Modeling the trend of coronavirus disease 2019 and restoration of operational capability of metropolitan medical service in China: a machine learning and mathematical model-based analysisResearch Published on 2020-05-062022-10-31 Journal: Global Health Research and Policy [Category] COVID-19, MERS, [키워드] 95% CI accumulated adopted Analysis ARIMA Asymptomatic Beijing China Combined confirmed cases coronavirus disease country COVID-19 COVID-19 epidemic cumulative death disease Epidemic expected Government Guangzhou Hospitalization interfere Intervention mathematical measure medical need Migration modeling number of infected other disease outbreak Patient predicted professionals recovered Result SEIR Shanghai the epidemic virus carrier was used would increase Wuhan [DOI] 10.1186/s41256-020-00145-4 PMC 바로가기 [Article Type] Research
Diagnostic value and key features of computed tomography in Coronavirus Disease 2019Review Published on 2020-04-232022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome caused change Characteristics China Clinical diagnosis Clinical practice Clinicians Computed tomography consolidation coronavirus Coronavirus disease 2019 Course COVID-19 CT finding CT findings Diagnosis diagnosis and monitoring distribution Evidence feature Features ground-glass opacity help Infection Lungs other disease outbreak patients with COVID-19 provide radiological examination SARS-CoV-2 the disease treatment effect Typical Wuhan [DOI] 10.1080/22221751.2020.1750307 PMC 바로가기 [Article Type] Review
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infectionArticle Published on 2019-12-182022-10-29 Journal: Nature Communications [Category] Coronavirus, MERS, [키워드] affecting AKT1 antiviral drug antivirals attenuate autophagic flux autophagy BECN1 block cellular conditions decrease Degradation E3 ligase ENhance Infection Lysosomes Macroautophagy MERS coronavirus MERS-CoV Middle East other disease pharmacological PHLPP Phosphorylation proteasomal degradation Protein reduce reduced regulated Replication respiratory syndrome coronavirus responsible resulting Skp2 Ubiquitin ligases virus infection [DOI] 10.1038/s41467-019-13659-4 PMC 바로가기 [Article Type] Article