Genetic Diversity of Plasmodium vivax Cysteine-Rich Protective Antigen (PvCyRPA) in Field Isolates from Five Different Areas of the Brazilian Amazon브라질 아마존의 다섯 개 지역에서 채취한 현장 분리주에서의 플라스모디움 비박스 시스테인 풍부 보호 항원(PvCyRPA)의 유전적 다양성Article Published on 2021-10-212024-08-08 Journal: Genes [Category] 말라리아, [키워드] Brazilian Amazon genetic diversity malaria Plasmodium vivax prediction PvCyRPA vaccine candidate [DOI] 10.3390/genes12111657 PMC 바로가기 [Article Type] Article
The Rare, the Best: Spread of Antimalarial-Resistant Plasmodium falciparum Parasites by Anopheles Mosquito Vectors희귀하고 최고의: 아노펠레스 모기 매개체에 의한 항말라리아 내성 플라스모디움 팔시파룸 기생충의 확산Research Article Published on 2021-10-202024-08-08 Journal: Microbiology Spectrum [Category] 말라리아, [키워드] Anopheles Antimalarials genetic diversity malaria Mosquito Plasmodium falciparum resistance Transmission [DOI] 10.1128/Spectrum.00852-21 PMC 바로가기 [Article Type] Research Article
Coronavirus Disease 2019 Vaccine Impact on Rates of Severe Acute Respiratory Syndrome Coronavirus 2 Cases and Postvaccination Strain Sequences Among Health Care Workers at an Urban Academic Medical Center: A Prospective Cohort StudyMajor Articles Published on 2021-10-172022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] acute respiratory syndrome antibody escape mutations Asymptomatic Breakthrough infection Community Confidence intervals confirmed case coronavirus coronavirus 2 Coronavirus disease 2019 COVID-19 COVID-19 vaccine decrease dose dropped first dose genetic diversity Genome HCW HCWs Health care worker Impact infection control infections initial injection isolate Latinx mRNA-1273 Mutation occurred of BNT162b2 Older positive Prevalence Prospective prospective cohort study Rate rate ratio respiratory Result SARS-CoV-2 SARS-CoV-2 infections selection pressure sequence sequenced Spike protein strain urban vaccination Vaccine vaccine doses vaccine trial viral evolution Weekly Whole genome sequencing with COVID-19 worker [DOI] 10.1093/ofid/ofab465 PMC 바로가기 [Article Type] Major Articles
Single-genome sequencing reveals within-host evolution of human malaria parasitesArticle Published on 2021-10-132024-08-28 Journal: Cell Host & Microbe [Category] 말라리아, [키워드] de-novo mutations genetic diversity malaria malaria low parasitaemia Parasite mutations Parasite relatedness Plasmodium falciparum Plasmodium vivax single-cell sequencing within-host evolution.
Phylogenomic analysis and Mycobacterium tuberculosis antibiotic resistance prediction by whole-genome sequencing from clinical isolates of Caldas, ColombiaResearch Article Published on 2021-10-072022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] Analysis Antibiotic resistance bioinformatic analysis contributed COVID-19 pandemic Culture database death DNA extraction drug drug resistance epidemiological Follow-up genetic diversity genomic Genomic analysis Harlem highest Illumina HiSeq 2500 incidence Infectious disease involved isolate Lineage mechanism medium molecular Mutation Mycobacterium tuberculosis pathogen Patient performed phenotype platform positive Preliminary data provide responsible strain subsequent Transmission dynamics Tuberculosis was obtained was performed WGS Whole genome sequencing whole-genome sequencing [DOI] 10.1371/journal.pone.0258402 PMC 바로가기 [Article Type] Research Article
Biological Significance of the Genomic Variation and Structural Dynamics of SARS-CoV-2 B.1.617Microbiology Published on 2021-10-072022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute respiratory syndrome amino acid change analyzed B.1.617 B.1.617.2 binding ability Biological biological significance circulating coronavirus country COVID-19 pandemic Deletion Dynamics Follow-up Frequency genetic diversity Genome genomic variation Haplotype Haplotype network increasingly India indicated involved L452R lifted Lineage measure molecular evolution mutant Mutation N501Y nonstructural proteins P681R pandemic Positive selection predominant prevalent reported SARS-CoV-2 sequence sequenced Significance Single nucleotide polymorphism SNPs Spread Structural analysis structural proteins Substitution tertiary structure the S protein the vaccine tracing variant viral genome [DOI] 10.3389/fmicb.2021.750725 PMC 바로가기 [Article Type] Microbiology
Characterizing the genomic variation and population dynamics of Plasmodium falciparum malaria parasites in and around Lake Victoria, Kenya케냐 빅토리아 호수 안팎에서 Plasmodium falciparum malaria 기생충의 게놈 변화와 인구 역학 특성Article Published on 2021-10-062022-10-04 Journal: Scientific Reports [Category] 말라리아, 바이오마커, [키워드] African analyses Analysis Baseline assessment Biomarker clearance Cluster combination therapy contribute drug resistance East Efficacy Epidemiology Frequency genetic data genetic diversity genomic genomic variation Genomics Illumina isolate Kenya Lake Lake Victoria lineages malaria Mutation P. falciparum parasite Plasmodium falciparum Population populations provide Region Sequencing Structural variation Transmission WGS [DOI] 10.1038/s41598-021-99192-1 PMC 바로가기 [Article Type] Article
Molecular Characterization of Blastocystis from Animals and Their Caregivers at the Gdańsk Zoo (Poland) and the Assessment of Zoonotic TransmissionArticle Published on 2021-09-302023-08-29 Journal: Biology [Category] E형 간염, [키워드] animals Blastocystis genetic diversity humans molecular phylogeny Poland Subtypes [DOI] 10.3390/biology10100984 PMC 바로가기 [Article Type] Article
Genomic Characterization of Diverse Bat Coronavirus HKU10 in Hipposideros BatsArticle Published on 2021-09-292022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Accessory genes addition Alpha alphacoronavirus Aselliscus bat bat coronavirus bat coronavirus HKU10 bats betacoronaviruses Cell cell tropism characterization China circulating collected Continuous coronavirus Coronaviruses correlated defined demonstrated distribution Evolution expand fecal samples full-length genome Genes genetic diversity Genotype Guangxi Hainan Hipposidero interspecies transmission investigated lentivirus lineages much higher New novel lineage Phylogenetic analysis polyproteins positive reported reservoir reverse transcriptase PCR Rousettus screened selective sequenced spike gene strain variant variety virus zoonotic disease [DOI] 10.3390/v13101962 PMC 바로가기 [Article Type] Article
RADx Variant Task Force Program for Assessing the Impact of Variants on SARS-CoV-2 Molecular and Antigen TestsArticle Published on 2021-09-292022-10-31 Journal: IEEE Open Journal of Engineering in Medicine and Biology [Category] COVID-19, [키워드] acceleration activity Antigen approach Assessing B.1.1.7 B.1.617.2 CDC COVID-19 Delta determine diagnostic diagnostic tests Evolution FDA force genetic diversity Human Impact in silico in vitro in vitro diagnostics Lineage lineages molecular monitoring Mutation mutations offer Prevalence Program Rapid SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 variant Test therapy Vaccines variants of concern virus working [DOI] 10.1109/OJEMB.2021.3116490 PMC 바로가기 [Article Type] Article