A Comparative Study of the Plasma Chemokine Profile in COVID-19 Patients Infected with Different SARS-CoV-2 Variants다양한 SARS-CoV-2 변이체에 감염된 COVID-19 환자의 혈장 케모카인 프로필 비교 연구Comparative Study Published on 2022-08-132022-09-11 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 유전자 메커니즘, [키워드] Activation acute respiratory distress acute respiratory distress syndrome Affect blood plasma cause caused CCL11 CCL2 CCL2/MCP-1 CCL22 CCL3 CCL4 CCL7 cellular and molecular Cellular and molecular mechanisms chemoattraction chemokine chemokines Clinical course common cold Comparative Concentration concentrations COVID-19 CX3CL1 CXCL1 CXCL10 CXCL10/IP-10 CXCL8 CXCL9 Delta disease severity drop Eotaxin Genetic variant IL-8 Immune cell immune cells immune responses in viral Inflammation involved Lower respiratory tract Macrophage macrophage-derived chemokine. manifestation MCP-1 MCP-3 mechanism Mutation omicron Patient Pneumonia profile proliferation Protein respiratory distress SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants significantly statistically significant Symptom syndrome upper and lower respiratory tracts variant variants variants of SARS-CoV-2 Viral proteins viral variant virion virus Wuhan strain [DOI] 10.3390/ijms23169058 PMC 바로가기 [Article Type] Comparative Study
A case of ANCA-associated vasculitis in a 16-year-old female following SARS-COV-2 infection and a systematic review of the literatureSARS-COV-2 감염 후 16세 여성에서 발생한 ANCA 관련 혈관염 1예 및 체계적인 문헌 고찰Case Reports Published on 2022-08-132022-09-11 Journal: Pediatric Rheumatology Online Journal [Category] SARS, 바이오마커, 진단, [키워드] Antineutrophil cytoplasmic antibody Asthma Autoimmune disease Autoimmunity cause Child children clinical outcomes Comorbidities cough COVID-19 infection develop diagnosed elevated Evidence female Follow-up Glucocorticoids hearing loss highlight improve clinical outcomes Infection inflammatory markers Laboratory lesions Mild mycophenolate mycophenolate mofetil nodule Patient patients pediatric persistent cough positive Pulmonary function tests Radiographic Rash rituximab SARS-CoV-2 symptomatic improvement Symptoms systematic review treated Treatment Trigger Vasculitis virus wheezing [DOI] 10.1186/s12969-022-00727-1 PMC 바로가기 [Article Type] Case Reports
Association between HLA-C alleles and COVID-19 severity in a pilot study with a Spanish Mediterranean Caucasian cohort스페인 지중해 백인 코호트를 대상으로 한 파일럿 연구에서 HLA-C 대립형질과 COVID-19 심각성 사이의 연관성Article Published on 2022-08-122022-09-11 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, [키워드] age allele analyzed antiviral response association Asymptomatic cause Cell cell surface class Clinical characteristics clinical presentation Clinical presentations Cohort Comorbidity contrary COVID-19 COVID-19 severity Critical described determine disease epitope Epitopes expressed Factor fatal disease Gender groups HLA HLA allele HLA alleles HLA class I HLA-A HLA-B HLA-B allele HLA-B alleles HLA-C HLA-C allele HLA-C alleles HLA-C1 Host hyperinflammatory state immune response individual Infection involved KIR gene male management mechanism Mild mild infection no significant difference no significant differences outcomes pandemic peptide peptides pilot study recruited SARS-CoV-2 protein SARS-CoV-2 proteins significant difference significant differences small sample size Spain Spanish T cells β2-microglobulin [DOI] 10.1371/journal.pone.0272867 PMC 바로가기 [Article Type] Article
COVID-19 Self-Test Data: Challenges and Opportunities – United States, October 31, 2021-June 11, 2022COVID-19 자가 테스트 데이터: 도전과 기회 - 미국, 2021년 10월 31일-2022년 6월 11일Article Published on 2022-08-122022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 치료기술, [키워드] addition agency Care care provider cause CDC challenge clinically Combination Completeness contributed COVID-19 COVID-19 case COVID-19 tests Demographic variables detect Health Health care IMPROVE include Increased indicated infection with SARS-CoV-2 information Infrastructure opportunity performed point-of-care point-of-care test point-of-care tests positive public health public health authorities public health authority receive reduce reported Reporting risk reduction Supply chain Surveillance Treatment United States virus Volume website [DOI] 10.15585/mmwr.mm7132a1 PMC 바로가기 [Article Type] Article
Genomic surveillance of SARS-CoV-2 in Puerto Rico enabled early detection and tracking of variants Research Published on 2022-08-112022-10-05 Journal: Communications Medicine [Category] 변종, 치료기술, [키워드] agency Analysis approach cause circulation competing conducted COVID-19 COVID-19 case COVID-19 pandemic Critical Epidemic event genomic Genomic surveillance Health highlight Lineage Local Molecular epidemiology phylogenetic inference predominant public health Public health responses replaced Result SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomic surveillance SARS-CoV-2 variant sequenced Spread spread to study period Surveillance The United States variant virus [DOI] 10.1038/s43856-022-00168-7 [Article Type] Research
Nanomechanical analysis of SARS-CoV-2 variants and predictions of infectiousness and lethalityArticle Published on 2022-08-102022-11-16 Journal: Soft matter [Category] SARS, 변종, [키워드] Alpha variant Analysis approach B.1.351 B.1.617.2 Beta cause circulation COVID-19 D614G D614G mutation delta variant Effect epidemiological estimate explain higher infectivity interactions less Lineage Lineage B.1.1.7 molecular mutate Mutation offer pathogen pathway predict predicted Predictive Prevalence SARS-CoV-2 variant spike mutation Spike protein Spread strain variant variants virus virus spike protein viruses [DOI] 10.1039/d1sm01181b PMC 바로가기
A fatal SARS-coronavirus-2 induced bone marrow aplasia complicated with invasive fungal infection and severe neutropenic enterocolitis침습성 진균 감염 및 중증 호중구감소성 장염을 동반한 치명적인 SARS-코로나바이러스-2 유도 골수 무형성증Case Reports Published on 2022-08-092022-09-12 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] age Anemia Aplastic anemia Atypical bone Bone marrow Bone marrow-induced aplasia cause children clinical manifestation complications condition consequence coronavirus disease COVID-19 Critical cross-reactivity demonstrated develop diagnosed diagnostic investigation died Disseminated intravascular coagulopathy Fever Fungal infection healthy HIV Inconclusive infected with SARS-CoV-2 invasive lack leukemia mimicking Pancytopenia Patient Prognosis reactive recognize repeated risk SARS-CoV-2 antibody SARS-COV-2 infection Symptom Symptoms vaccination [DOI] 10.1186/s12879-022-07599-6 PMC 바로가기 [Article Type] Case Reports
Identification of differentially expressed genes and their major pathways among the patient with COVID-19, cystic fibrosis, and chronic kidney diseaseResearch article Published on 2022-08-072022-10-05 Journal: Informatics in Medicine Unlocked [Category] 바이오마커, 변종, [키워드] analysed Analysis bioinformatics cause Chronic kidney disease CKD Comorbidity COVID-19 COVID-19 disease cystic fibrosis dataset differentially expressed gene Differentially expressed genes disease disease categories drug expression profiling fibrosis FOXN2 functional Gene regulatory networks help HNF4A identification identify indicated Infectious disease Interaction involved majority MicroRNAs Mild moderate Multiple Ontology pathophysiological pathway Patient patients with COVID-19 performed Potential biomarker predicted protein-protein interaction PRPF31 reducing regulated researcher respiratory symptoms RIOK3 SARS-CoV-2 SARS-CoV-2 virus System biology the patient therapeutic molecules transcription factor Transcriptomic profiling UBC upregulated upregulated genes virus was done with COVID-19 [DOI] 10.1016/j.imu.2022.101038 [Article Type] Research article
SARS-CoV-2 spike protein detection using slightly tapered no-core fiber-based optical transducer약간 테이퍼진 노코어 광섬유 기반 광 변환기를 사용한 SARS-CoV-2 스파이크 단백질 검출Article Published on 2022-08-062022-09-11 Journal: Mikrochimica Acta [Category] SARS, 치료기술, [키워드] ACE2 adopted Antigen binding buffer cause changes in Concentration COVID-19 cross-reactivity demonstrated Detection sensitivity effective expected facilitate fiber lAbel medium MERS MERS-CoV modulation No-core fiber optical Optical fiber Optical fiber biosensor platform probe Protein protocol reconstructed refractive index reproducibility Saliva SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein selective Spike protein Tapered optical fiber. Transmission was selected [DOI] 10.1007/s00604-022-05413-3 PMC 바로가기 [Article Type] Article
Interim Recommendation of the Advisory Committee on Immunization Practices for Use of the Novavax COVID-19 Vaccine in Persons Aged ≥18 years – United States, July 202218세 이상인 사람의 Novavax COVID-19 백신 사용에 대한 예방접종 관행에 대한 자문 위원회의 임시 권고 - 미국, 2022년 7월Article Published on 2022-08-052022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 변종, [키워드] 95% CI Administered Adults Alpha variant assessments association authorization B.1.1.7 causal relationship cause Chain Reaction circulating Committee COVID-19 COVID-19 vaccine dose drug Efficacy efficacy analysis Emergency Emergency use authorization EUA FDA flexibility food Food and Drug Administration immunization infection with SARS-CoV-2 information Interim Matrix-M myocarditis Novavax NVX-CoV2373 per-protocol Pericarditis Person polymerase chain reaction Practice predominant PROTECT Protein provide reported reverse transcription Reverse transcription-polymerase chain reaction RT-PCR SARS-CoV-2 symptomatic symptomatic COVID-19 United States vaccination Vaccine vaccine efficacy variant virus [DOI] 10.15585/mmwr.mm7131a2 PMC 바로가기 [Article Type] Article