Comparison of initial clinic characteristics of hospitalized patients in Suzhou City during the COVID-19 Omicron wave with ancestral variant waveCOVID-19 오미크론 파동 동안 쑤저우시 입원 환자의 초기 임상 특성과 조상 변이 파동의 비교Comparative Study Published on 2022-01-012022-09-11 Journal: Therapeutic Advances in Respiratory Disease [Category] SARS, 변종, [키워드] Analysis assessment B.1.1.529 Characteristics chi-square test China city Clinical data clinical feature Cluster Cohort cohort study collected comparable comparison Comparisons Computed tomography COVID-19 crazy-paving pattern EHR Electronic health record failure Fever Fisher exact test GGOs Ground-glass opacities ground-glass opacity had more Health health record Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Infection initial less Logistic regression analysis lower risk lung Mann-Whitney U test Multiple logistic regression analysis multivariable logistic regression Multivariable logistic regression analysis occurred omicron Omicron variant outbreak performed Pneumonia provided radiology reduced responsible risk SARS-CoV-2 variant severity SOFA suffered the epidemic the SARS-CoV-2 variant [DOI] 10.1177/17534666221110346 PMC 바로가기 [Article Type] Comparative Study
Colchicine use in patients with COVID-19: A systematic review and meta-analysisCovid-19 환자의 콜히친 사용 : 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-12-282022-09-10 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, 치료제, [키워드] 95% CI Admissions analyzed Care Clinical outcome Colchicine COVID-19 COVID-19 patient COVID-19 pneumonia Cytokines determine Efficacy hazard ratio ICU ICU admission ICU admissions identify individuals with COVID-19 inflammasome signaling inhibit intensive care intensive care unit Long-term care lower risk mechanical ventilation mechanism Meta-analysis Mortality no statistical difference Odds ratio outcome Patient patients patients with COVID-19 Pneumonia proinflammatory cytokines RCT RECOVERY trial reduce reference reported Result risk risk ratio screened searched systematic review the disease Treatment Trial [DOI] 10.1371/journal.pone.0261358 PMC 바로가기 [Article Type] Meta-Analysis
Genetically Predicted Higher Educational Attainment Decreases the Risk of COVID-19 Susceptibility and Severity: A Mendelian Randomization StudyPublic Health Published on 2021-12-232022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 95% CI alcohol attainment body mass index confounding factors controls correlated COVID-19 COVID-19 susceptibility decrease disease educational attainment Effect genetic instrument Genome-wide association study GWAS Hospitalization indicated initiative inverse lower risk mendelian randomization morbidity and mortality Multivariable MR observational study outcomes performed physical activity Population predicted primary analysis provided public health R software resource Result risk Sedentary behavior severity severity of COVID-19 smoking statistical analysis susceptibility [DOI] 10.3389/fpubh.2021.731962 PMC 바로가기 [Article Type] Public Health
Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients외래 환자에서 중증 코로나19로의 진행을 예방하기 위한 조기 렘데시비르Randomized Controlled Trial Published on 2021-12-222022-09-25 Journal: The New England Journal of Medicine [Category] Fulltext, SARS, 신약개발, 임상, 진단, 치료제, [키워드] 95% CI 95% confidence interval Adverse adverse event age assigned Clinical outcome condition conducted coronavirus disease Course death Diabetes Mellitus died Disease progression dose double-blind efficacy end point end point EudraCT event hazard ratio high risk Hispanic Hospitalization hypertension IMPROVE Intravenous remdesivir Latinx lower risk Medical conditions obesity occurred Outpatient Patient patients hospitalized Placebo placebo-controlled trial Prevent progression randomization Randomized Randomly receive Remdesivir Result risk factor safety profile symptom onset symptomatic the patient the placebo group women [DOI] 10.1056/NEJMoa2116846 PMC 바로가기 [Article Type] Randomized Controlled Trial
Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and Outcomes in Patients Hospitalized for COVID-19Observational Study Published on 2021-12-212022-10-05 Journal: Journal of the American Heart Association [Category] 임상, [키워드] 95% CI ACE ACE inhibitors ACEi/ARB adjusted hazard ratio Affect Angiotensin II angiotensin receptor blocker Angiotensin receptor blockers angiotensin-converting enzyme 2 angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors association biomarkers of inflammation blood pressure C-reactive protein cell entry receptor clinical COVID-19 COVID‐19 death deaths dialysis dose examined Hospitalization In-hospital In-hospital death inclusion criteria Inflammation lower risk Measures mechanical ventilation modulating Mortality multivariable analysis need for dialysis outcome outcomes Patient patients hospitalized receptor Registration required Result SARS-CoV2 serum creatinine symptomatic thought Treatment Trial Ventilation [DOI] 10.1161/JAHA.121.023535 PMC 바로가기 [Article Type] Observational Study
Mediterranean Diet a Potential Strategy against SARS-CoV-2 Infection: A Narrative ReviewReview Published on 2021-12-202022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] acute respiratory syndrome benefit Cancer cardiovascular diseases coronavirus coronavirus disease COVID-19 Critical diet Effect fatty acids Health immune system incidence infection with SARS-CoV-2 Inflammation lower risk Mediterranean diet Minerals narrative nutrition overall mortality pandemic Population positive Potential Probability protective effect protective role reduce review risk risk factor SARS-CoV-2 Strategy the disease vitamins [DOI] 10.3390/medicina57121389 PMC 바로가기 [Article Type] Review
Mental Health and Associated Demographic and Occupational Factors among Health Care Workers during the COVID-19 Pandemic in LatviaArticle Published on 2021-12-182022-10-30 Journal: Medicina [Category] Coronavirus, SARS, [키워드] 95% CI adverse outcome adverse outcomes analysed Anxiety anxiety symptoms Care cohort study Contact COVID-19 COVID-19 pandemic cross-sectional Data analysis demographic demographics Depression evaluate Factor First wave Frequency GAD-7 general practitioner had more HCW HCWs Health Health care Health care worker health care workers higher risk hospital impacted information Latvia Logistic regression lower risk material mental health occupational Older participant Patient PHQ-9 Quantitative questionnaire reported SPSS Symptom symptoms of depression was performed worker working [DOI] 10.3390/medicina57121381 PMC 바로가기 [Article Type] Article
The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysisSystematic Review Published on 2021-12-142022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] analyzed association collecting data conducted contribute coronavirus disease COVID-19 COVID-19 patient COVID-19 patients COVID-19; therapeutic plasma exchange; cytokine storm; treatment critical condition Critically ill Cytokine storm lower risk Meta-analysis Mortality mortality rate Patient patients treated potential benefit reducing reduction risk Standard of care suggested Therapeutic plasma exchange TPE treated Treatment Web of Science [DOI] 10.12688/f1000research.74972.1 PMC 바로가기 [Article Type] Systematic Review
Psychological Impact of the COVID-19 Pandemic on Healthcare Professionals in Tunisia: Risk and Protective FactorsPsychology Published on 2021-12-142022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] 95% CI Anxiety Care changes collected conducted coronavirus disease COVID-19 COVID-19 pandemic cross-sectional Depression equipment evaluate exacerbating example Factor Factors female gender female participant First wave Generalized groups had more hcp Health Healthcare professional healthcare professionals identify Impact IMPROVE information Insomnia Insomnia Severity Index interfere Logistic regression lower risk magnitude male participant Measures mental health Nurse Nurses outcome pandemic patients Personal protective equipment physical activity physician Physicians professional proportion Protective Protective factors provided psychiatric history Psychological outcome Psychological outcomes psychological support psychological symptom psychological symptoms questionnaire risk factor Risk factors Symptom women [DOI] 10.3389/fpsyg.2021.754047 PMC 바로가기 [Article Type] Psychology
Statin Use and In-hospital Mortality in Patients with COVID-19 and Coronary Heart DiseaseArticle Published on 2021-12-132022-10-04 Journal: Scientific Reports [Category] 임상, 치료제, [키워드] 95% CI adjusted adjusted hazard ratio Analysis anti-inflammatory effect attenuate benefit Cardiology CHD Comorbidity Coronary coronavirus disease COVID-19 COVID-19 patient Diseases enrolled heart hospital in-hospital mortality increased mortality inflammatory markers lower risk median Medical research mortality risk multivariable Cox regression Older Patient patients proinflammatory Propensity score propensity score matching reduced statin survival with COVID-19 worsening Wuhan, China [DOI] 10.1038/s41598-021-02534-2 PMC 바로가기 [Article Type] Article