Dynamic and Combinatorial Landscape of Histone Modifications during the Intraerythrocytic Developmental Cycle of the Malaria ParasiteArticle Published on 2016-08-052024-08-27 Journal: Journal of Proteome Research [Category] 말라리아, [키워드] cell cycle epigenetics Histones label-free quantification malaria multiple reaction monitoring parasite post-translational modifications Tandem mass spectrometry
Phylogeographic Evidence for 2 Genetically Distinct Zoonotic Plasmodium knowlesi Parasites, Malaysia말레이시아의 유전적으로 구별되는 2종의 유전적으로 구별되는 인수공통원체 Plasmodium Knowlesi 기생충에 대한 계통학적 증거Article Published on 2016-08-012023-05-31 Journal: Emerging Infectious Diseases [Category] Fulltext, 말라리아, 조류인플루엔자, [키워드] biological evolution Cytochrome oxidase 1 genetic diversity Human macaque malaria Malaysia Malaysian Borneo parasite Peninsular Malaysia Plasmodium knowlesi Population genetics ribosomal RNA Simian Southeast Asia zoonoses [DOI] 10.3201/eid2208.151885 PMC 바로가기
Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity비복제 Toxoplasma gondii Uracil Auxotrophs에 의한 Rhoptry 및 Dense Granule Effector 단백질의 분비는 항종양 면역의 발달을 제어합니다Research Article Published on 2016-07-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogated activate activated acute infection Auxotroph auxotrophic mutants axis CD4 CD8 Cell Nucleus Cell signaling cellular signaling pathway cellular signaling pathways conjunction Control deleted Deletion dendritic cells Dense development effective effective therapy effector effector molecule effector molecules effector protein effector proteins function Granule GTPase GTPases Host host cell host cell nucleus host cell response Host immune response host immune responses host innate immunity host response host responses identify IFN-γ immune responses Immune suppression Immunity independent Infection interferon Invasion latent infection mammalian cell mechanism membrane mice mutant not affect nucleus ovarian cancer parasite pathway Pathways Protein required responses rhoptry Safe secreted secretion shown Signaling solid tumor solid tumors survival T cell T cells target therapeutic These data Toxoplasma gondii transcriptional Trigger Tumor tumor microenvironment tumors type I uracil vaccination vaccine strain virulence [DOI] 10.1371/journal.pgen.1006189 PMC 바로가기 [Article Type] Research Article
Major Parasitic Zoonoses Associated with Dogs and Cats in EuropeReview Published on 2016-07-012023-06-03 Journal: Journal of comparative pathology [Category] 조류인플루엔자, [키워드] companion animal Europe parasite zoonotic disease [DOI] 10.1016/j.jcpa.2015.10.179 [Article Type] Review
NF-YB Regulates Spermatogonial Stem Cell Self-Renewal and Proliferation in the Planarian Schmidtea mediterraneaNF-YB는 Planarian Schmidtea 지중해에서 정자 줄기 세포 자가 재생 및 증식을 조절합니다Research Article Published on 2016-06-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] balance carrier causative agent Cell cell population cell proliferation cells combating complex component conserved coordination developmental differentiation disease Disruption etiology Factor fecundity Gamete genetic information germ cell germ cells help homolog identification implication Implications infertility inhibited involved lead life maintenance male mechanism morbidity observation open organism Organisms parasite Pathogenesis Planarian proliferation Propagation reproductive required Schistosoma mansoni schistosome Schistosomiasis Sperm SSC STEM stem cell stem cells testes transcription factors Transmission tropical tropical disease Tumor tumorigenesis tumors [DOI] 10.1371/journal.pgen.1006109 PMC 바로가기 [Article Type] Research Article
A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive보존된 DNA 반복은 게놈 아카이브에서 트리파노소마 브루세이 표면 항원의 다양한 레퍼토리 선택을 촉진합니다Research Article Published on 2016-05-052022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated addition African African trypanosomiasis antigenic variation archive assumption bloodstream catastrophic Cell cell cycle Chromosomal translocation Chromosomal translocations chromosome chronic condition conserved demonstrated DNA DNA sequence Donor event expression gene conversion genetic change Genome genomic homolog homology Host Hypothesis identify implicated induce infect Infection iteration mammalian manipulation natural infection observation observé outcome parasite pathogen Pathogens promote Protein proximal Recombination recombination event reduction in Region Repeat repertoire required selected Selection sequence silent species Support surface Surface glycoprotein switching synthetic tested the cell These data transcribed translocation Trypanosoma Trypanosoma brucei Trypanosome trypanosomiasis Variant Surface Glycoprotein VSG [DOI] 10.1371/journal.pgen.1005994 PMC 바로가기 [Article Type] Research Article
Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug developmentArticle Published on 2015-11-282024-08-27 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] ACT, Artemisinin-based Combination Therapies CQ, Chloroquine Drug development EC50, concentration causing 50% of maximal effect ENT, equilibrative nucleoside transporter EV, empty vector hENT1, human ENT type 1. HTS, high throughput screen IC50, concentration causing 50% inhibition malaria NBMPR, 4-nitrobenzylthioinosine Nucleoside/nucleobase transport parasite PfENT1, P. falciparum ENT type 1 Plasmodium vivax purines PvENT1, P. vivax ENT type 1 SDM, synthetic defined media Single-nucleotide polymorphism (SNP) SNP, single nucleotide polymorphism transporter WHO, World Health Organization WT, wild type
Applying chemical genetic tools to the study of phospho-signalling pathways in malaria parasitesarticle Published on 2015-10-312024-09-01 Journal: Cities [Category] 말라리아, [키워드] Chemical genetics malaria mass spectrometry parasite phosphoproteome Phosphorylation Plasmodium protein kinase proteome [Article Type] article
Plasmodium infections and fluctuating asymmetry among children and teenagers from Senegalarticle Published on 2015-06-302024-09-01 Journal: Infection, Genetics and Evolution [Category] 말라리아, [키워드] Fluctuating asymmetry Human Infection malaria parasite Plasmodium [Article Type] article
The merozoite surface protein 1 complex is a platform for binding to human erythrocytes by Plasmodium falciparumArticle Published on 2014-09-122024-08-29 Journal: Brain stimulation [Category] 말라리아, [키워드] Cell invasion complex Falciparum Infection malaria Merozoite parasite Plasmodium protein complex