Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS데드 스페이스 추정치는 COVID-19 ARDS의 28일 사망률과 독립적으로 연관되지 않을 수 있습니다.Observational Study Published on 2021-05-172022-09-11 Journal: Critical Care [Category] 바이오마커, 임상, [키워드] 28-day mortality acute respiratory distress acute respiratory distress syndrome added Analysis ARDS baseline case sery Comorbidity consecutive patient consecutive patients Course COVID-19 dead Dead space dead space ventilation determine direct method eligible end-tidal estimate estimation fraction ICU impairment increase in increased risk information intensive care unit invasive ventilation marker mechanical ventilation Mortality multicenter National Netherlands non-survivor observational study outbreak Participation Patient prognostic Prognostic value Prognostication quantification Registered Respiratory dead space respiratory distress Respiratory distress syndrome Result retrospective risk secondary severity shown significantly significantly higher supplementary material surrogate markers survivor syndrome the dead Trial registration Ventilation ventilatory Ventilatory ratio [DOI] 10.1186/s13054-021-03570-0 PMC 바로가기 [Article Type] Observational Study
Assessment of a Crowdsourcing Open Call for Approaches to University Community Engagement and Strategic Planning During COVID-19Research Published on 2021-05-142022-10-29 Journal: JAMA Network Open [Category] Coronavirus, SARS, [키워드] Analysis analyzed approach assessment Chapel collected Community COVID-19 COVID-19 pandemic demographic develop Digital Engagement equity evaluate evaluated exacerbated feasibility feasible finding Health Hill implementation Importance IMPROVE indicated individual individuals lack limitation measure media mental health North objective offered pandemic participant Participants Participation physical Planning Point Population Relevance resource Result Safe setting solution submission Support university were used women [DOI] 10.1001/jamanetworkopen.2021.10090 PMC 바로가기 [Article Type] Research
Attitudes toward Vaccination against COVID-19 in Poland. A Longitudinal Study Performed before and Two Months after the Commencement of the Population Vaccination Programme in PolandArticle Published on 2021-05-132022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] analysed Attitude attitudes toward vaccination changes in chronic disease collected Complication COVID-19 COVID-19 vaccination demonstrated effective Effectiveness Efficiency first stage Healthcare systems healthcare worker Immunity indicate information Internet involved knowledge longitudinal Month pandemic participant Participation Poland Population Prophylactic Public question questionnaire Research response significantly slight increase Sociodemographic Stage stage I stages the WHO vaccinated against COVID-19 vaccination vaccination against COVID-19 Vaccine virus was used women [DOI] 10.3390/vaccines9050503 PMC 바로가기 [Article Type] Article
Clinical profile and factors associated with COVID-19 in Yaounde, Cameroon: A prospective cohort studyResearch Article Published on 2021-05-122022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] age Analysis chain clinical clinical feature Clinical sign Comorbidity confirmed case confirmed cases COVID-19 COVID-19 case COVID-19 pandemic COVID-19 severity demographic diabete diagnosis of COVID-19 disease distress Dyspnoea Factor fatality Fatality rate fatigue feature finding Gender group HIV infection hypertension information invasive ventilation Lung disease male male group material Mild moderate MOST Participation Patient PCR Pneumonia predict predicted Predictive predominant profile prospective cohort study public health ranged Ratio reaction risk Severe case severe COVID-19 severity significantly symptomatic was performed with COVID-19 [DOI] 10.1371/journal.pone.0251504 PMC 바로가기 [Article Type] Research Article
Intestinal Microbiota—A Promising Target for Antiviral Therapy?장내 미생물군—항바이러스 치료의 유망한 표적인가?Review Published on 2021-05-122022-09-11 Journal: Frontiers in Immunology [Category] SARS, 치료제, [키워드] abundance Adaptive immune response Anti-viral immunity Antibiotics Antiviral Antiviral effect antiviral effects balance changed clinical trials component COVID-19 curative curative effects Effect facilitate gut microbiota immune responses Immunity inhibit inhibitory Interaction intestinal intestinal microbiota microbiota oral administration Participation Pathogens primary mechanism Probiotics Research SARS-CoV-2 shown target therapeutic strategy therapeutic target thought Viral viral infection viral infections viral invasion virus viruses [DOI] 10.3389/fimmu.2021.676232 PMC 바로가기 [Article Type] Review
Study protocol of the Edinburgh and Lothian Virus Intervention Study in Kids: a randomised controlled trial of hypertonic saline nose drops in children with upper respiratory tract infections (ELVIS Kids)어린이에 대한 에딘버러 및 로시안 바이러스 중재 연구의 연구 프로토콜: 상부 호흡기 감염이 있는 어린이의 고장성 식염수 점비제에 대한 무작위 대조 시험(ELVIS Kids)Article Published on 2021-05-052022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] 24 hour 24 hours 48 hour 48 hours age All participant All participants approved asked Asymptomatic board Care Child child health children chloride clinical Community community child health Complete Contact control arm Controlled trial determine Edinburgh Ethics events Health hypertonic hypertonic saline immunisation Infection Infectious disease Intervention intervention arm Local media nasal swab National Health Service neonatology nose drop nose drops nostril office Open-label paediatric infectious disease & Participation partnership peer-reviewed primary care protocol provided questionnaire randomised randomised controlled trial recruited recruitment registration number Research Research Ethics satisfaction questionnaire service Sodium chloride standard care Symptom symptomatic university upper respiratory tract upper respiratory tract infection URTI URTI symptom URTI symptoms Virology website West wheeze [DOI] 10.1136/bmjopen-2021-049964 PMC 바로가기 [Article Type] Article
Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk populationRandomized Controlled Trial Published on 2021-05-012022-10-04 Journal: BMC Geriatrics [Category] 임상, [키워드] addition Aged changes in chronic disease clinical trial Complete complex complications conducted Controlled trial coronavirus disease COVID-19 COVID-19 situation E-health Efficacy equipment Eurythmy therapy exercise Exercise intervention expected Falls feasibility group groups Healthcare provider healthy high risk high-risk population identify implementation individual individuals International interview involved limitation literature review lockdown management National outcomes pandemic participant Participation Patient performed physical randomised controlled trial researcher resolved resources Result risk social contact solution Study design study population subsequent Tai Chi Telemedicine Trial trial participant trials [DOI] 10.1186/s12877-021-02232-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk populationRandomized Controlled Trial Published on 2021-05-012022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] addition Aged changes in chronic disease clinical trial Complete complex complications conducted Controlled trial coronavirus disease COVID-19 COVID-19 situation E-health Efficacy equipment Eurythmy therapy exercise Exercise intervention expected Falls feasibility group groups Healthcare provider healthy high risk high-risk population identify implementation individual individuals International interview involved limitation literature review lockdown management National outcomes pandemic participant Participation Patient performed physical randomised controlled trial researcher resolved resources Result risk social contact solution Study design study population subsequent Tai Chi Telemedicine Trial trial participant trials [DOI] 10.1186/s12877-021-02232-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Acquired decrease of the C3b/C4b receptor (CR1, CD35) and increased C4d deposits on erythrocytes from ICU COVID-19 patientsICU COVID-19 환자의 C3b/C4b 수용체(CR1, CD35) 획득 감소 및 적혈구의 C4d 침착 증가Article Published on 2021-05-012022-09-11 Journal: Immunobiology [Category] SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Acquired Activation Activation factor assisted ventilation C3 C4 C4d capillary CD35 cell debris clearance Clinical severity coated complement Complement activation Course COVID-19 COVID-19 patient COVID-19 patients CR1 cumulative damage decrease disease endothelial erythrocyte erythrocytes Erythrocytes. France handling healthy individual healthy individuals highlight ICU immune complex immune pathophysiology individuals Inflammation innate immune response marker measurement mechanism observation organ Organ transplant parameter Participation pathophysiology Patient patients Protein receptor regulate Regulatory rejection reported SARS-CoV-2 SLE student t-test therapy transplant rejection Ventilation Virus spike were assessed [DOI] 10.1016/j.imbio.2021.152093 PMC 바로가기 [Article Type] Article
Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk populationRandomized Controlled Trial Published on 2021-05-012022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, SARS, [키워드] addition Aged changes in chronic disease clinical trial Complete complex complications conducted Controlled trial coronavirus disease COVID-19 COVID-19 situation E-health Efficacy equipment Eurythmy therapy exercise Exercise intervention expected Falls feasibility group groups Healthcare provider healthy high risk high-risk population identify implementation individual individuals International interview involved limitation literature review lockdown management National outcomes pandemic participant Participation Patient performed physical randomised controlled trial researcher resolved resources Result risk social contact solution Study design study population subsequent Tai Chi Telemedicine Trial trial participant trials [DOI] 10.1186/s12877-021-02232-8 PMC 바로가기 [Article Type] Randomized Controlled Trial