Low testosterone predicts hypoxemic respiratory insufficiency and mortality in patients with COVID-19 disease: another piece in the COVID puzzle낮은 테스토스테론은 COVID-19 질병 환자의 저산소성 호흡 부전 및 사망률을 예측합니다: COVID 퍼즐의 또 다른 조각Article Published on 2022-04-012022-09-11 Journal: Journal of Endocrinological Investigation [Category] 바이오마커, [키워드] 95% CI 95% confidence interval acute illness acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age association C-reactive protein clinical impact Comorbidities coronavirus coronavirus disease COVID COVID-19 described evaluate evaluated ferritin fraction Hospital stay Hospitalized hypogonadism hypoxemic in-hospital mortality Infection Inflammation inflammatory parameter inflammatory parameters interleukin-6 investigated IRCCS Italy Lactate lactate dehydrogenase male male subject male subjects Mortality mortality rate multivariable Odds ratio Older outcome oxygen P/F ratio PaO partial pressure patients with COVID-19 Pneumonia predict Prevalence Prospective Regression analyses respiratory respiratory insufficiency SARS-CoV-2 SARS-COV-2 infection serum severe acute respiratory syndrome Coronavirus significantly subject syndrome Testosterone thyroid function Ventilation [DOI] 10.1007/s40618-021-01700-7 PMC 바로가기 [Article Type] Article
Undetectable viral RNA in follicular fluid, cumulus cells, and endometrial tissue samples in SARS-CoV-2-positive womenSARS-CoV-2 양성 여성의 난포액, 난운 세포 및 자궁내막 조직 샘플에서 검출할 수 없는 바이러스 RNAObservational Study Published on 2022-04-012022-09-11 Journal: Fertility and sterility [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] 48 hours Adequate affecting analyzed ART assisted reproductive technology can not caution cells clinical Clinical outcome clinical outcomes conception counseling cumulus cells cycle Cycle threshold values developmental Embryo embryo transfer endometrium English fertilization follicular Follicular fluid hospital human embryo. in vitro In vitro fertilization infected with SARS-CoV-2 Inflammatory injection Intracytoplasmic sperm injection lesion observational study Oocyte outcome para parameter parameters Patient positive Primary outcome Prospective prospectivo registration number reproductive Reproductive technology Research Retrieval risk RT-PCR Sample SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 viral RNA secondary outcome single-center small sample size Spanish Tertiary threshold value tissue sample TRA transfer Trial registration undetectable Viral RNA women [DOI] 10.1016/j.fertnstert.2021.12.032 PMC 바로가기 [Article Type] Observational Study
Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection바이러스성 호흡기 감염에서 박테리아를 구별하기 위한 신속한 숙주 유전자 발현 검사의 전향적 검증Multicenter Study Published on 2022-04-012022-09-11 Journal: JAMA Network Open [Category] 유전자 메커니즘, 진단, [키워드] 95% CI absence acute COVID-19 acute respiratory illness age Analysis antibacterial therapy antibiotic ARI Asian Bacterial Bacterial infection black Care cause Characteristics children clinical clinically Cohort Concordance diagnostic Emergency Departments enrolled Enrollment entire cohort Ethnicity expression febrile female followed by group groups Hispanic Host host gene host gene expression host response IMPROVE individual IQR less likelihood male median age Messenger RNA multicenter Native Negative predictive value NPV offer outcome outcomes participant Participants pathogen Patient patients with ARI patients with COVID-19 performance Positive predictive value Predictive value primary analysis Probability procalcitonin Prospective quantified Rapid reported respiratory Respiratory illness resulting sensitivity specificity stratified Test the median validation Viral viral infection white with COVID-19 [DOI] 10.1001/jamanetworkopen.2022.7299 PMC 바로가기 [Article Type] Multicenter Study
[COVID-19 and change to home nursing care: Prospective study on 100 patients followed in CLCC]Observational Study Published on 2022-04-012022-10-04 Journal: Bulletin du cancer [Category] 임상, [키워드] asked Cancer Care Complete conducted Continuité des soins continuity Continuity of care COVID-19 COVID-19 epidemic determine English French Frequency home home care lockdown material measure Modification nous OMS palliative Palliative care Patient patients performance status performed Population Prospective Prospective Study reduction Soins à domicile Soins de support Soins palliatifs Support supportive care the ethics committee the patient vulnerable patients women [DOI] 10.1016/j.bulcan.2022.01.013 PMC 바로가기 [Article Type] Observational Study
Inactivated Whole-virus Vaccine Triggers Low Response Against SARS-CoV-2 Infection Among Renal Transplant Patients: Prospective Phase 4 Study Results비활성화된 전체 바이러스 백신은 신장 이식 환자에서 SARS-CoV-2 감염에 대한 낮은 반응을 유발합니다: 예상 4상 연구 결과Clinical Trial Published on 2022-04-012022-09-11 Journal: Transplantation [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, [키워드] A significant reduction acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adverse reaction Adverse reactions Against Analysis antibody Antibody Response Antibody responses clinical effectiveness Cohort CoronaVac coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death elicit first dose humoral Humoral response IgG antibodies IgG antibody inactivated incidence of COVID-19 increase individual intramuscular dose kidney transplant recipients lack lethality rate lethality rates mRNA vaccine Neutralizing antibodies occurred Patient patients phase 4 proportion Prospective Prospective trial reactogenicity recipient recipients reduced reduction in remained reported respiratory response Result SARS-CoV-2 second dose Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus single-center solid-organ transplant Transplant transplantation Trigger vaccination vaccination schedule Vaccine [DOI] 10.1097/TP.0000000000004036 PMC 바로가기 [Article Type] Clinical Trial
Humoral response to SARS-CoV-2 infection among liver transplant recipients간 이식 환자의 SARS-CoV-2 감염에 대한 체액 반응Multicenter Study Published on 2022-04-012022-09-11 Journal: Gut [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, 치료법, [키워드] anti-S antibody antibody Antibody Response Antibody testing Antibody titre assigned B lymphocytes case-control study Cohort cohorts controls COVID-19 COVID-19 symptom COVID-19 symptoms criteria detectable expected functional humoral Humoral response immune immune response Immunosuppression Immunosuppressive agents interfere less liver liver transplant Liver transplantation majority mounted multicentre neutralising ability Neutralising activity no difference nucleocapsid protein Patient Prospective Protein recipient recipients required SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection Serologic response significantly lower subject Symptoms Testing the antibody response with COVID-19 [DOI] 10.1136/gutjnl-2021-326609 PMC 바로가기 [Article Type] Multicenter Study
Determinants of Immune Response to Anti-SARS-CoV-2 mRNA Vaccines in Kidney Transplant Recipients: A Prospective Cohort Study신장 이식 수혜자의 Anti-SARS-CoV-2 mRNA 백신에 대한 면역 반응의 결정 요인: 전향적 코호트 연구Article Published on 2022-04-012022-09-12 Journal: Transplantation [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 95% confidence interval acute respiratory syndrome affecting analyzed antibody contrary coronavirus coronavirus disease Cutoff depleting determinant Effectiveness epitope evaluated exhibited Factor humoral immune response independent infected with SARS-CoV-2 interferon gamma kidney transplant recipient mRNA mRNA vaccines mycophenolate Odds ratio Patient Prospective prospective cohort study response S1 and S2 SARS-CoV-2 sensitivity Seroconversion shown significantly more Specific T-cell response specificity Spike protein subset subunit sustained tested the interferon therapy Transplant vaccination Vaccine [DOI] 10.1097/TP.0000000000004044 PMC 바로가기 [Article Type] Article
Spread of hypervirulent multidrug-resistant ST147 Klebsiella pneumoniae in patients with severe COVID-19: an observational study from Italy, 2020-21Observational Study Published on 2022-03-312022-10-05 Journal: Journal of Antimicrobial Chemotherapy [Category] Coronavirus, 임상, [키워드] Bloodstream infections capsular carried chromosome clinical collected Combination Complete COVID-19 COVID-19 patient COVID-19 patients Diagnosis enhancer ESBL genes encoding high mortality Illumina Miseq Infection infection control isolate Italy Klebsiella pneumoniae majority measure Mortality multidrug-resistant outbreak outcome Patient phenotype Plasmid Prospective rectal reported resistance genes Sequencing strain string test Surveillance susceptibility treated university urinary tract infections Urine Ventilator-associated pneumonia was determined was performed whole genome [DOI] 10.1093/jac/dkab495 PMC 바로가기 [Article Type] Observational Study
Association of the Intermountain Risk Score with major adverse health events in patients positive for COVID-19: an observational evaluation of a US cohortObservational Study Published on 2022-03-242022-10-04 Journal: BMJ Open [Category] SARS, 임상, [키워드] 95% CI BMP calculated Care CBC Cohort Comorbidities Comorbidity complete blood count composed composite endpoint conducted COVID-19 COVID-19 diagnosis COVID-19 hospitalisation diagnosed died Epidemiology evaluated event group Health high risk hospitalisation hospitalised hypothesised identify laboratory result Laboratory results Mild moderate Mortality multivariable analyses Observational cohort study outcome parameter Patient patients positive predict predicted Predictive Preventive medicine Primary outcome Prospective public health risk RNA SARS-CoV-2 SARS-COV-2 infection score secondary outcome shown subject substantial risk tested Utah Variation Weighting [DOI] 10.1136/bmjopen-2021-053864 PMC 바로가기 [Article Type] Observational Study
Can Teledentistry Replace Conventional Clinical Follow-Up Care for Minor Dental Surgery? A Prospective Randomized Clinical TrialRandomized Controlled Trial Published on 2022-03-152022-10-05 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] assigned average both groups Can Care clinical complications Conventional COVID-19 pandemic dental Follow-up Frequency healthcare Healthcare professional implementation Local minor offered oral health oral surgery outcomes Patient Prospective questionnaire Questionnaires randomized trial Randomly Satisfaction significant increase statistically significant difference subject Symptom Symptoms Teledentistry Telemedicine Travel was performed [DOI] 10.3390/ijerph19063444 PMC 바로가기 [Article Type] Randomized Controlled Trial