High prevalence of SARS-CoV-2 infection among food delivery riders. A case study from Quito, Ecuador음식 배달 라이더 사이에서 SARS-CoV-2 감염의 높은 유병률. 에콰도르 키토의 사례 연구Article Published on 2021-05-202022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] 2019-nCoV age Americas average average age BSL2 calculated CDC center city consumer Contagion Control COVID-19 COVID-19 pandemic delivery diagnostic disease control Ecuador exposure to females food Food delivery health system health systems identify incidence rate Laboratory less lockdown majority male men Mild symptom mild symptoms Molecular biology nasopharyngeal swabs National Novel coronavirus offer online delivery p value pandemic Panel Population positive Prevalence processed Quito reduce reported restaurant Riders risk RT-PCR testing RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection statistically significant subject tested Viral load was used [DOI] 10.1016/j.scitotenv.2021.145225 PMC 바로가기 [Article Type] Article
Loss of Furin Cleavage Site Attenuates SARS-CoV-2 PathogenesisArticle Published on 2021-05-202023-06-18 Journal: Nature [Category] Fulltext, SARS, [키워드] 2019-nCoV coronavirus COVID-19 furin-cleavage SARS-CoV-2 spike [DOI] 10.1038/s41586-021-03237-4 PMC 바로가기 [Article Type] Article
Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methodsSARS-CoV-2 간접 및 직접 RT-qPCR 검출 방법 비교Comparative Study Published on 2021-05-172022-09-01 Journal: Virology Journal [Category] SARS, 진단, 치료기술, [키워드] 2019-nCoV Analysis approach best BGI boiling caused Clinical diagnosis comparable Cost analysis COVID-19 COVID-19 pandemic Critical Ct values Detection limit detection system diagnostic diagnostics Direct detection evaluated exhibited extracted RNA gold gold standard handling initial Invitrogen isolation procedures less lysis buffer methodology MOST NEB other treatment Patient performed Primers provided purified viral RNA Qiagen reagents reduced Result RNA extraction RNA extraction kit RNA isolation RNase RNase inhibitor RT-qPCR SARS-CoV-2 SARS-CoV-2 virus sensitive sensitivity specificity supplementary material SYBR Green TaqMan tested the SARS-CoV-2 virus Universal Viral viral genome Viral RNA virus [DOI] 10.1186/s12985-021-01574-4 PMC 바로가기 [Article Type] Comparative Study
Systematic review and meta-analysis of tocilizumab in persons with coronavirus disease-2019 (COVID-19)코로나바이러스 감염증-2019(COVID-19) 환자에 대한 토실리주맙의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-05-172022-09-12 Journal: Leukemia [Category] MERS, SARS, 임상, 진단, [키워드] 2019-nCoV 95% confidence interval Analysis Boolean operator Boolean operators Cohort Cohort studies cohort study Control coronavirus coronavirus disease coronavirus disease-2019 COVID-19 death determine discharged Efficacy Endpoint Hospitalization ICU admission Immunotherapy Infectious diseases Invasive mechanical ventilation Jadad scale Meta-analysis not decreased performed question Randomized randomized trial reduced risk relative Relative risk review risk of death SARS-CoV-2 searched Secondary infection secondary infections subject Tocilizumab was used Web of Science with COVID-19 [DOI] 10.1038/s41375-021-01264-8 PMC 바로가기 [Article Type] Meta-Analysis
Neonatal SARS-CoV-2 Infection: Practical TipsReview Published on 2021-05-172022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] 2019-nCoV acute respiratory distress age beta-coronavirus Breastfeeding cause children China clinical care Clinical course Clinical management COVID-19 COVID-19 infection death Evidence group groups humans Infant Infants infect Infection International management Mild mother Neonatal Neonate Neonates Newborn pandemic Pathogenesis Pneumonia Pregnancy pregnant women provide recommendation risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 SARS-CoV2 infection severe pneumonia susceptible Symptom syndrome Transmission upper respiratory tract virus women Wuhan [DOI] 10.3390/pathogens10050611 PMC 바로가기 [Article Type] Review
SARS-CoV-2 in animals: potential for unknown reservoir hosts and public health implications동물의 SARS-CoV-2: 알려지지 않은 저수지 숙주의 가능성 및 공중 보건 영향Review Published on 2021-05-142022-09-10 Journal: The Veterinary Quarterly [Category] SARS, 변종, [키워드] 2019-nCoV acute respiratory syndrome acute respiratory syndrome coronavirus animal animals bats cats China Contact coronavirus COVID-19 cynomolgus macaques determine Evidence evidence of facilitated ferret ferrets globe hamster Host host range Human human-to-human transmission implication initial instances mammalian mink natural infection populations public health raccoon dogs reported reservoirs respiratory Result rhesus macaques SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission SARS-CoV-2 variant severe acute respiratory syndrome coronavirus 2 susceptibility susceptible Transmission transmission of SARS-CoV-2 transmitted Viral white-tailed deer wild animal wildlife reservoir zoos [DOI] 10.1080/01652176.2021.1921311 PMC 바로가기 [Article Type] Review
Tools and Techniques for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/COVID-19 DetectionReview Published on 2021-05-122023-06-14 Journal: Clinical microbiology reviews [Category] MERS, SARS, [키워드] 2019-nCoV Antigen Biomarkers coronavirus COVID-19 NAAT Next-generation sequencing PCR SARS-CoV-2 serology [DOI] 10.1128/CMR.00228-20 PMC 바로가기 [Article Type] Review
Ophthalmology Consultation Plan in the Context of 2019-nCoVMedicine Published on 2021-05-122022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 2019-nCoV consultation Context guidelines ophthalmology plan SARS-CoV-2 Transmission [DOI] 10.3389/fmed.2021.618599 PMC 바로가기 [Article Type] Medicine
Clinical diagnostic performance evaluation of five immunoassays for antibodies to SARS-CoV-2 diagnosis in a real-life routine care setting실생활 일상 진료 환경에서 SARS-CoV-2 진단에 대한 항체에 대한 5가지 면역분석법의 임상 진단 성능 평가Comparative Study Published on 2021-05-032022-09-01 Journal: The Pan African Medical Journal [Category] SARS, 진단, [키워드] 2019-nCoV Accuracy acute SARS-CoV-2 infection Admission age analyzed antibody automated clinical clinical samples coefficient complementary coronavirus COVID-19 Diagnosis diagnosis of COVID-19 diagnosis of SARS-CoV-2 diagnostic diagnostics evaluated FIVE gold gold standard Health care Health care worker health care workers IgM antibody IgM test IgM/IgG immunoassay IQR Kappa coefficient lateral flow majority male median molecular nCoV Negative PCR Nigeria no symptom no symptoms on admission onset of symptoms option pathogen Patient positive positive PCR rapid diagnostic kits rapid response Rapid test receiving resource routine care RT-PCR SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-COV-2 infection sensitivity serological test Serological tests serology specificity specimen state Symptom test cassette tested Treatment unique while [DOI] 10.11604/pamj.2021.39.3.26471 PMC 바로가기 [Article Type] Comparative Study
In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)인-실리코 상동성은 2019-nCoV N-단백질(N 말단 도메인)에 대한 RNA 결합 억제제의 식별을 지원합니다.Article Published on 2021-05-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] SARS, 치료법, [키워드] 2019 novel corona virus 2019-nCoV approved bind binding binding free energy complex Compound compounds coronavirus CoV docking score drug design drug-likeness free energy homology identify in vitro inhibitor inhibitors molecular molecular dynamics N protein N proteins N Terminal N terminal domain N-protein nCoV novel corona virus NTD nucleocapsid protein pharmacokinetic Protein pyrimidone RNA RNA binding SARS-CoV-2 screened selected Structure target targets the N protein theophylline Virtual screening virus replication [DOI] 10.1080/07391102.2020.1753580 PMC 바로가기 [Article Type] Article