Evaluation of Commercially Available Viral Transport Medium (VTM) for SARS-CoV-2 Inactivation and Use in Point-of-Care (POC) TestingArticle Published on 2020-10-232022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] addition applied buffer conducted described determine diagnostic experiment inactivated inactivation incubated molecular non-infectious physically platform POC point-of-care protocol SARS-CoV-2 SARS-CoV-2 virus separated specimen Testing titre Transport viability viral inactivation virucidal virus VTM WHO World Health Organization [DOI] 10.3390/v12111208 PMC 바로가기 [Article Type] Article
Vulnerabilities of the SARS-CoV-2 Virus to Proteotoxicity—Opportunity for Repurposed Chemotherapy of COVID-19 InfectionPharmacology Published on 2020-10-092022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] activated antiviral activity arginine residue arginine residues bioinformatics caused cellular Concentration conserved coronavirus COVID-19 COVID-19 disease cysteine residue domain domains Doxorubicin drug effective vaccine Efficacy Evidence examined expected functional global pandemic glyoxalase inactivation Infection interactions MERS metabolite methylglyoxal Modification oxidative paclitaxel physiological system predicted produced producing proteome proteomics Quantitative reactive reactive oxygen specy residue ROS SARS-CoV SARS-CoV-2 selective susceptible targets the SARS-CoV-2 the spike protein therapeutic therapy Toxicity Treatment virucidal vulnerability [DOI] 10.3389/fphar.2020.585408 PMC 바로가기 [Article Type] Pharmacology
In Vitro Virucidal Effect of Intranasally Delivered Chlorpheniramine Maleate Compound Against Severe Acute Respiratory Syndrome Coronavirus 2Allergy/Immunology Published on 2020-09-172022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Against analysis of variance ANOVA Antiviral antiviral activity Antiviral effect average calculated CCID Cell culture Chlorpheniramine chlorpheniramine maleate clinical trials Compound Contact Control coronavirus coronavirus 2 COVID-19 COVID-2019 CPM determine dose Effect effective endpoint titer genome sequence GraphPad Prism hospitalized patient Hydroxychloroquine in vitro independent infected cells Infection Influenza initial intranasal intranasally Log reduction medication MERS-CoV Middle East Mild-to-moderate nasal Nasal spray novel coronavirus disease outbreak pandemic Patient placebo-controlled study Randomized reduced reduction in replicate respiratory respiratory syndrome coronavirus responsible Result Safe SARS-CoV SARS-CoV-2 similarity Standard deviation statistically significant strain tested Treatment USA-WA1/2020 Vero Viral load virucidal virus was tested [DOI] 10.7759/cureus.10501 PMC 바로가기 [Article Type] Allergy/Immunology
In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2Research Published on 2020-09-092022-10-28 Journal: Virology Journal [Category] COVID-19, SARS, [키워드] 229E Antiviral antivirals Case fatality rate Cell Cell culture cell lines common cold common cold coronavirus common cold Coronaviruses comparable Concentration concentrations Contact coronavirus Coronaviruses CoV COVID-19 CoVs Dilution droplet Echinacea effective evaluate evaluated Gastrointestinal symptom HCoV-229E highly pathogenic Human in vitro inactivated Infection infections inhibit investigated MERS MERS-CoV Middle East mild respiratory morbidity and mortality nasal epithelium natural infection observé outbreak Post-infection prevention prophylactic treatment Prophylaxis protective effect respiratory respiratory epithelium Result SARS-CoV-1 SARS-CoV-2 similarities thought Treatment virucidal virus particle virus propagation zoonotic [DOI] 10.1186/s12985-020-01401-2 PMC 바로가기 [Article Type] Research
Combating SARS-CoV-2: leveraging microbicidal experiences with other emerging/re-emerging virusesMicrobiology Published on 2020-09-082022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] acute respiratory syndrome aerosol approach China city coronavirus disease disrupting dissemination Ebola virus Effectiveness Enterovirus D68 example Hantaan virus hygiene Infection Infection prevention information International Intervention Lassa virus mechanism MERS-CoV Microbicides Nipah virus public health route of infection SARS-CoV SARS-CoV-2 SFTSV Spread survival Transmissibility Travel virucidal virus viruses Wuhan zoonotic [DOI] 10.7717/peerj.9914 PMC 바로가기 [Article Type] Microbiology
Control Measures for SARS-CoV-2: A Review on Light-Based Inactivation of Single-Stranded RNA VirusesReview Published on 2020-09-082022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] blood products blue Blue light can be used circumvent Control dependent on Efficacy Efficiency family Coronaviridae Future improvement inactivation measure parameter Red red light required review RNA SARS-CoV-2 single-stranded RNA virus Single-stranded RNA viruses ssRNA susceptibility ultraviolet viral inactivation virucidal virus was reduced [DOI] 10.3390/pathogens9090737 PMC 바로가기 [Article Type] Review
Simple, Low-Cost and Long-Lasting Film for Virus Inactivation Using Avian Coronavirus Model as ChallengeArticle Published on 2020-09-042022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Antiviral caused challenge Contact contaminated surface coronavirus COVID-19 infection detergent Direct dose Efficacy expected film flammable inactivated inactivation infective maintain Model morphologically polystyrene Population populations quantification RNA virus RT-qPCR sanitization SARS-CoV-2 shown simple Spread spread of COVID-19 virucidal virucide virus virus infectivity was determined was used [DOI] 10.3390/ijerph17186456 PMC 바로가기 [Article Type] Article
Did granny know best? Evaluating the antibacterial, antifungal and antiviral efficacy of acetic acid for home care proceduresResearch Article Published on 2020-08-262022-10-28 Journal: BMC Microbiology [Category] Coronavirus, MERS, [키워드] acetic acetic acid Antifungal antimicrobial antimicrobial effect Antiviral antiviral efficacy C. albican Care Complete Concentration COVID-19 Domestic hygiene dosage E. coli Efficacy Evaluating groups Immunocompromised investigated logarithmic reduction microorganism microorganisms MRSA P. aeruginosa Pandemics pneumoniae pregnant reduction Result Test vaccinia variety virucidal virus viruses was obtained [DOI] 10.1186/s12866-020-01948-8 PMC 바로가기 [Article Type] Research Article
Light-based technologies for management of COVID-19 pandemic crisisArticle Published on 2020-08-192023-06-15 Journal: Journal of photochemistry and photobiology. B, Bio [Category] MERS, SARS, [키워드] germicidal photobiology Photobiomodulation photodynamic Photoinactivation ultraviolet virucidal [DOI] 10.1016/j.jphotobiol.2020.111999 PMC 바로가기
Hard Nanomaterials in Time of Viral PandemicsReview Published on 2020-07-152023-06-14 Journal: ACS Nano [Category] MERS, SARS, [키워드] Antiviral biomaterials immune system Nanoparticles phototherapy surface chemistry Vaccine virucidal [DOI] 10.1021/acsnano.0c04117 PMC 바로가기 [Article Type] Review