Should We Delay the Second COVID-19 Vaccine Dose in Order to Optimize Rollout? A Mathematical Perspective롤아웃을 최적화하기 위해 두 번째 COVID-19 백신 접종을 연기해야 합니까? 수학적 관점Public Health Archive Published on 2022-01-242022-09-10 Journal: International Journal of Public Health [Category] MERS, SARS, 변종, [키워드] administer approach booster country COVID-19 COVID-19 vaccine daily dose Delay delta variant dose dose regimen doses Efficacy first dose followed by immunization schedule index Infectious disease less optimization problem pandemic public health question raise receiving reduced second second dose single dose the vaccine vaccination Vaccination strategy Vaccine vaccine doses variant [DOI] 10.3389/ijph.2021.1604312 PMC 바로가기 [Article Type] Public Health Archive
Mucosal Vaccines, Sterilizing Immunity, and the Future of SARS-CoV-2 Virulence점막 백신, 멸균 면역 및 SARS-COV-2 독성의 미래Review Published on 2022-01-192022-09-01 Journal: Viruses [Category] SARS, 진단, [키워드] animal reservoirs antigens BNT162b2 coin Coronaviruses COVID-19 Endemic Future hospital Human IgA IgG Immunity implication induce Infection intramuscular intranasal vaccine mRNA-1273 mucosal mucosal secretions mucosal vaccines Neutralizing Neutralizing antibodies neutralizing antibody Occurrence oral vaccines patients Prevent priming pros public health reservoirs respiratory respiratory virus respiratory viruses SARS-CoV-2 SARS-CoV-2 vaccine Spread sterilizing immunity systemic Transmission vaccination Vaccination strategy Vaccine vaccinees virulence viruses [DOI] 10.3390/v14020187 PMC 바로가기 [Article Type] Review
Antibody Responses to BNT162b2 Vaccination in Japan: Monitoring Vaccine Efficacy by Measuring IgG Antibodies against the Receptor-Binding Domain of SARS-CoV-2Research Article Published on 2022-01-192022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, COVID19(2023년), SARS, [키워드] acute respiratory syndrome age analyzed antibody antibody isotype antibody production Antibody Response BNT162b2 BNT162b2 vaccine cause clinical setting Cohort coronavirus coronavirus disease correlated correlation COVID-19 detect determine dose Efficacy enzyme enzyme-linked immunosorbent Factors female Gender high correlation hypertension IgA IgG IgG level IgM immunoassay individual individuals information Japan Japanese Laboratory levels of antibodies males mass vaccination MONITOR monitoring mRNA vaccine negative correlation Neutralizing activity of BNT162b2 powerful tool predict provide RBD reported response SARS-CoV-2 SARS-CoV-2 vaccination second dose second vaccination sera Serological assay significantly significantly higher the receptor-binding domain vaccinated individual vaccination Vaccination strategy Vaccine was measured were measured [DOI] 10.1128/spectrum.01181-21 PMC 바로가기 [Article Type] Research Article
Targeted vaccination and the speed of SARS-CoV-2 adaptation표적 백신 접종과 SARS-CoV-2 적응 속도Article Published on 2022-01-182022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptation Analysis consequence coronavirus country COVID-19 cumulative deaths determine effective epidemiological epidemiologically Evolutionary epidemiology expected faster Frequency Host increase individual involved Older proportion pros question raise reduce required SARS-CoV-2 second dose severe acute respiratory syndrome Coronavirus single dose speed Spread target the disease vaccinate vaccination Vaccination strategy Vaccine variant viral adaptation [DOI] 10.1073/pnas.2110666119 PMC 바로가기 [Article Type] Article
Patterns of neutralizing humoral response to SARS-CoV-2 infection among hematologic malignancy patients reveal a robust immune response in anti-cancer therapy-naive patients혈액 학적 악성 악성 환자들 사이에서 SARS-COV-2 감염에 대한 체액 반응을 중화시키는 패턴은 항암 치료-상대 환자에서 강력한 면역 반응을 나타낸다.Clinical Trial Published on 2022-01-182022-09-01 Journal: Blood Cancer Journal [Category] 임상, 진단, [키워드] analyzed anti-cancer treatment anti-SARS-CoV-2 humoral Chemotherapy COVID-19 cross-sectional cross-sectional study enhanced geometric geometric mean Haematological cancer Hematologic malignancy HM patient HM patients humoral IgG titers immune response Infection Infectious diseases lowest lymphoid malignancy Medical research natural infection neutralization titer Neutralizing Neutralizing activity Patient pattern PCR-confirmed Post-infection question raising receive receiving robust SARS-CoV-2 immunity SARS-COV-2 infection seroconversion rate seroconvert serum severe COVID-19 symptomatic symptomatic COVID-19 the patient therapy understanding Vaccination strategies Vaccination strategy Vaccine vulnerable population [DOI] 10.1038/s41408-022-00608-6 PMC 바로가기 [Article Type] Clinical Trial
B- and T-Cell Responses After SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis Receiving Disease Modifying Therapies: Immunological Patterns and Clinical ImplicationsClinical Trial Published on 2022-01-172022-10-04 Journal: Frontiers in Immunology [Category] 임상, 치료기술, [키워드] acute respiratory syndrome administration age and sex All the patient Analysis anti-S anti-S antibody Antibody detection Antibody titers B-lymphocyte blood lymphocyte count CD20 cell-mediated response characterized circulating clinical Cohort comparable coronavirus Coronavirus-2 correlation COVID COVID-19 disease dose effective enrolled evaluate fingolimod General population GraphPad Prism healthy donor help Humoral response IFN-gamma IGRA Immunological response increase in lymphocyte Modifying mRNA vaccine Multiple multiple sclerosis Natalizumab NK-cell Ocrelizumab Patient pattern peptide peptides peripheral Peripheral blood Population protective role raised reduced reduction reported response Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 vaccine sclerosis second dose severe COVID-19 Spread symptoms of COVID-19 T-cell T-cell Response T-cell responses T-lymphocyte Treatment Vaccination strategy Vaccine vaccine immunogenicity was performed were assessed while [DOI] 10.3389/fimmu.2021.796482 PMC 바로가기 [Article Type] Clinical Trial
Accessibility of COVID-19 Vaccination Centers in Germany via Different Means of TransportArticle Published on 2022-01-172022-10-30 Journal: Kn - Journal of Cartography and Geographic Information [Category] COVID-19, [키워드] Accessibility acute respiratory syndrome Against anticipated approach approval center comparable condition coronavirus COVID-19 COVID-19 pandemic COVID-19 vaccination dependent on Germany Government help National question Raster-based accessibility analysis Region reported SARS-CoV-2 Thünen-Accessibility model the mean Transport vaccination Vaccination strategy Vaccine widespread [DOI] 10.1007/s42489-021-00088-x PMC 바로가기 [Article Type] Article
Machine learning for emerging infectious disease field responsesArticle Published on 2022-01-102022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] age and gender analysed approach biomedical engineering Comorbidity COVID-19 pandemic demonstrated develop Disease progression Effect effective Emerging infectious disease global public health Health services healthcare healthcare facility Hospital admission identify imperative Infectious disease Infectious diseases Laboratory tests machine medical resource minor symptom mortality risk occurred outbreak Patient patients physician protective immunity public health raised response risk Risk factors Spread Vaccination strategy [DOI] 10.1038/s41598-021-03687-w PMC 바로가기 [Article Type] Article
Factors That Impact Acceptance of COVID-19 Vaccination in Different Community-Dwelling Populations in ChinaArticle Published on 2022-01-082022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI acceptance approved children China Community conducted COVID-19 COVID-19 vaccination Diseases effective Efficacy and safety Factor female Government Health status hospital Immunity immunization Impact IMPROVE indicated Influencing factors less male media medium MOST multi-level logistic regression National Health Commission parent participant Participants Population positive attitude questionnaire Questionnaires random effect receive recruited Shanghai vaccination Vaccination strategy Vaccine vaccine acceptance rate were used Zhejiang [DOI] 10.3390/vaccines10010091 PMC 바로가기 [Article Type] Article
Determinants of COVID-19 Vaccine Acceptance and Hesitancy: A Health Care Student-Based Online Survey in Northwest ChinaPublic Health Published on 2022-01-062022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] acceptance affecting Analysis association Binary logistic regression Care China concern Coverage COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine cross-sectional survey demographics determinant determine Effectiveness expand Factor Health healthcare Healthcare students high uptake identify Immunity immunization individual Infection information Juan less measure pandemic performed PROTECT Protective questionnaire receive rejection Side effect spread of COVID-19 survey survey platform the vaccine thought vaccinated individual vaccination Vaccination strategy Vaccine Vaccine acceptance Vaccine hesitancy vaccine hesitant was performed Wen [DOI] 10.3389/fpubh.2021.777565 PMC 바로가기 [Article Type] Public Health