SARS-CoV-2 rapid antigen tests provide benefits for epidemic control – observations from Austrian schoolsSARS-CoV-2 급속 항원 검사는 전염병 통제에 이점을 제공합니다 - 오스트리아 학교의 관찰Article Published on 2022-05-012022-09-11 Journal: Journal of clinical epidemiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Antigen antigen tests benefit Breakthrough infection breakthrough infections children Cohort conducted COVID-19 COVID-19 pandemic Delta detect detectable diagnose diagnostic diagnostic test effective Efficacy Epidemic Evidence false-positive rate information Large-scale testing Lateral Lateral flow device Live virus logistics observation PCR test PCR tests powerful tool Protein Public public health Rapid rapid antigen test Rapid antigen tests Repeat Repeat testing Reproduction number respiratory tract SARS-CoV-2 School Schools spring suppress tested the disease viral genomes Viral load viral loads virus genome virus particles while [DOI] 10.1016/j.jclinepi.2022.01.002 PMC 바로가기 [Article Type] Article
Immunogenicity of BNT162b2 vaccine against the Alpha and Delta variants in immunocompromised patients with systemic inflammatory diseases전신 염증성 질환이 있는 면역 저하 환자에서 알파 및 델타 변이체에 대한 BNT162b2 백신의 면역원성Article Published on 2022-05-012022-09-11 Journal: Annals of the rheumatic diseases [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] abrogated Alpha alpha and delta variants analysed anti-spike antibodies anti-spike antibody anti-Spike IgG B-cell B.1.617.2 BNT162b2 BNT162b2 vaccine Breakthrough infection breakthrough infections Control controls COVID-19 Delta delta variant Delta variants dose effort Endpoint evaluate exhibiting healthcare humoral Humoral response Immune escape immunocompromised individual immunocompromised individuals Immunocompromised patient Immunocompromised patients immunogenicity impairing IMPROVE individual infected with SARS-CoV-2 Inflammatory diseases Kinetics methotrexate mounted neutralisation neutralising Neutralising activity of BNT162b2 Other Patient primary endpoints Prospective raise regimen responses rituximab SARS-CoV-2 secondary Secondary endpoints sera Seroconversion Specific T-cell response strain Strains Support systemic inflammatory disease systemic inflammatory diseases T-cell T-cell Response T-cell responses therapeutic treated vaccination Vaccine Viral viral fitness [DOI] 10.1136/annrheumdis-2021-221508 PMC 바로가기 [Article Type] Article
Immune evasion and chronological decrease in titer of neutralizing antibody against SARS-CoV-2 and its variants of concerns in COVID-19 patientsSARS-CoV-2 및 COVID-19 환자의 우려 변종에 대한 면역 회피 및 중화 항체 역가의 시간적 감소Article Published on 2022-05-012022-09-11 Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acquisition Alpha Beta Breakthrough infection breakthrough infections Chronological change concerning Course COVID-19 COVID-19 patient COVID-19 patients D614G decrease Delta delta variant disease severity ELISA enrolled examined Gamma Immune evasions Infection Neutralizing antibodies neutralizing antibody Neutralizing titer neutralizing titers prevalent strain problem SARS-CoV-2 strain Strains thought titers vaccination variant variants of concern variants of SARS-CoV-2 Variants strain. Wuhan Wuhan-Hu-1 [DOI] 10.1016/j.clim.2022.108999 PMC 바로가기 [Article Type] Article
Glycaemic control is associated with SARS-CoV-2 breakthrough infections in vaccinated patients with type 2 diabetesObservational Study Published on 2022-04-282022-10-05 Journal: Nature Communications [Category] COVID19(2023년), SARS, 임상, 치료법, [키워드] 95% CI 95% confidence interval adjusted hazard ratio affected Beta Breakthrough infection breakthrough infections Campania CD4 characterized COVID-19 vaccine Cox regression Factors Follow-up glycaemic control healthcare immune response immune responses incidence increased risk influence Italy Patient prospective observational study receiving SARS-CoV-2 Sex significantly smoking subject T2D type 2 diabete vaccination Vaccine virus-neutralizing antibody [DOI] 10.1038/s41467-022-30068-2 PMC 바로가기 [Article Type] Observational Study
Long-Lasting T Cell Responses in BNT162b2 COVID-19 mRNA Vaccinees and COVID-19 Convalescent PatientsBNT162b2 COVID-19 mRNA 백신 및 COVID-19 회복기 환자에서 장기간 지속되는 T 세포 반응Article Published on 2022-04-222022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha antibody antibody levels Beta BNT162b2 Breakthrough infection breakthrough infections Cell mediated immunity coronavirus COVID-19 COVID-19 disease COVID-19 patients cytokine cytokine production delta variant Delta variants Gamma Health care Health care worker health care workers humoral Humoral immunity Infection marker mononuclear cell mononuclear cells more difficult mRNA neutralize Peripheral blood Peripheral blood mononuclear cells persistence Prevent PROTECT question raise report respiratory response SARS-CoV-2 severe acute respiratory syndrome Coronavirus T cell T cell mediated immunity T cell response T cell responses Th1 vaccination Vaccine Vaccines variant variants virus [DOI] 10.3389/fimmu.2022.869990 PMC 바로가기 [Article Type] Article
Characterization of immune responses in fully vaccinated individuals after breakthrough infection with the SARS-CoV-2 delta variantSARS-CoV-2 델타 변이체에 의한 돌발성 감염 후 백신을 완전히 접종한 개인의 면역 반응 특성화Article Published on 2022-04-202022-09-11 Journal: Science Translational Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anamnestic antibody Antibody Response Antibody titers binding antibody Breakthrough infection breakthrough infections CD8 characterization Cluster Combination coronavirus demonstrated immune response individual Infection Massachusett Massachusetts mucosal nasal Neutralizing antibody titer neutralizing antibody titers Peripheral blood population immunity positive reported respiratory robust SARS-CoV-2 secretion serum antibody serum antibody response severe acute respiratory syndrome Coronavirus Spike protein T cell T cell response T cell responses tested the SARS-CoV-2 These data vaccinated individual vaccinated individuals vaccination variant variants waning immunity widespread [DOI] 10.1126/scitranslmed.abn6150 PMC 바로가기 [Article Type] Article
Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?SARS CoV-2 오미크론 변종은 델타 변종보다 더 치명적이고 전염성이 있습니까?Review Published on 2022-04-112022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus affected Brazil breakthrough infections catastrophic caused changed Characteristics Community Consequences contagious coronavirus country COVID-19 death Delta delta variant dominant fatality FIVE France genetic variants greater increased mortality India Infection information meta-data omicron Omicron variant Omicron variants other variants outbreak pandemic Preliminary data reported SARS CoV-2 SARS-CoV-2 SARS-CoV-2 variant selected severe acute respiratory syndrome Coronavirus severity severity and mortality South Africa The United States Transmissibility United Kingdom United States vaccination variant variants variants of concern [DOI] 10.3390/ijerph19084586 PMC 바로가기 [Article Type] Review
In-depth analysis of SARS-CoV-2-specific T cells reveals diverse differentiation hierarchies in vaccinated individualsSARS-CoV-2-특이적 T 세포에 대한 심층 분석은 백신 접종을 받은 개인의 다양한 분화 계층을 보여줍니다Article Published on 2022-04-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Adaptive immune response Adaptive immunity Analysis approach breadth Breakthrough infection breakthrough infections CD4+ T cell CD4+ T cells clinical trial clinical trials COVID-19 COVID-19 pandemic cytokine profile determinant effective Efficacy feature fraction Fractions identify IL-2 immune immunology indicate individual induce investigated Last Longevity magnitude majority mutant produced reactive recall Region responders reveal S-protein SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2-specific T cell SARS-CoV-2-specific T cells T cell T cell response T cells TNF-α vaccinated individual vaccinated individuals vaccination Vaccine variants of concern [DOI] 10.1172/jci.insight.156559 PMC 바로가기 [Article Type] Article
Antibody responses induced by the BNT162b2 mRNA COVID-19 vaccine in healthcare workers in a single community hospital in Japan일본 단일 커뮤니티 병원 의료 종사자의 BNT162b2 mRNA COVID-19 백신에 의해 유도된 항체 반응Article Published on 2022-04-012022-09-12 Journal: Journal of infection and chemotherapy : official j [Category] 진단, [키워드] acquisition age antibody Antibody Response Antibody titer Antibody titers benefit BNT162b2 mRNA BNT162b2 vaccine breakthrough infections Characteristics collected Community Complete conducted coronavirus disease COVID-19 COVID-19 vaccine dose Effectiveness Elecsys® Anti-SARS-CoV-2 S electrochemiluminescence immunoassay enrolled evaluated expected female FIVE General population Hakodate healthcare worker higher risk hospital Infection Japan organization participant Participants Patient persistence positive Protective protective effect reported SARS-CoV-2 second dose serum sample single-center study the median vaccination Vaccine vaccine doses were measured women [DOI] 10.1016/j.jiac.2021.12.015 PMC 바로가기 [Article Type] Article
SARS COV-2 anti-nucleocapsid and anti-spike antibodies in an emergency department healthcare worker cohort: September 2020 – April 2021응급실 의료 종사자 집단의 SARS COV-2 항뉴클레오캡시드 및 항스파이크 항체: 2020년 9월 - 2021년 4월Article Published on 2022-04-012022-09-11 Journal: The American journal of emergency medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] 95% CI age anti-spike antibodies anti-spike antibody antibody antibody level antibody levels Antibody Response Antigen baseline BNT162b2 Breakthrough infection breakthrough infections conducted Course COVID-19 infection decrease described emergency department examined Factor Healthcare system healthcare worker IgG antibodies IgG antibody immunogenicity incidence Infection mRNA mRNA-1273 nucleocapsid nucleocapsid antigen participant positive predictor prospective cohort study reduced SARS-CoV-2 SARS-CoV-2 antibodies SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 spike antigen seronegative participant strained tested the antibody response the SARS-CoV-2 threshold vaccination Vaccine Vaccine immunogenicitiy. were measured [DOI] 10.1016/j.ajem.2022.01.055 PMC 바로가기 [Article Type] Article