A combined strategy to detect plasma samples reliably with high anti-SARS-CoV-2 neutralizing antibody titers in routine laboratories일상적인 실험실에서 높은 항-SARS-CoV-2 중화 항체 역가로 혈장 샘플을 안정적으로 검출하기 위한 결합된 전략Article Published on 2021-11-012022-09-11 Journal: Journal of Clinical Virology [Category] MERS, SARS, 진단, 치료기술, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 IgG approach BSL-2 Cell Convalescent plasma therapy COVID-19 criterion detect detection Detection of anti-SARS-CoV-2 neutralizing antibodies Effectiveness example feasible Humoral immunity Laboratory long-lasting NAb NAb assay NAb assays NAb titer NAb titers NAbs neutralization test Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody titer plasma plasma sample plasma samples reduce risk SARS-CoV-2 specimens surrogate virus neutralization test sVNT sVNT assay symptom onset time-consuming virus neutralization test [DOI] 10.1016/j.jcv.2021.104984 PMC 바로가기 [Article Type] Article
Comparison of Persistent Symptoms After COVID-19 and Other Non-SARS-CoV-2 Infections in ChildrenPediatrics Published on 2021-10-292022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute COVID-19 addition affected age anosmia/dysgeusia change children clinical clinical sequelae cognitive cohort study conducted consequence controls coughing COVID COVID patient COVID-19 COVID-19 patient cut-off difference enrolled etiologies fatigue Fever follow-up time group headache Headaches identify Inclusion Infection IQR irritability Latvia less long-lasting loss of taste majority MOST nocturnal Other Patient pediatric pediatrics persistence persistent regression analysis reported Research rhinorrhea SARS-CoV-2 SARS-COV-2 infection significantly study population survivor sweating Symptom symptom onset Symptoms the patient university Viral with COVID-19 [DOI] 10.3389/fped.2021.752385 PMC 바로가기 [Article Type] Pediatrics
Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccinesReview Article Published on 2021-10-282022-10-04 Journal: NPJ Vaccines [Category] 치료제, [키워드] antiviral response downstream signaling pathway effective elicit immune immune defense immune responses Infectious diseases invading pathogen involved knowledge ligands long-lasting mechanism microbial pathogen-associated molecular patterns receptor receptors Signaling Surveillance TLR TLRs Toll-like receptor Transcriptional upregulation transmembrane protein triggered understanding Vaccine Vaccines viral pathogen virus [DOI] 10.1038/s41541-021-00391-8 PMC 바로가기 [Article Type] Review Article
Case Report: Nintedaninb May Accelerate Lung Recovery in Critical Coronavirus Disease 2019Medicine Published on 2021-10-282022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress Administered antifibrotic therapy appear approved ARDS characterized chest CT scan clinical compassionate use contributed coronavirus disease (COVID-19) Coronavirus disease 2019 COVID-19 dosage ECMO endothelial event Factor fibroblast Follow-up functional growth factor ILD Interstitial lung disease intubation long-lasting lung Lung function Lung inflammation Lung recovery mechanism modulate molecular Nintedanib obese patient Patient patients with COVID-19 Pneumonia receptor reflected respiratory dysfunction Respiratory function severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe COVID-19 Support Survivors syndrome systemic inflammation target targeted therapy Treatment Trial Vascular withdrawn [DOI] 10.3389/fmed.2021.766486 PMC 바로가기 [Article Type] Medicine
The State of Mind of Health Care Professionals in Light of the COVID-19 Pandemic: Text Analysis Study of Twitter DiscoursesOriginal Paper Published on 2021-10-222022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, SARS, [키워드] accounted active learning affected Algorithm analyzed association Burnout Care caused changes in confirmed cases COVID-19 COVID-19 pandemic decrease defined described discourse distribution Effect Emotion analysis emotional exceeded expressed expressing extreme Factor fatigue fraction hcp Health Health care health care professionals Implications increase in indicate individual intensity labeling lack LIGHT long-lasting Longitudinal data longitudinal study machine learning mental health Mental health disorder mind morbidity MOST objective organization organizations pandemic pathway Population Prevent professional profiles resource Result sentiment analysis social media Spearman correlation coefficient state Support text timeline Topic topic analysis Twitter Volume was selected [DOI] 10.2196/30217 PMC 바로가기 [Article Type] Original Paper
Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long COVIDResearch Article Published on 2021-10-222022-10-30 Journal: JCI Insight [Category] COVID-19, MERS, SARS, [키워드] association bacterial composition cause caused chronic fatigue syndrome collected Confirmed contributed covariate COVID COVID-19 COVID-19 pandemic COVID-19 symptom disease dysfunction identify immune dysregulation individual Infection Inflammation Long long-lasting LPS metagenomic sequencing Microbiome microbiota Neurological disorders Patient presenting Prevotella random SARS-CoV-2 significantly higher Swab Symptom symptomatic Symptoms the patient thought was determined with COVID-19 [DOI] 10.1172/jci.insight.152346 PMC 바로가기 [Article Type] Research Article
De Novo and Relapsing Glomerulonephritis following SARS-CoV-2 mRNA Vaccination in Microscopic PolyangiitisCase Report Published on 2021-10-222022-11-01 Journal: Case Reports in Nephrology [Category] COVID-19, [키워드] BNT162b2 mRNA vaccine Case report coronavirus de novo disease Disease activity female patient glomerular Glomerulonephritis Kidney disease long-lasting macrohematuria Microscopic mRNA mRNA vaccine one patient pandemic Patient patients polyangiitis receiving recent relapsing renal SARS-CoV-2 second vaccination the SARS-CoV-2 therapy vaccination Vaccine vaccine dose Vasculitis [DOI] 10.1155/2021/8400842 PMC 바로가기 [Article Type] Case Report
The Role of Bronchoscopy in the Diagnosis and Management of Patients with SARS-Cov-2 InfectionReview Published on 2021-10-192022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] aerosol-generating procedure bronchoscopy coronavirus disease COVID-19 decrease diagnostic Diagnostic strategies Evidence Healthcare provider increased risk indication Infection infectious risk long-lasting management measure pandemic Patient raised required risk role significantly Spread Standard of care therapeutic indication [DOI] 10.3390/diagnostics11101938 PMC 바로가기 [Article Type] Review
Cytidine deamination-induced perpetual immunity to SAR-CoV-2 infection is a potential new therapeutic targetSAR-CoV-2 감염에 대한 시티딘 탈아미노화 유도 영구 면역은 잠재적인 새로운 치료 표적입니다Review Published on 2021-10-152022-09-10 Journal: International Journal of Medical Sciences [Category] MERS, SARS, 변종, [키워드] antibody Asymptomatic cause causes cell types contributing to COVID 19 COVID-19 cytidine Cytidine deaminase develop focus generate Human immune cell type immune cell types immune response immune responses immune system Immunity Infection initiate long-lasting molecular New variants of Coronavirus Perpetual immunity provided reason Research responses SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 virus SRS-CoV-2 Survivors symptomatic people the SARS-CoV-2 virus therapeutic target vaccination Variation variations viral strains virus [DOI] 10.7150/ijms.61779 PMC 바로가기 [Article Type] Review
COVID-19 vaccination program in the mainland of China: a subnational descriptive analysis on target population size and current progressResearch Article Published on 2021-10-152022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, MERS, [키워드] Administered Beijing characterized China Complete conducted coronavirus disease Coverage COVID-19 COVID-19 vaccination Descriptive analysis disparity division dose expected Government group highest Local long-lasting Measures Novel coronavirus disease 2019 pandemic Result Shanghai substantial risk supplementary material Support target population vaccination Vaccine [DOI] 10.1186/s40249-021-00909-1 PMC 바로가기 [Article Type] Research Article