Gramicidin S and melittin: potential anti-viral therapeutic peptides to treat SARS-CoV-2 infectionGramicidin S 및 Melittin : SARS-COV-2 감염을 치료하는 잠재적 항 바이러스 치료 펩티드Article Published on 2022-03-022022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 신약개발, 유전자 메커니즘, 치료제, [키워드] Analysis Anti-SARS-CoV-2 Activity Anti-viral Antibacterial Antiviral approach Bacillus brevis candidate Cell Biology COVID19 cytotoxicity de novo decrease drug Drug discovery GRAMICIDIN in vitro indicated Infection less melittin molecules mRNA pandemic peptide peptides post infection Protein regulated SARS-CoV-2 SARS-COV-2 infection Significant significant decrease the disease the SARS-CoV-2 therapeutic treat treated Treatment Vero Cell Vero cells Viral viral clearance viral infections Viral load [DOI] 10.1038/s41598-022-07341-x PMC 바로가기 [Article Type] Article
The vital role of animal, marine, and microbial natural products against COVID-19Covid-19에 대한 동물, 해양 및 미생물 천연 제품의 중요한 역할Review Published on 2022-03-022022-09-10 Journal: Pharmaceutical Biology [Category] 신약개발, 치료제, [키워드] 3CLpro animal Anti-inflammatory Antiviral approach Bromelain carrageenan clinical trial clinical trials Combination combination treatment Context COVID-19 COVID-19 therapy COVID19 database derivative Direct Drug development Effect Efficacy evaluated flavonoids hACE2 highlighting host proteins immunomodulatory properties in silico inhibitory less management mechanism microbial microbial products microorganisms MOST nasal Nasal spray NF-κB objective omega-3 omega-3 supplementation organism outbreak pandemic Pathogenesis peptide peptides pharmacological plants PLPro Prevent profile quercetin raw data researcher Result SARS-CoV-2 SARS-CoV-2coronavirus Science Science Direct searched synergistic synergistic effects tannins target tested therapy these compound these compounds Treatment Viral viral entry Vitamin C Zinc [DOI] 10.1080/13880209.2022.2039215 PMC 바로가기 [Article Type] Review
Detailed epitope mapping of SARS-CoV-2 nucleoprotein reveals specific immunoresponse in cats and dogs housed with COVID-19 patientsSARS-CoV-2 핵단백질의 상세한 에피토프 매핑은 COVID-19 환자와 함께 수용된 고양이와 개에서 특정 면역 반응을 나타냅니다Article Published on 2022-03-012022-09-11 Journal: Research in veterinary science [Category] MERS, SARS, 진단, 치료법, [키워드] animals Antigen antigenic C-terminus coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID19 develop disease disease control domain Double antigen ELISA ELISA epitope epitope mapping gold gold standard Human immunized Infection initial neutralization test pandemic Patient plaque PRNT Protein raising reported representing respiratory respiratory syndrome coronavirus 2 reveal SARS-CoV-2 SARS-CoV-2 nucleoprotein sera Serological assay specificity susceptible target Transmission Viral Viral antigen was used with COVID-19 [DOI] 10.1016/j.rvsc.2021.12.020 PMC 바로가기 [Article Type] Article
An analysis of antibody responses and clinical sequalae of the Sinopharm HB02 COVID19 vaccine in dialysis patients in the United Arab Emirates아랍에미리트의 투석 환자에서 Sinopharm HB02 COVID19 백신의 항체 반응 및 임상 후유증 분석Article Published on 2022-03-012022-09-11 Journal: Nephrology (Carlton, Vic.) [Category] SARS, 변종, [키워드] adverse events Analysis anti-spike antibodies anti-spike antibody antibodies antibody Antibody Response Antibody responses appear baseline booster dose Case fatality rate Clinical effect Cohort Course COVID COVID-19 COVID-19 vaccination COVID19 dialysis dose examined Fatality rate General population Haemodialysis haemodialysis patients humoral immune response humoral immune responses Humoral response humoral responses immune responses individuals Infection occur Patient patients positive PROTECT reduction in response Side-effects Sinopharm Standard survival the antibody response the vaccine to define United Arab Emirate vaccination vaccination schedule Vaccine were given [DOI] 10.1111/nep.13980 PMC 바로가기 [Article Type] Article
Humoral and cellular immune responses to SARS CoV-2 vaccination in People with Multiple Sclerosis and NMOSD patients receiving immunomodulatory treatments면역 조절 치료를 받는 다발성 경화증 환자 및 NMOSD 환자에서 SARS CoV-2 예방 접종에 대한 체액 및 세포 면역 반응Observational Study Published on 2022-03-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] MERS, 임상, 진단, [키워드] Acetate B-cell B-cell response cellular Cellular immune response cellular immune responses Cladribine clinician Course COVID COVID 19 COVID19 depleting Dimethylfumarate disease humoral humoral immune response immune immunomodulatory immunomodulatory medications impair inhibitor Multiple Multiple Sclerosis therapy Natalizumab Neuromyelitis Optica not affect pandemic Patient quantified receiving reduced SARS CoV-2 SARS CoV2 sclerosis Support T cell responses T-cell responses Therapies therapy Treatment vaccination vaccination efficacy Viral antigen [DOI] 10.1016/j.msard.2022.103554 PMC 바로가기 [Article Type] Observational Study
Experience With the Use of Baricitinib and Tocilizumab Monotherapy or Combined, in Patients With Interstitial Pneumonia Secondary to Coronavirus COVID19: A Real-World Study코로나바이러스 COVID19에 따른 간질성 폐렴 환자에서 바리시티닙과 토실리주맙 단독 요법 또는 병용 요법의 사용 경험: 실제 연구Article Published on 2022-03-012022-09-12 Journal: Reumatología clinica [Category] MERS, SARS, 진단, [키워드] Admission age average Baricitinib Combined COVID-19 COVID19 died discharge English experience group ICU interstitial pneumonia males media medical record monotherapy Neumonía intersticial PaO paO2/fiO2 Patient patients patients died Quince required secondary to Side effect Side effects Spanish Symptoms TCZ Tocilizumab treated Treatment UCI. [DOI] 10.1016/j.reumae.2020.10.006 PMC 바로가기 [Article Type] Article
Efficacy of Favipiravir in treatment of mild & moderate COVID-19 infection in Nepal: a multi-center, randomized, open-labelled, phase III clinical trialConference abstract Published on 2022-03-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 임상, [키워드] adverse events Analysis Clinical improvement clinical trial comparable COVID-19 patient COVID19 Data analysis elevated eligibility criteria enrolled Favipiravir hospital Infection Liver function material Mild mild infection moderate Moderate COVID-19 Nepal onset of symptoms outcome participant Patient Placebo Preliminary data preliminary report Randomized Randomly receiving Remdesivir reported Result RT-PCR Side effect the patient the study group Tolerability Treatment uric acid while [DOI] 10.1016/j.ijid.2021.12.109 [Article Type] Conference abstract
Herpes zoster (shingles) complicating the course of COVID19 infectionCOVID-19 감염의 경과를 복잡하게 하는 대상포진Case Reports Published on 2022-03-012023-05-31 Journal: The Journal of dermatological treatment [Category] 대상포진, 두창, 수두, 홍역, [키워드] COVID19 infections Varicella-zoster virus (VZV) [DOI] 10.1080/09546634.2020.1782823 [Article Type] Case Reports
Auditory evaluation of infants born to COVID19 positive mothersArticle Published on 2022-03-012023-07-08 Journal: American journal of otolaryngology [Category] COVID19(2023년), [키워드] COVID19 hearing loss Newborn hearing screening SARS-CoV-2 vertical transmission [DOI] 10.1016/j.amjoto.2022.103379 PMC 바로가기
Herpes zoster (shingles) complicating the course of COVID19 infectionCase Reports Published on 2022-03-012023-05-31 Journal: The Journal of dermatological treatment [Category] 두창, 수두, 홍역, [키워드] COVID19 infections Varicella-zoster virus (VZV) [DOI] 10.1080/09546634.2020.1782823 [Article Type] Case Reports