No MERS-CoV but positive influenza viruses in returning Hajj pilgrims, China, 2013–2015Research Article Published on 2017-11-102022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, MERS, [키워드] China Chinese contribute coronavirus detection rate Hajj pilgrims Health indicated influenza A virus influenza B influenza virus Influenza virus International Mecca MERS-CoV MERS-CoV infection Middle East Middle East respiratory syndrome coronavirus (MERS-CoV) molecular Muslim not significantly different participated positive respiratory respiratory syncytial virus respiratory virus respiratory virus respiratory viruses significant difference Spread Symptom tested virus [DOI] 10.1186/s12879-017-2791-0 PMC 바로가기 [Article Type] Research Article
Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after InfectionArticle Published on 2017-08-222022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] administration alterations Altered analysis Cardiovascular disorders clinical Clinical treatment Diseases Effect examination finding Glucose Health healthy controls High-dose indicated Infection infections information investigated Lipid lung metabolism metabolome metabolomic Methylprednisolone Pathologies Patient provided pulse questionnaire recovered recruited response SARS patient SARS patients SARS-CoV SARS-like coronavirus serum severe pneumonia significant difference suggested Survivors susceptibility systemic damage the patient treated tumors Year [DOI] 10.1038/s41598-017-09536-z PMC 바로가기 [Article Type] Article
Comparative Genomics of the Sigatoka Disease Complex on Banana Suggests a Link between Parallel Evolutionary Changes in Pseudocercospora fijiensis and Pseudocercospora eumusae and Increased Virulence on the Banana Host바나나에 대한 Sigatoka 질병 복합체의 비교 유전체학은 Pseudocercospora fijiensis와 Pseudocercospora eumusae의 병렬 진화적 변화와 바나나 숙주의 독성 증가 사이의 연관성을 시사합니다Research Article Published on 2016-08-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acquisition adaptation analysis analyzed assimilation banana biological process caused cell walls change changes in Comparative Comparative analysis Comparative genomics complementary complex conserved convergent evolution core gene Degradation disease disease control Diversity Dothideomycetes driven by effective effector proteins effectors Evolution evolutionary relationships facilitate facilitated fungi gene count gene families gene family Genes Genome genome architecture genome sequence genomes genomic genomic change Genomics higher efficiency Host host immune system identify increase in Increased indicated involved LTR management metabolic pathway metabolic pathways metabolism Modification pathogen pathogenic Pathogens plant cell profile proliferation Radiation remained sequenced Seven significant difference significant differences speciation Still supported understanding utilization virulence virulent [DOI] 10.1371/journal.pgen.1005904 PMC 바로가기 [Article Type] Research Article
RNA sequencing-based analysis of the spleen transcriptome following infectious bronchitis virus infection of chickens selected for different mannose-binding lectin serum concentrationsResearch Article Published on 2016-01-272022-10-28 Journal: BMC Genomics [Category] Coronavirus, MERS, [키워드] Activation adaptive Adaptive immune response Analysis bronchitis caused chicken Concentration contagious coronavirus DE gene Differential gene expression differentially expressed disease euthanized expression expression profile Gene ontology Genes GO term IBV IBV infection immune immune response Immunity Immunoglobulin improvement Infection Infectious bronchitis Infectious Bronchitis Virus Interaction involved leukocyte mannose-binding lectin molecular mechanism post infection Process proliferation Recombination Regulation Result RNA RNA sequencing selected serum significant difference spleen subset supplementary material System T cell T cell activation Transcriptome understanding uninfected was performed were infected were used [DOI] 10.1186/s12864-016-2403-1 PMC 바로가기 [Article Type] Research Article
Changes in the Swine Gut Microbiota in Response to Porcine Epidemic Diarrhea InfectionShort Communication Published on 2015-09-252022-10-31 Journal: Microbes and Environments [Category] Coronavirus, [키워드] 16S rRNA gene affected Bacterial cells change commensal bacteria complex Critical ecosystem epidemic diarrhea Faecalibacterium gastrointestinal tract group Gut gut microbiota Health Host identify Infection large intestine mammal microbiota MOST Next-generation sequencing PEDV Porcine epidemic diarrhea Prevotella response significant difference the healthy virus [DOI] 10.1264/jsme2.ME15046 PMC 바로가기 [Article Type] Short Communication
Polymorphisms in the feline TNFA and CD209 genes are associated with the outcome of feline coronavirus infectionResearch Published on 2014-12-162022-10-28 Journal: Veterinary Research [Category] Coronavirus, MERS, [키워드] A allele allele Alpha association Birman caused CD209 coronavirus Coronavirus infection DC-SIGN Denmark disease domain ECD effective therapy Extracellular facilitate Feline infectious peritonitis FIVE genetic trait Genetic variant Genotype groups Host host gene immune-mediated disease Infection intron lethal disease multifactorial Necrosis Occurrence outcome populations promoter reduce significant difference Single nucleotide polymorphism SNP SNPs statistical suggested supplementary material susceptibility TNF-α USA variant [DOI] 10.1186/s13567-014-0123-6 PMC 바로가기 [Article Type] Research
Detecting Differential Transmissibilities That Affect the Size of Self-Limited OutbreaksResearch Article Published on 2014-10-302022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] Affect amplify Analysis applied approach branching process can be used Canada changes in Clusters Contact contact tracing procedures Coverage cross-protective declined decrease detect disease distribution effective Effectiveness epidemiological Europe evaluate Evidence example facilitate Factor heterogeneity Human human-to-human transmission humans identify indicate individuals Infection infection source Infectious disease MERS-CoV MERS-CoV transmission Middle East National North America occur provide public health quantitative assessment Reproduction number respiratory respiratory syndrome coronavirus respond risk secondary cases significant difference statistical statistically significant Surveillance the timing the United State Transmissibility Transmission transmitted vaccination Variation variety [DOI] 10.1371/journal.ppat.1004452 PMC 바로가기 [Article Type] Research Article
Different Mechanisms of Inflammation Induced in Virus and Autoimmune-Mediated Models of Multiple Sclerosis in C57BL6 MiceResearch Article Published on 2013-08-282022-10-27 Journal: BioMed Research International [Category] Coronavirus, [키워드] accumulated Acute inflammation Autoimmune CD4 CD8 Central nervous system chronic disease CNS Course demonstrated Demyelination disease distribution glycoprotein Immunosuppression induce induced Inflammation Inflammatory Injury involved mechanism MHV MHV-A59 mice microglia Model MOG Multiple pathology patients promote responsible sclerosis significant difference T cell T cells the disease viral toxicity viral-induced [DOI] 10.1155/2013/589048 PMC 바로가기 [Article Type] Research Article
Comparative Pathogenesis of Three Human and Zoonotic SARS-CoV Strains in Cynomolgus MacaquesResearch Article Published on 2011-04-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, Fulltext, 조류인플루엔자, [키워드] acute respiratory syndrome against SARS-CoV change characterized Comparative compared Critical disease cynomolgus macaque Disease model Efficacy Epidemic exacerbated function Gene Heterologous histopathological Host host gene host response Human infect Infected Infection interferon signaling isolates macaque majority Mild pathogen pathogenicity pathway Pathways Prevent radiological regulated Replication SARS-CoV significant difference strain Strains subsequent therapeutic strategy Transmission Vaccine while zoonotic [DOI] 10.1371/journal.pone.0018558 PMC 바로가기 [Article Type] Research Article