The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins
SARS-CoV-2 스파이크 단백질은 포유류 ACE2 단백질에 대해 광범위한 친화성을 가지고 있습니다.
Research Article
Published on
Journal: PLoS Biology [Category] Biology and Life Sciences, COVID-19, Fulltext, SARS, 조류인플루엔자,
Journal: PLoS Biology [Category] Biology and Life Sciences, COVID-19, Fulltext, SARS, 조류인플루엔자,
[키워드] absence
ACE2
ACE2 protein
ACE2 proteins
ACE2 receptor
ACE2 receptors
addition
aligned
Amino acid
amino acid residue
amino acid residues
amino acids
angiotensin
bat
bat ACE2
bats
bioinformatics
cattle
Cell
changed
China
circulating
Combination
coronavirus
coronavirus disease
Coronavirus disease 2019
coronaviruses SARS-CoV
COVID-19
Divergence
examined
global mortality
glycoprotein
Host
host tropism
Human
human Angiotensin-converting enzyme
Human angiotensin-converting enzyme 2
human populations
humans
indicate
infect
Infection
intermediate host
investigated
Live virus
livestock
mammalian
Mutagenesis
pandemic
potential risk
Protein
Proteins
RaTG13
receptor binding site
receptors
reservoirs
SARS Coronavirus
SARS coronavirus 2
SARS-CoV
SARS-CoV-2
SARS-CoV-2 receptor
sequence
sequence similarity
spike
spike glycoprotein
Spike protein
the Spike
thought
tropism of SARS-CoV-2
Viral
viral entry
virus
virus spread
viruses
wildlife
zoonotic
zoonotic transmission
[DOI] 10.1371/journal.pbio.3001016 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pbio.3001016 PMC 바로가기 [Article Type] Research Article