Conserved epitopes dominate cross-CD8+ T-cell responses against influenza A H1N1 virus among Asian populationsClinical Trial Published on 2013-08-012023-06-25 Journal: European Journal of Immunology [Category] 신종인플루엔자, [키워드] CD8+ T cell conserved epitope immunodominance influenza A H1N1 virus TCR usage. [DOI] 10.1002/eji.201343417 [Article Type] Clinical Trial
Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell DeterminantResearch Article Published on 2008-10-242022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] alteration amino acid substitution Analysis antigen-specific T cell association Author CD8+ T cell changes in clinical disease complex Complex molecule conformation Consensus Critical CTL cytotoxic determinant Disease progression Diseases elicit Enhancing epitope escape expressed functional Hepatitis histocompatibility HIV immune response immune responses immunodominant Infected Local Major memory MHC class I mice molecular basis motif mouse hepatitis mutated Mutation natural infection occur pathogen peptide performed prevention PROTECT Protective recombinant residue response significantly higher stability Subdominant T cell T cell epitope T cell response tumor immunity Vaccine development viral infection virus wildtype [DOI] 10.1371/journal.ppat.1000186 PMC 바로가기 [Article Type] Research Article