Human Coronavirus NL63 Open Reading Frame 3 encodes a virion-incorporated N-glycosylated membrane proteinResearch Published on 2010-01-152022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] accessory protein addition Alpha Amino acid Analysis antiserum C-terminus Cell conserved coronavirus Coronaviruses cytosolic detected digestion ENCODE ERGIC Evidence expression Extracellular FLAG-tagged fluorescence microscopy Frame function Golgi Huh-7 cell Human human coronavirus immunofluorescence In-vitro Infected lysosomal membrane membrane protein N-terminus NL63 nucleocapsid Occurrence ORF pathogenic coronavirus predicted Protein purified reading Respiratory tract infections Result sequence shown structural protein subsequent Topology translation viral particle virion [DOI] 10.1186/1743-422X-7-6 PMC 바로가기 [Article Type] Research
Roles of TNF -α gene polymorphisms in the occurrence and progress of SARS-Cov infection: A case-control studyResearch Article Published on 2008-02-292022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, [키워드] 95% CI acute respiratory syndrome adjusted Analysis association carried case-control study collected data compared conducted cured determine discharged fibrosis found Genetic polymorphism Genotype glucocorticoid Health care worker healthy controls Host genetic factor Infection interstitial locus Logistic lung Lung fibrosis manifested Necrosis not affect Occurrence PCR polymorphism prognosis of patient promoter region protective effect relationship Result risk risk factor role SARS patient SARS patients SARS-CoV infection Sequencing SNP susceptibility TNF TNF-α was used [DOI] 10.1186/1471-2334-8-27 PMC 바로가기 [Article Type] Research Article
Molecular mechanisms of severe acute respiratory syndrome (SARS)Review Published on 2005-01-202022-10-28 Journal: Respiratory Research [Category] Coronavirus, [키워드] acute respiratory syndrome approach caused contribute coronavirus Deleterious Effect effort Epidemics Features Genome Health immune immune system indirect effect infections Infectious disease Interaction Laboratory mechanism molecular mechanisms morbidity and mortality mutability Novel coronavirus Occurrence offer Open reading frame outbreak Pathogenesis Prevent pulmonary pathological Region required Research Respiratory disease SARS SARS-CoV severe Severe acute respiratory syndrome target cell the disease therapy vaccination Vaccine viral genome virulence virus widespread [DOI] 10.1186/1465-9921-6-8 PMC 바로가기 [Article Type] Review