Rapid review for the anti-coronavirus effect of remdesivirReview Published on 2020-01-012023-07-05 Journal: Drug discoveries & therapeutics [Category] SARS, [키워드] COVID-19 Effect Remdesivir Safety. SARS-CoV-2 [DOI] 10.5582/ddt.2020.01015 PMC 바로가기 [Article Type] Review
SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New CoronavirusArticle Published on 2020-01-012023-07-05 Journal: Current medicinal chemistry [Category] SARS, [키워드] antiviral drugs coronavirus COVID-19 Favipiravir Hydroxychloroquine Lopinavir Remdesivir Ritonavir. SARS-CoV-2 [DOI] 10.2174/0929867327666200416131117 PMC 바로가기
Shape-based Machine Learning Models for the Potential Novel COVID-19 Protease Inhibitors Assisted by Molecular Dynamics SimulationArticle Published on 2020-01-012023-07-05 Journal: Current topics in medicinal chemistry [Category] SARS, [키워드] COVID-19 COVID-19 protease inhibitors machine learning molecular docking Moleculardynamics simulation nCorv-EMBS. Remdesivir Shape-based ML [DOI] 10.2174/1568026620666200704135327 PMC 바로가기
Novel Drugs Targeting the SARS-CoV-2/COVID-19 MachineryArticle Published on 2020-01-012023-07-05 Journal: Current topics in medicinal chemistry [Category] SARS, [키워드] 3CLpro camostat coronavirus SARS-CoV-2 COVID-19 Remdesivir RNA polymerase S protein α-Ketoamides. [DOI] 10.2174/1568026620999200517043137 PMC 바로가기
Review of current clinical management guidelines for COVID-19 with special reference to IndiaReview Published on 2020-01-012023-07-05 Journal: Drug discoveries & therapeutics [Category] SARS, [키워드] convalescent plasma coronavirus disease 19 Dexamethasone Hydroxychloroquine Remdesivir tocilizumab. [DOI] 10.5582/ddt.2020.03059 PMC 바로가기 [Article Type] Review
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading ExoribonucleaseResearch Article Published on 2018-03-062022-10-29 Journal: mBio [Category] Coronavirus, SARS, [키워드] 50% effective concentration absence acute respiratory syndrome animal model Antiviral Antiviral agents antiviral resistance approved attenuate Combined Concentration conserved coronavirus coronavirus CoV CoV infection CoVs decrease development effective Efficacy ExoN proofreading Exoribonuclease expand GS-5734 human infections humans impair in vitro include Infection infections inhibit interfere Mediated MERS-CoV MHV Middle East murine hepatitis virus mutant Mutation nontoxic Nsp12 nsp14 exoribonuclease nucleoside nucleoside analogs nucleotide prodrug overcome pandemic parent nucleoside passage Pathogenesis phenotype polymerase Proofreading PROTECT Remdesivir reported residue respiratory syndrome coronavirus RNA polymerases SARS-CoV selected severe disease significantly more Substitution therapeutic treat viral fitness virulence virus wild-type zoonotic CoV [DOI] 10.1128/mBio.00221-18 PMC 바로가기 [Article Type] Research Article