storm
[용어속성] Term
COVID-19: Underlying Adipokine Storm and Angiotensin 1-7 Umbrella
Immunology
[키워드] ACE2
acute respiratory syndrome
adipocyte
Adipokine
angiotensin
Angiotensin 1-7
association
coronavirus
CoV
COVID-19
deregulation
dysfunction
enzyme
explain
feature
greater
Health
high mortality rate
host cells
immune
Infection
infections
Inflammation
low expression
metabolic syndrome
obese patient
obesity
outbreak
pandemic
patients
Protein
receptor
Research
Respiratory failure
SARS-CoV
SARS-CoV-1
SARS-CoV-2
Scientific community
severity of COVID-19
Severity of infection
storm
syndrome
the SARS-CoV-2
therapeutic
type 2 diabete
UMBRELLA
unique
[DOI] 10.3389/fimmu.2020.01714 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.01714 PMC 바로가기 [Article Type] Immunology
Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm
Review
[키워드] ACE
ACE-2
ACE-2R
acute respiratory distress
Affect
Angiotensin converting enzyme-2
Antiviral
baseline
bind
cause
Cell
chronic inflammatory disease
common cold
coronavirus
COVID-19
current
CYP2D6
cytochrome P450
cytokine level
Cytokine storm
Cytokines
disease
Ebola
Enzymes
Genetic polymorphism
genetic polymorphisms
global pandemic
HIV
HO-1
Human immunodeficiency virus
include
Inflammatory response
kidney
Lungs
majority
manifested
medication
MERS
Middle East
mitochondrial dysfunction
organ
P450
patients with obesity
porphyrins
reactive oxygen specy
receptor
reservoir
resulting
RNA virus
role
SARS-CoV-2
Spread
storm
subsequent
syndrome
systemic inflammatory response
therapy
Treatment
upregulation
virus
white adipose tissue
[DOI] 10.3390/antiox9070636 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/antiox9070636 PMC 바로가기 [Article Type] Review
Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper
Immunology
[키워드] Acute kidney injury
acute respiratory distress
appear
approach
Autoimmunity
Biomarker
Cancer
caused
children
clinical
condition
COVID-19
COVID-19 patient
Critical
Critical care
Critically ill patient
Cytokine storm
Encephalitis
Evidence
Fatality rate
guidelines
help
high risk
Hyperinflammatory
identify
immune response
immunological mechanisms
immunotherapies
implicated
implication
infected with SARS-CoV-2
Kawasaki-like syndrome
large vessel
manifestation
modulate
multi-organ failure
Myocardial infarction
Neuroimmunology
Novel coronavirus
outcome
paper
Pathogenesis
pathway
position
prognostic
provide
renal
responsible
risk factor
SARS-CoV-2 infected patients
Sepsis
severe disease
storm
stroke
syndrome
the cytokine storm
therapeutic
therapeutic strategy
therapy
thromboembolic disease
understanding
Vasculitis
viral infections
worse prognosis
[DOI] 10.3389/fimmu.2020.01648 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.01648 PMC 바로가기 [Article Type] Immunology
Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
Immunology
[키워드] “cytokine storm”
acute respiratory syndrome
antimalarial
antimalarial agents
approach
cause
caused
cells
Concentration
contribute
coronavirus
coronavirus disease
Corticosteroids
COVID-19
COVID-19 patients
current
cytokine
Cytokine storm
death
effective
Evidence
IL-6
IL-6 inhibitor
immunoregulation
indicate
induce
infiltration
Intravenous immunoglobulin
lung tissue
Lymphocytes
Macrophage
Mortality
outbreak
pathogen
pathologic feature
patients with COVID-19
poor prognosis
pro-inflammatory
pro-inflammatory cytokines
programmed cell death
Protein
Safe
severely ill patient
storm
Strategy
the cytokine storm
Tocilizumab
Treatment strategies
[DOI] 10.3389/fimmu.2020.01708 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.01708 PMC 바로가기 [Article Type] Immunology
A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm
Short Report
[키워드] ACE
ACE2
activate
addition
addressed
Affect
affected
affecting
Analysis
analyzed
Atypical
BALF
blood pressure
blood vessel
bradykinin
Brain
Bronchoalveolar lavage fluid
cause
caused
Cell
changes in
China
clinical trial
clinician
collected
Combination
contribute
Control
cough
COVID-19
COVID-19 patient
COVID-19 patients
Critical
decrease
decreased expression
degrade
develop
disease
drug
effective
enzyme
expand
experiment
explain
Gene Expression
help
high temperature
Host
Human
Hyaluronic acid
identify
increases in
individual
induce
Inflammation
life-threatening
Lower
lung
lung cell
maintain
mechanism
Mild
molecular mechanism
multiple tissue
new virus
no symptom
opposite
outcome
oxygen uptake
Pain
Pathogenesis
Patient
patients with COVID-19
predicted
previous study
produced
provide
RAS
receptors
regulate
renin-angiotensin system
researcher
responsible
risk
SARS-CoV-2
sequence
severe symptom
shown
Spread
storm
Symptom
Symptoms
symptoms of COVID-19
the disease
the SARS-CoV-2 virus
therapeutic intervention
tissue
treat
treatments for COVID-19
turn
vascular dilation
vascular permeability
virus
was increased
were used
[DOI] 10.7554/eLife.59177 PMC 바로가기 [Article Type] Short Report
[DOI] 10.7554/eLife.59177 PMC 바로가기 [Article Type] Short Report
Atherosclerosis as Pathogenetic Substrate for Sars-Cov2 Cytokine Storm
Review
[키워드] absence
acute respiratory distress
acute respiratory syndrome
adverse outcomes
Affect
affecting
alveolar cells
ARDS
Atherosclerosis
atherosclerotic
binding
cardiovascular system
characterized
CHD
chronic inflammation
Complete
Concentration
Coronary heart disease
coronavirus
correlation
COVID-19
cytokine
Cytokines
damaged
Diabetes Mellitus
dysregulation
epithelial
Evolution
exacerbate
Factor
Factors
heart failure
high viral replication
hypertension
ICU
IL-1β
IL-6
immune system
Infection
Inflammation
intensive care
laboratory result
lung
multiorgan failure
Necrosis
outbreak
pathogenesis of SARS-CoV-2
pathological condition
Patient
patients
Predictive
pro-inflammatory
profile
progression
public health emergency
receptor ACE2
Region
reported
Reviewing
SARS-CoV-2
Sepsis
severe COVID-19 infections
severity
storm
substrate
suppress
susceptibility
Symptoms
syndrome
TNF-α
Treatment
viral replication
[DOI] 10.3390/jcm9072095 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/jcm9072095 PMC 바로가기 [Article Type] Review
Treatment of Severe COVID-19 with Tocilizumab Mitigates Cytokine Storm and Averts Mechanical Ventilation during Acute Respiratory Distress: A Case Report and Literature Review
Case Report
[키워드] “cytokine storm”
acute phase reactant
acute phase reactants
acute respiratory distress
administer
ARDS
blood draws
C-reactive protein
caused
chose
clinical status
COVID-19
cytokine
cytokine release
Cytokine release syndrome
Cytokine storm
D-dimer
declining
discharged
disease
distress
dosage
early treatment
Evidence
ferritin
highlight
Hydroxychloroquine
ICU
IL-6
IL-6 antagonist
IL-6 inhibitor
IL-6 inhibitors
IL-6 receptor
improvement
Inflammation
inhibitor
intubation
literature
male
management
Mechanical
mechanical ventilation
Mortality
oxygen support
pandemic
Patient
patients
patients with COVID-19
Prevent
progression
report
reported
respiratory
Respiratory Coronavirus
Respiratory disease
respiratory symptom
review
SARS-CoV-2
serum
severe COVID-19
storm
Support
syndrome
the patient
therapeutic
Therapeutic benefit
therapeutic strategy
therapy
Tocilizumab
treat
treated
Treatment
ventilator
Wuhan, China
[DOI] 10.3390/tropicalmed5030112 PMC 바로가기 [Article Type] Case Report
[DOI] 10.3390/tropicalmed5030112 PMC 바로가기 [Article Type] Case Report
A prospective, randomized, controlled study assessing vagus nerve stimulation using the gammaCore®-Sapphire device for patients with moderate to severe CoViD-19 Respiratory Symptoms (SAVIOR): A structured summary of a study protocol for a randomised controlled trial”
Letter
[키워드] 1:1
Acute respiratory failure
Administered
Admission
Adverse
age
Aneurysm
Antibiotics
atherosclerotic
baseline
blind
blood pressure
Brain
cardiovascular disease
carotid
cerebrovascular accident
cervical spine
chronic
clinical trial
Complete
congestive heart failure
Consent
control group
Controlled trial
Coronary artery disease
cough
COVID-19
criteria
current
cytokine
Cytokine storm
Day
decrease
Delay
Disabled
disease
dissemination
distress
dose
electrical
element
eligible
enrolled
evaluate
expected
Follow-up
Gender
growth
Healthcare provider
hemorrhage
history
hospital
hospital discharge
ICU admission
Informed
Initiation
interleukin
interleukin 6
Intervention
less
mechanical ventilation
mechanical ventilator
Mild
moderate
Mortality
Myocardial infarction
nerve stimulation
number
O2 Saturation
objective
occur
Older
open label
outcome
oxygen
Oxygen level
Oxygen therapy
parallel group
participant
Patient
patients with moderate
per day
persist
positive
prophylactically
protocol
pulmonary
randomisation
randomised
randomised controlled
randomised controlled trial
randomization
Randomized
recruited
recruitment
reduce
reduction
regimen
Registered
required
Research
respiratory
Respiratory failure
Sample size
Sapphire
saturation
second dose
secondary
severity
Shortness of breath
SOC
Spain
Standard
Standard of care
status
storm
stratified
study group
Study protocol
subject
supplemental oxygen
supplemental oxygen requirement
tested
trauma
Treatment
tumor necrosis factor
tumors
uncontrolled
Vague neurostimulation
Valencia
Ventilation
ventilatory support
website
women
[DOI] 10.1186/s13063-020-04486-w PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04486-w PMC 바로가기 [Article Type] Letter
Potential Treatments for COVID-19 Related Cytokine Storm – Beyond Corticosteroids
Immunology
[키워드] COVID-19
hemophagocytic lymphohistiocytosis
IL-6
Potential
ruxolitinib
storm
Tocilizumab
[DOI] 10.3389/fimmu.2020.01445 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.01445 PMC 바로가기 [Article Type] Immunology