostic accuracy early stage examined facilitate indicated Infectivity infectivity assessment Inpatient Inpatients investigated Isolation late stage Lumipulse Mass screening Nasopharyngeal swab nasopharyngeal swab specimen Nasopharyngeal swab specimens Negative predictive value observational study patients polymerase chain polymerase chain reaction Positive predictive value Predictive value Quantitative Quantitative antigen test receiver operating characteristic retrospective ROC ROC analysis SARS-CoV-2 SARS-CoV-2 antigen scatterplot sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity specimen specimens stages was used [DOI] 10.1016/j.jiac.2021.08.015 PMC 바로가기 [Article Type] Observational Study
The COVID-19 Self-Testing through Rapid Network Distribution (C-STRAND) trial: A randomized controlled trial to increase COVID-19 testing in underserved populationsRandomized Controlled Trial Published on 2021-11-012022-10-05 Journal: Contemporary clinical trials [Category] SARS, 임상, [키워드] 1:1 affected approach clinical clinical trial clinical trials close contact Cohort cohort study Community Contact COVID-19 COVID-19 pandemic COVID-19 testing Critical determine distribution Efficacy effort eligible Health index individuals with COVID-19 network novel pandemic participant Philadelphia Population populations positive Primary outcome promote public health Randomized randomized clinical trial Randomized controlled trial Rapid receive seeking self-testing social networks specimens Testing [DOI] 10.1016/j.cct.2021.106585 PMC 바로가기 [Article Type] Randomized Controlled Trial