Interaction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2Animal Published on 2008-11-012022-10-30 Journal: The Journal of General Virology [Category] Coronavirus, [키워드] ACE-2 Angiotensin converting enzyme-2 assays binding Cell consequence Contact coronavirus coronavirus spike protein different enzyme explain groups host cell Infection Interaction investigated mild respiratory NL63 Protein receptor required residue S protein SARS-CoV SARS-CoV S protein Severe respiratory distress virus [DOI] 10.1099/vir.0.2008/003962-0 PMC 바로가기 [Article Type] Animal
Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell DeterminantResearch Article Published on 2008-10-242022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] alteration amino acid substitution Analysis antigen-specific T cell association Author CD8+ T cell changes in clinical disease complex Complex molecule conformation Consensus Critical CTL cytotoxic determinant Disease progression Diseases elicit Enhancing epitope escape expressed functional Hepatitis histocompatibility HIV immune response immune responses immunodominant Infected Local Major memory MHC class I mice molecular basis motif mouse hepatitis mutated Mutation natural infection occur pathogen peptide performed prevention PROTECT Protective recombinant residue response significantly higher stability Subdominant T cell T cell epitope T cell response tumor immunity Vaccine development viral infection virus wildtype [DOI] 10.1371/journal.ppat.1000186 PMC 바로가기 [Article Type] Research Article
Antiviral therapy for respiratory tract infectionsarticle Published on 2008-09-262024-09-02 Journal: Respirology (Carlton, Vic.) [Category] 대상포진, [키워드] Antiviral nosocomial respiratory tract infection virus [DOI] 10.1111/j.1440-1843.2008.01404.x PMC 바로가기 [Article Type] article
Importance of cholesterol for infection of cells by transmissible gastroenteritis virusArticle Published on 2008-09-162022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] addressed Cell cellular cellular membrane cellular membranes cholesterol compared coronavirus depleting Efficiency enveloped virus expected found gastroenteritis Importance Infection Infectivity involved Lipid rafts membrane plasma membrane Protein question raise reduced significantly TGEV viral envelope virus [DOI] 10.1016/j.virusres.2008.07.023 PMC 바로가기 [Article Type] Article
SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic ReticulumResearch Article Published on 2008-09-162022-10-28 Journal: PLoS Biology [Category] Coronavirus, [키워드] acute respiratory syndrome alteration Analysis Antiviral applied arising Author biochemical characterized complex connection coronavirus cytoplasm cytosol Defense defined dissect double-stranded RNA driven by early stage electron tomography Endoplasmic reticulum endoplasmic reticulum membrane enzyme ER membrane host cell host cell membrane host cell membranes host cells human pathogen implicated in viral induce Infected infected cell interior invagination mechanism mechanisms membrane membrane-bound membranes Microscopy network question raise replicate Replication replication complex replicative protein reported Reticulum reveal RNA RNA genome RNA synthesis RNA virus RNA viruses SARS-coronavirus SARS-CoV Structure subunits Support thought tomography ultrastructure unique Vesicle vesicles viral replication viral RNA synthesis virus Virus-host interactions Web [DOI] 10.1371/journal.pbio.0060226 PMC 바로가기 [Article Type] Research Article
Upper respiratory virus detection without parent-reported illness in children is virus-specificArticle Published on 2008-06-052022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, [키워드] 229E Adenovirus children Complication coronavirus detected determine different Follow-up Frequency illness independent Infection influenza A Influenza virus less nasal objective OC43 parainfluenza parental PCR PCR assay Prospective relative frequency respiratory syncytial virus respiratory virus Result rhinovirus RSV secretion subject upper upper respiratory upper respiratory tract virus virus detection viruses [DOI] 10.1016/j.jcv.2008.04.008 PMC 바로가기 [Article Type] Article
Detection and Prevalence Patterns of Group I Coronaviruses in Bats, Northern GermanyResearch Published on 2008-04-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] age amplification association bat bat coronavirus bats Chinese clade colonies coronavirus correlated detection different found Germany gravidity group lactation Lineage Myotis pattern Pipistrellus population level Prevalence Research SARS Sex significantly tested Transmission type I virus [DOI] 10.3201/eid1404.071439 PMC 바로가기 [Article Type] Research
Role of human metapneumovirus, human coronavirus NL63 and human bocavirus in infants and young children with acute wheezingResearch Article Published on 2008-03-212022-11-01 Journal: Journal of medical virology [Category] Coronavirus, Fulltext, MERS, [키워드] Adenovirus African Analysis children collected coronavirus Culture found Gene Genotype hospital Inc Infant influenza A less lineages median age métapneumovirus nasal swab NL63 novel respiratory viruses occurred Other respiratory viruses parainfluenza PCR pediatric positive presenting Prevalence Prospective Study Respiratory pathogens respiratory virus respiratory viruses role RSV RT‐PCR sequenced shell South virus viruses was performed wheezing [DOI] 10.1002/jmv.21135 PMC 바로가기 [Article Type] Research Article
Confronting Potential Influenza A (H5N1) Pandemic with Better VaccinesPerspective Published on 2007-10-012023-05-31 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] antibody broad-spectrum immunity CTL response Cytokines influenza (H5N1) pandemic Perspective therapeutic vaccines Vaccine virus [DOI] 10.3201/eid1310.061262 PMC 바로가기 [Article Type] Perspective
Evolutionary Relationships between Bat Coronaviruses and Their HostsResearch Published on 2007-10-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome Analysis association bat bats biologic caused coronavirus Coronaviruses CoV CoVs Evolution evolutionary relationship examined Host host shifts Human implication occurred outbreak Phylogeny phylogeography recent related related viruses relationship Research Respiratory illness RNA-dependent RNA polymerase SARS SARS-CoV sequence shifting suggested trait traits virus [DOI] 10.3201/eid1310.070448 PMC 바로가기 [Article Type] Research