Pemphigus—The Crux of Clinics, Research, and Treatment during the COVID-19 PandemicReview Published on 2021-10-282022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] approach autoantibody autoantigen Autoimmune disease Blister classical clinics COVID-19 COVID-19 infection desmoglein determine develop diagnostic discrepancy immunodermatology immunosuppressive effect lesion Manifestations mucosal other immunosuppressive agents Pathogenesis pathogenic autoantibody pathophysiological Patient pemphigus profile Proteins raised risk rituximab SARS-CoV-2 SARS-CoV-2 pandemic subtype Treatment use of corticosteroid vaccine response variant [DOI] 10.3390/biomedicines9111555 PMC 바로가기 [Article Type] Review
Does a lack of vaccine side effects correlate with reduced BNT162b2 mRNA vaccine response among healthcare workers and nursing home residents?Original Article Published on 2021-10-152022-10-28 Journal: Aging Clinical and Experimental Research [Category] COVID-19, MERS, SARS, [키워드] absence all subject anti-receptor-binding domain Anti-spike antibody Antibody titers appear BNT162b2 BNT162b2 mRNA vaccine Care clinician COVID-19 enrolled excluded Frequency greater healthcare healthcare worker help immunogenicity immunogenicity data incidence lack Linear regression model Local log-transformed log-transformed titer Mild mRNA vaccination much lower neutralizing titers nursing homes populations RBD reaction reactogenicity reduced reported Result SARS-CoV-2 severity Side effect Side effects significantly significantly lower statistically significant subject supplementary material systemic reactions systemic reactogenicity the vaccine trials vaccination Vaccine vaccine response [DOI] 10.1007/s40520-021-01987-9 PMC 바로가기 [Article Type] Original Article
Rapid development of analytical methods for evaluating pandemic vaccines: a COVID-19 perspectiveSpecial Report Published on 2021-10-142022-10-28 Journal: Bioanalysis [Category] COVID-19, MERS, SARS, [키워드] analytical tools assist attribute computational modeling COVID-19 COVID-19 pandemic COVID-19 vaccine dependent on develop highlight In vitro assay in vivo initial Mutation pandemic Perspective preclinical models predict provide Rapid SARS-CoV-2 Vaccine Vaccine design vaccine production vaccine response Viral protein virus viruses [DOI] 10.4155/bio-2021-0096 PMC 바로가기 [Article Type] Special Report
Toll-like Receptors in Viral EncephalitisReview Published on 2021-10-142022-10-28 Journal: Viruses [Category] COVID-19, [키워드] addition Affect Astrocyte astrocytes Cell cell differentiation CNS complex interplay condition consequence Encephalitis example expressed Flaviviridae function functional herpes simplex herpes viruses highlight immune stimulation immunodeficiency implication Infection infections Intervention knowledge less microglia neurite outgrowth Neuron neuronal neurons neurotropic Paramyxoviridae Rhabdoviridae stimulated subset syndrome TLR TLR signaling TLR stimulation Toll-like receptor Toll-like receptors vaccine response varicella viral encephalitis virus viruses [DOI] 10.3390/v13102065 PMC 바로가기 [Article Type] Review
Response to BNT162b2 mRNA COVID-19 vaccine among healthcare workers in Italy: a 3-month follow-up이탈리아 의료 종사자들의 BNT162b2 mRNA COVID-19 백신에 대한 반응: 3개월 추적 관찰Im - Original Published on 2021-10-122022-09-10 Journal: Internal and Emergency Medicine [Category] MERS, SARS, 치료기술, [키워드] administration Adverse adverse events anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody BNT162b2 BNT162b2 mRNA BNT162b2 vaccine COVID-19 COVID-19 vaccine cut-off Effectiveness event exceeded first dose focus Follow-up HCW HCWs healthcare worker Healthcare workers high risk hospital immunization immunoglobulins Infection investigated Italian Nasopharyngeal swab nasopharyngeal swabs nucleic acid offer participant Participants positive reactivity recipients reported Research response RT-PCR assay SARS-CoV-2 SARS-CoV-2 nucleic acid serology testing tested the vaccine Vaccine vaccine response [DOI] 10.1007/s11739-021-02857-y PMC 바로가기 [Article Type] Im - Original
COVID-19 and immune-mediated inflammatory diseases: effect of disease and treatment on COVID-19 outcomes and vaccine responsesReview article Published on 2021-10-012022-10-05 Journal: The Lancet Rheumatology [Category] 치료법, [키워드] collected COVID-19 COVID-19 pandemic cytokine inhibitors Diagnosis disease Diseases glucocorticoid high risk immune response Immune-mediated Immune-mediated inflammatory disease Immune-mediated inflammatory diseases Inflammatory Inflammatory arthritis Inflammatory bowel disease medication methotrexate outcome outcomes Patient reduced risk SARS-COV-2 infection SARS-CoV-2 vaccination severe COVID-19 Tolerability Treatment vaccination vaccine response [DOI] 10.1016/S2665-9913(21)00247-2 [Article Type] Review article
mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant80세 이상의 사람들에서 mRNA 백신 접종은 P.1 브라질 변이체의 교차 중화와 함께 SARS-CoV-2에 대한 강한 체액성 면역 반응을 유도합니다Research Article Published on 2021-09-292022-09-10 Journal: eLife [Category] SARS, 변종, 진단, [키워드] age antibody Antibody Response Antibody responses BNT162b2 BNT162b2 mRNA vaccine Brazil Cellular immune response cellular response Cellular responses correlated COVID-19 COVID-19 vaccination cross detectable Donor dual effective Efficacy Human humoral humoral immune response Humoral immunity Humoral response immune responses immunosenescence induce Infection Mortality mRNA vaccination mRNA vaccine neutralization neutralization titer neutralization titers Older P.1 P.1 variant Pfizer platform reduced remained risk factor SARS-CoV-2 SARS-COV-2 infection second vaccination sera serological Spike protein Spike-specific cellular immune responses These data trials vaccination Vaccine vaccine response vaccine responses variant Victoria [DOI] 10.7554/eLife.69375 PMC 바로가기 [Article Type] Research Article
Validation of the effectiveness of SARS-CoV-2 vaccines in older adults in “real-world” settingsCommentary Published on 2021-09-222022-10-30 Journal: Immunity & Ageing : I & A [Category] COVID-19, [키워드] adoptive immunotherapy aging approach COVID-19 develop Effectiveness Efficacy Longevity of vaccine response mAb mechanism Neutralizing neutralizing mAb offer Older older population reduced Regulation respond responders SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine severity T cell response vaccination Vaccine vaccine immunity vaccine response validation variant [DOI] 10.1186/s12979-021-00248-7 PMC 바로가기 [Article Type] Commentary
SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British ColumbiaSARS-CoV-2 혈청학: 브리티시컬럼비아에서 고처리량 화학발광 면역분석(CLIA) 플랫폼 및 현장 연구 검증Article Published on 2021-09-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 진단, 치료기술, [키워드] Abbott addition adjunct Antibody testing assays automated Care chemiluminescent immunoassay CLIA collected COVID-19 demonstrated diagnose diagnoses DiaSorin Disease prevalence Elecsy evaluated field Infection LIAISON molecular Negative predictive value Ortho Vitros outbreak Outbreak investigation outbreak investigations PCR PCR testing performed platform Positive predictive value positive predictive values post-symptom onset PPV predictive values Prevalence required Roche S1/S2 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing sensitivities sensitivity Sensitivity and specificity serologic serologic testing serology Siemen Siemens Specificities tested Total vaccine response validation validation study [DOI] 10.1016/j.jcv.2021.104914 PMC 바로가기 [Article Type] Article
Durability of antibody response to vaccination and surrogate neutralization of emerging variants based on SARS-CoV-2 exposure historySARS-COV-2 노출 이력에 기초한 신흥 변이체의 예방 접종 및 대리 중화에 대한 항체 반응의 내구성Comparative Study Published on 2021-08-302022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody antibody levels Antibody Response binding booster vaccination coronavirus COVID-19 infection Decline effective Effectiveness highlighting identify indication indications Infectious diseases Messenger RNA neutralization Neutralizing antibody response neutralizing antibody responses reduced respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus symptomatic the timing vaccination Vaccine vaccine doses vaccine response vaccine responses variant variants Viral viral infection Viral variants [DOI] 10.1038/s41598-021-96879-3 PMC 바로가기 [Article Type] Comparative Study