Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa파seudomonas aeruginosa의 M18 아미노펩타이드 분해효소의 금속 선호에 대한 구조적 및 운동학적 기초journal-article Published on 2014-04-012024-08-04 Journal: Biochemical and Biophysical Research Communications [Category] 폐렴구균 감염증, [키워드] Aspartyl aminopeptidase enzyme kinetics M18 family Pseudomonas aeruginosa Tetrahedral aminopeptidase. [DOI] 10.1016/j.bbrc.2014.03.109 [Article Type] journal-article
Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection작은 분자에 의한 숙주 면역 방어의 자극은 세균 감염으로부터 C. elegans를 보호합니다Research Article Published on 2012-06-142022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect Analysis antibiotic Antibiotics ATF-7 Author Bacterial Bacterial infection Bacterial infections bacterial pathogen Bacterial pathogens Caenorhabditis elegan Caenorhabditis elegans cellular processe cellular processes Compound conserved effector molecule Efficacy elegan expression Gene Genes growth Host immune response host immunity identify immune immune regulators immunostimulatory Infection Interaction low molecular weight mechanism mechanism of action mode molecule molecules mutants nematode offer Pathogens pathway promote PROTECT Pseudomonas aeruginosa required small molecule Small molecules stimulate Stimulation tested therapy These data Transcription transcription factor Transcriptome Treatment variety [DOI] 10.1371/journal.pgen.1002733 PMC 바로가기 [Article Type] Research Article
A Decline in p38 MAPK Signaling Underlies Immunosenescence in Caenorhabditis elegansCaenorhabditis elegans에서 p38 MAPK 신호 전달의 감소는 면역 노화의 기초가 됩니다Research Article Published on 2011-05-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addressed age aging amplify Author Bacteria Bacterial Bacterial infection Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans change conserved cycle death Decline declines Defense defined Deterioration elegan examined exhibit Genetic Host host defense human pathogen humans immune function immunosenescence impair implicated increase in Infection innate immune Innate immunity intestinal intestinal tissue involved leads MAPK mice mitogen mitogen-activated protein kinase molecular basis molecular mechanism motion pathogen pathway phenomenon PMK-1 proliferation promote Protein protein kinase Pseudomonas aeruginosa regulate signaling pathway susceptibility tissue damage turn [DOI] 10.1371/journal.pgen.1002082 PMC 바로가기 [Article Type] Research Article
Factors Influencing Fluoroquinolone Resistance플루오로퀴놀론 내성에 영향을 미치는 요인Letter to the Editor Published on 2003-12-012024-08-10 Journal: Emerging Infectious Diseases [Category] 폐렴구균 감염증, [키워드] fluoroquinolones Mutation Pseudomonas aeruginosa resistance Streptococcus pneumoniae [DOI] 10.3201/eid0912.03-168 PMC 바로가기 [Article Type] Letter to the Editor