Medical Research Council – Page 12 – Communicable Diseases Research

Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study

저소득 및 중간 소득 국가의 HIV, 결핵, 말라리아에 대한 코로나19 대유행의 잠재적 영향: 모델링 연구

Article

Published on 2020-07-132022-10-30
Journal: The Lancet. Global health [Category] COVID-19, 말라리아,

Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic

Article

Published on 2020-07-012022-10-30
Journal: The lancet. Psychiatry [Category] COVID-19, Fulltext, MERS,

[키워드] 95% CI acute illness acute respiratory syndrome age Agitation Anxiety Anxiety Disorder Canada Case report caused China Chinese classification Confusion coronavirus Coronavirus infection Course COVID-19 COVID-19 pandemic database delirium Depression diagnose died discharge effect size employment Encephalitis Encephalopathy Evidence examined excluded fatigue finding FIVE follow-up time foundation France funding Hong Kong hospital hypoxic ICD-10 impairment inclusion criteria independent index indicated indirect effect individual infection with SARS-CoV-2 Insomnia intensive care irritability Japan laboratory-confirmed literature Mania Medical Research Council medium memory mental health mental illness MERS MERS coronavirus MERS-CoV Meta-analysis meta-analytical Middle East Neurological complication Neuropsychiatric NHS NIHR Nursing outcome outcomes participant Patient patients patients with COVID-19 patients with SARS peer-reviewed study physical distancing measure Post-traumatic stress disorder Prevalence proportion Psychiatric PsycINFO quarantine random-effects model ranged reported researcher returned SARS Coronavirus SARS-CoV SARS-CoV-2 Saudi Arabia searched Self-isolation Seven Singapore sleep disorder South Korea Stage stratified Symptom syndrome systematic review the mean Trust University College London USA Wellcome Trust were assessed
[DOI] 10.1016/S2215-0366(20)30203-0 PMC 바로가기 [Article Type] Article

Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study

Article

Published on 2020-06-152022-10-30
Journal: The Lancet. Global health [Category] COVID-19, Fulltext, MERS,

[키워드] African age agency analysed assumed burden calculated cardiovascular disease China Chronic kidney disease chronic respiratory disease Clustering condition conditions confidence limit country COVID-19 defined Department determine development diabete diabetes disease estimate Factor female females finding FIVE Fractions frailty funding global pandemic groups Health health condition help high risk highest HIV/AIDS Hospital admission increased risk individual Interpretation interval male Medical Research Council Multimorbidity National obesity Older populations Prevalence prevalences public health risk risk factor severe COVID-19 severe disease Sex Socioeconomic deprivation starting point underlying condition understanding USA vaccinate was determined Wellcome Trust WHO
[DOI] 10.1016/S2214-109X(20)30264-3 PMC 바로가기 [Article Type] Article

Effects of non-pharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study

Article

Published on 2020-06-022022-10-29
Journal: The Lancet. Public Health [Category] COVID-19,

[키워드] 95% prediction interval acute respiratory syndrome Admission basic reproduction number Characteristics Combination Contact coronavirus COVID-19 COVID-19 cases Critical care death deaths decrease early stage Effect effective England Epidemic extreme finding funding Health Service health-care hospital ICU ICUs Intensive intensive care unit Intervention Ireland lockdown measure median Medical Research Council Older Patient physical distancing Prevent proportion reduce reducing repeated required SARS-CoV-2 Self-isolation shielding Support symptomatic cases the epidemic Transmission Transmission model Treatment Trigger
[DOI] 10.1016/S2468-2667(20)30133-X PMC 바로가기 [Article Type] Article

Estimates of the severity of coronavirus disease 2019: a model-based analysis

Article

Published on 2020-06-012022-10-29
Journal: The Lancet. Infectious Diseases [Category] COVID-19, MERS, SARS,

[키워드] adjusted age aggregate Analysis attack rate case fatality ratio China clinically collected coronavirus disease COVID-19 COVID-19 disease CrI cumulative death diagnosed died discharge distribution estimate estimates fatality finding funding Government group Health Hong Kong hospital hospital discharge hospitalisation hospitalised infected individual Infection International Laboratory Macau magnitude media Medical Research Council National occurred Older Older age onset of symptom outcome Patient PCR-confirmed Prevalence produced proportion provincial health commission reported risk of death robust severity stratified subset the mean website were used
[DOI] 10.1016/S1473-3099(20)30243-7 PMC 바로가기 [Article Type] Article

Infection prevention and control compliance in Tanzanian outpatient facilities: a cross-sectional study with implications for the control of COVID-19

Article

Published on 2020-05-062022-10-30
Journal: The Lancet. Global health [Category] COVID-19, Fulltext, MERS,

[키워드] age Analysis assistant association calculated challenge Characteristics collected Compliance coronavirus disease Council COVID-19 cross-sectional Department development domains equipment examined facility female finding for disinfection funding Health health system health worker hospitals hygiene implication improvement indication indications Infection prevention infection risks Interaction laboratory technician logistic regression models management medical doctors Medical Research Council Nurse Odds ratio outpatient consultation pandemic performed proportion randomised controlled trial regions significantly spreads Transmission Wellcome Trust
[DOI] 10.1016/S2214-109X(20)30222-9 PMC 바로가기 [Article Type] Article

Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial

항레트로바이러스 요법(REALITY)을 시작하는 아프리카의 심각한 면역 저하 HIV 감염 개인의 사망률에 대한 즉시 사용 가능한 보충 식품의 효과: 공개, 병렬 그룹, 무작위 대조 시험

Article

Published on 2018-04-102022-09-06
Journal: The Lancet. HIV [Category] Communicable Disease,

[키워드] 1:1 95% CI adverse event adverse events age analysed anti-infection Antiretroviral therapy ART assigned block size BMI body-mass body-mass index both groups CD4 cell Cell changes in children clinic visit Clinic visits computer-generated database Department development died Dispensing Effect eight Eligible participants Evidence evidence of finding funding global health GRADE greater hazard ratio high risk HIV infection hospital hypothesise Immunocompromised in both group individual individuals infected individuals infections Intention intention to treat Interaction ISRCTN ISRCTN registry Kenya log-rank Medical Research Council medication micronutrients Mortality no evidence of nutritional status Older Open-label outcome parallel-group participant Participants peanut per day Policy present Primary outcome Prophylaxis raltegravir randomisation randomised controlled trial Randomly ready-to-use therapeutic food reducing Registered reported Safety secondary Secondary outcomes Serious Adverse Event Serious Adverse Events significantly stratified sub-Saharan Africa Symptom Trial Uganda vital status weight weight gain Wellcome Trust would increase Z score Zimbabwe
[DOI] 10.1016/S2352-3018(18)30038-9 PMC 바로가기 [Article Type] Article

Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomised controlled trial

HIV의 2차 치료를 위한 로피나비르 + 뉴클레오시드 역전사효소 억제제, 로피나비르 + 랄테그라비르 또는 로피나비르 단독요법(EARNEST): 무작위 대조 시험의 144주 추적 결과

Article

Published on 2018-01-012022-09-06
Journal: The Lancet. Infectious Diseases [Category] Communicable Disease,

[키워드] adverse event African AID analysed Analysis Antiretroviral therapy ART assigned best clinical Combination combination therapy completion computer-generated cooperation country criteria Developing development Efficacy eligibility European event finding FIVE Follow-up funding GRADE grade 3 group HIV-infected people inferiority inhibitor inhibitors intervention group ISRCTN Kenya less limit Lopinavir Medical Research Council Modification monotherapy no difference non-inferiority non-inferiority margin nucleoside offer offered outcome participant partnership Patient per day primary analysis Primary outcome protease Protease inhibitor raltegravir randomisation randomised controlled trial Randomly receive recent regimen regimens Registered Ritonavir screened sequence Serious Adverse Events Swedish Treatment treatment of HIV Trial two-sided α Uganda Viral Viral load viral loads Virological WHO WHO criteria WHO guideline Zimbabwe
[DOI] 10.1016/S1473-3099(17)30630-8 PMC 바로가기 [Article Type] Article

Nucleoside reverse-transcriptase inhibitor cross-resistance and outcomes from second-line antiretroviral therapy in the public health approach: an observational analysis within the randomised, open-label, EARNEST trial

공중 보건 접근법에서 뉴클레오시드 역전사효소 억제제 교차 내성 및 2차 항레트로바이러스 요법의 결과: 무작위, 공개, EARNEST 시험 내 관찰 분석

Articles

Published on 2017-05-082022-09-06
Journal: The Lancet. HIV [Category] Communicable Disease,

[키워드] AID Analysis Antiretroviral therapy ART assigned association baseline calculated clinical cooperation Cross-resistance Developing development European Evidence expected finding Follow-up funding Genotype genotypic greater impair inhibitor ISRCTN Lopinavir Medical Research Council monotherapy nucleoside Open-label outcome over partnership Patient patients with HIV predict predicted protease Protease inhibitor public health raltegravir randomised Randomised trial Randomly Registered Ritonavir sub-Saharan Africa Support Swedish tested therapy Treatment outcome Trial Viral Viral load Virological virological outcome virological outcomes WHO WHO criteria with HIV
[DOI] 10.1016/S2352-3018(17)30065-6 PMC 바로가기 [Article Type] Articles

Effect of immediate initiation of antiretroviral therapy on risk of severe bacterial infections in HIV-positive people with CD4 cell counts of more than 500 cells per μL: secondary outcome results from a randomised controlled trial

CD4 세포 수가 μL당 500개 이상인 HIV 양성인 사람의 중증 세균 감염 위험에 대한 항레트로바이러스 요법의 즉각적인 개시 효과: 무작위 대조 시험의 2차 결과 결과

Articles

Published on 2017-01-052022-09-06
Journal: The Lancet. HIV [Category] Communicable Disease,

[키워드] 95% CI AIDS allergy analysed Analysis Antiretroviral therapy ART assigned average Bacterial Bacterial infection Bacterial infections bacterial pneumonia Bildung caused CD4 cell Cell composite endpoint Cox proportional hazard Cox proportional hazards regression Cutoff death defined described disorder Effect Endpoint enrolled European explained extrapulmonary tuberculosis Factor finding Follow-up foundation funding hazard ratio Hospital admissions Immediate Increases increases in Infectious disease Infectious diseases median Medical Research Council multivariable analysis network neutrophil neutrophil count Patient Pneumonia randomised controlled trial recruited reduce reduced risk Registered required risk secondary outcome severity subgroup subgroups Trial Tuberculosis univariable analysis
[DOI] 10.1016/S2352-3018(16)30216-8 PMC 바로가기 [Article Type] Articles