highly pathogenic
[용어속성] Term
Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus)
SARS-CoV-2(COVID-19 바이러스)의 게놈 돌연변이 및 단백질 2차 구조 및 용매 접근성의 변화
Article
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
Analysis
caused
changes
changes in
coding gene
coding genes
coding region
coding regions
coronavirus
COVID-19 pandemic
COVID-19 virus
D614G
Data mining
dataset
deep learning
Evolution
facilitate
genomic
genomic mutation
genomic mutations
highly pathogenic
Intervention
Mutation
mutation D614G
ORF10
ORF6
ORF7a
ORF7b
pandemic
Point mutation
point mutations
predicted
prediction
Protein
researchers
respiratory
respond
SARS-CoV-2
secondary structure
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
solvent
Spike protein
Spread
tracing
Transmission
unlikely
Vaccine
Viral
viral genome sequences
virus
virus spike protein
[DOI] 10.1038/s41598-021-83105-3 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41598-021-83105-3 PMC 바로가기 [Article Type] Article
The interplay between emerging human coronavirus infections and autophagy
신종 코로나바이러스 감염과 자가포식 사이의 상호작용
Review
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
applicability
approved
autophagic
autophagy
breath
cellular
concerning
coronavirus
coronavirus disease
Coronavirus disease 2019
Coronavirus infection
CoV infection
COVID-19
drugs targeting
Evidence
HCoV
HCoVs
highly pathogenic
human coronavirus
induce
Infection
MERS
MERS-CoV
MHV
Middle East
Middle East respiratory syndrome Coronavirus
mouse hepatitis
mouse hepatitis virus
outbreak
pandemic
Potential treatment
promote
provided
Replication
respiratory
respiratory syndrome coronavirus
SARS-CoV
SARS-CoV-2
severe acute respiratory syndrome Coronavirus
stimulate
target cell
target cells
Viral
viral propagation
[DOI] 10.1080/22221751.2021.1872353 PMC 바로가기 [Article Type] Review
[DOI] 10.1080/22221751.2021.1872353 PMC 바로가기 [Article Type] Review
Mechanisms of Coronavirus Nsp1-Mediated Control of Host and Viral Gene Expression
Review
[키워드] activity
acute respiratory syndrome
Amino acid
antiviral responses
biological function
cell interaction
cellular
cleavage
contribute
Control
Coronaviruses
CoVs
disrupt
endonucleolytic cleavage
evade
function
Gene Expression
genomes
highly pathogenic
Host
host gene expression
host gene expression suppression
host mRNA
human coronavirus
identity
involved
mechanism
MERS-CoV
Middle East
mRNA
mRNA degradation
nonstructural protein 1
nsp1
pathogenic
SARS-CoV
SARS-CoV-2
suppresse
syndrome
translation
translational suppression
viral mRNA
viral pathogenicity
Viral protein
viral replication
virulence
virulence factor
virus
virus pathogenesis
[DOI] 10.3390/cells10020300 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/cells10020300 PMC 바로가기 [Article Type] Review
A Neutralization Assay Based on Pseudo-Typed Lentivirus with SARS CoV-2 Spike Protein in ACE2-Expressing CRFK Cells
Article
[키워드] 293T
ACE2
acute respiratory syndrome
angiotensin-converting enzyme 2
anti-SARS-CoV-2
anti-spike antibody
Antisera
antiviral inhibitor
applied
Cell
coated with
contribute
convalescent
coronavirus
COVID-19
CrFK
CRFK Cell
Dilution
effective
embryonic kidney
ENhance
evaluate
HEK293T
highly pathogenic
HIV
host cell
human convalescent sera
IC50
IgA
IgG
IgM
Immunoglobulin
immunoglobulin A
IMPROVE
Infection
inhibitor
inhibitory concentration
kidney
lentivirus
mAbs
methodology
monoclonal
monoclonal antibody
Neutralization assay
neutralizing monoclonal antibody
pseudo-typed lentivirus
reagent
required
researcher
SARS CoV-2
SARS-CoV-2
spike
Spike protein
Spread
the SARS-CoV-2
virus
Virus neutralization
zoonotic
[DOI] 10.3390/pathogens10020153 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/pathogens10020153 PMC 바로가기 [Article Type] Article
Remdesivir: From Ebola to COVID-19
렘데시비르: 에볼라에서 코로나19까지
Review
[키워드] acute respiratory syndrome
adenosine
Adenosine analogues
animal coronavirus
Animal coronaviruses
antiviral activity
antiviral drug
antiviral drugs
antiviral therapy
approved
candidate
changed
China
clinical study
coronavirus
Coronavirus infection
Coronavirus infections
COVID-19
disease
double blind
drug
Ebola
Ebola virus
Efficacy
Epidemic
HCoV
Health
highly pathogenic
hospitalized patient
hospitalized patients
hosts
Human
human coronavirus
human coronaviruses
human-to-human transmission
in vitro
In vitro studies
in vitro study
inhibit
initial
initiated
MERS
Middle East
Middle East respiratory syndrome
Mild
molecular mechanism
mortality rate
mortality rates
nucleotide
outbreak
Pathogens
Patient
placebo controlled trial
preclinical studies
Randomized
Remdesivir
Replication
respiratory
Respiratory tract diseases
RNA
RNA dependent RNA polymerase
SARS-CoV-2
SARS-CoV-2 coronavirus
Severe acute respiratory syndrome
shortening
shown
syndrome
thought
Time to recovery
treated
Treatment
Trial
upper respiratory tract
USA
virus
zoonotic infection
zoonotic infections
[DOI] 10.1016/j.bbrc.2020.11.043 PMC 바로가기 [Article Type] Review
[DOI] 10.1016/j.bbrc.2020.11.043 PMC 바로가기 [Article Type] Review
Diamond Light Source: contributions to SARS-CoV-2 biology and therapeutics
다이아몬드 광원: SARS-CoV-2 생물학 및 치료제에 대한 기여
Article
[키워드] Antibody structure
Antiviral
applied
approach
approved
Biologicals
clinically
Coronaviruses
COVID-19
Cryo-electron microscopy
cryo-EM
Crystallography
develop
diamond
drug
Drug discovery
Drug repurposing
drugs
effective
Fragment based drug discovery
highly pathogenic
LIGHT
monoclonal antibody
monoclonal antibody therapy
NMR
pandemic
Protein
public health
released
repurposing
Research
response
Safe
SARS-CoV-2
SARS-CoV-2 biology
SARS-CoV-2 sequence
sequence
Source
structural biology
Structure-based drug design
the SARS-CoV-2
therapy
treat
Treatment
Vaccine
Vaccine development
[DOI] 10.1016/j.bbrc.2020.11.041 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.bbrc.2020.11.041 PMC 바로가기 [Article Type] Article
HTCC as a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoV
SARS-CoV-2 및 MERS-CoV의 고분자 억제제로서의 HTCC
Article
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
antiviral activity
bats
block
Care
characterization
China
chitosan
chloride
circulating
Cluster
Compound
Coronaviridae
coronavirus
demonstrated
Entry
epithelia
escaped
ex vivo model
HCoV
HCoV-229E
HCoV-HKU1
HCoV-NL63
HCoV-OC43
Health
Health care
highly pathogenic
HKU1
host cell
HTCC
human airway
human airway epithelia
human coronavirus
humans
in vitro
infect
information
inhibited
inhibition
inhibitor
Interaction
life-threatening
Local
measure
mechanism
mechanism of action
member
MERS
MERS-CoV
Middle East
Middle East respiratory syndrome Coronavirus
multiorgan failure
NL63
Novel coronavirus
OC43
pandemic
pathogen
Polymer
Rapid
Research
respiratory
respiratory infection
respiratory syndrome coronavirus
S protein
SARS-CoV-2
SARS-COV-2 infection
Seven
severe acute respiratory syndrome Coronavirus
Spread
the S protein
virus
virus entry
viruses
[DOI] 10.1128/JVI.01622-20 PMC 바로가기 [Article Type] Article
[DOI] 10.1128/JVI.01622-20 PMC 바로가기 [Article Type] Article