Spectrum and Clinical Characteristics of Symptomatic and Asymptomatic Coronavirus Disease 2019 (COVID-19) With and Without PneumoniaMedicine Published on 2021-04-012022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome applied Asymptomatic Asymptomatic COVID-19 caused Characteristics China clinical Clinical characteristics coronavirus Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 group COVID-19 patient Covid-19 subgroup database defined evaluated extracorporeal membrane oxygenation four groups global pandemic groups hospital Hospitalization Hospitalized in viral information Invasive mechanical ventilation Laboratory mechanical ventilation medical resource no difference Non-invasive oropharyngeal swab Pneumonia Prognosis radiologic renal replacement therapy Spectrum stratified Symptom symptomatic symptomatic and asymptomatic Symptoms Viral load viral shedding [DOI] 10.3389/fmed.2021.645651 PMC 바로가기 [Article Type] Medicine
Severe acute kidney injury in critically ill COVID-19 patientsObservational Study Published on 2021-04-012022-10-05 Journal: Journal of Nephrology [Category] SARS, 임상, [키워드] Acute kidney injury Admission AKI assessment Barcelona Characteristics correlation COVID-19 COVID-19 patient Critically ill Diagnosis Factor failure high mortality Hospital stay ICU ICU Patients independent predictor inflammation marker intensive care kidney Kidney injury liver median moderate-severe Mortality outcome Patient patients Prevalence progression Prospective reduced renal replacement therapy replacement required RRT SOFA Spain study period the patient therapy use of corticosteroid [DOI] 10.1007/s40620-020-00918-7 PMC 바로가기 [Article Type] Observational Study
COVID-19 and Diabetic Ketoacidosis: Report of Eight CasesEndocrinology/Diabetes/Metabolism Published on 2021-03-312022-10-31 Journal: Cureus [Category] COVID-19, [키워드] age AKI All the patient case sery Clinical characteristics Clinical outcome collected COVID 19 COVID-19 COVID-19 infection Diabetes Mellitus Diabetic diabetic hyperglycemic hyperosmolar syndrome diabetic ketoacidosis (dka) diagnosed eight electronic medical record female FIVE Glucose glycosylated hemoglobin hospitalized COVID-19 patient initial insulin intravenous fluid ketotic hyperglycemia Kidney injury Laboratory male mechanical ventilation median age moderate Mortality Nasopharyngeal swab New outcome Patient patients patients died polymerase chain protocol renal replacement therapy report required Result reverse transcription risk factor RT-PCR sar-cov 2 infection Seven Sex standard treatment the patient type 2 diabete type i diabetes mellitus types 2 diabetes USA [DOI] 10.7759/cureus.14223 PMC 바로가기 [Article Type] Endocrinology/Diabetes/Metabolism
The impact of viremia on organ failure, biomarkers and mortality in a Swedish cohort of critically ill COVID-19 patients심각한 COVID-19 환자의 스웨덴 코호트에서 장기 부전, 바이오마커 및 사망률에 대한 바이러스혈증의 영향Observational Study Published on 2021-03-302022-09-10 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료기술, 치료법, [키워드] Acute inflammation admitted to ICU age association Biomarker blood stream Cohort Consent contribute coronavirus disease Coronavirus disease 2019 Corticosteroid corticosteroid treatment COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients death defined had more hypertension ICU admission ICU patient ICU Patients independent Inflammation Innate immunity Mortality Organ failure Patient PCR plasma renal replacement therapy replacement therapy RNA copies RNA copy SARS-CoV-2 SARS-CoV-2 RNA copies SARS-CoV-2 RNA copy SARS-CoV2 Spread suggested Swedish Trial registration Ventilated viral infection Viremia virus with COVID-19 [DOI] 10.1038/s41598-021-86500-y PMC 바로가기 [Article Type] Observational Study
Predicting the outcome of COVID-19 infection in kidney transplant recipientsResearch Article Published on 2021-03-192022-10-28 Journal: BMC Nephrology [Category] COVID-19, SARS, [키워드] Admission age AKI ALT Analysis analyzed AST Characteristics Clinical findings Clinical outcome Cohort collected conducted COVID-19 COVID-19 infection CRP demographic demographic characteristics died ferritin Follow-up ICU ICU admission in-hospital mortality independent risk factor independent variable initial Invasive mechanical ventilation ischemic heart disease Kidney injury kidney transplant recipient Kidney transplantation laboratory parameter LDH Lymphocyte count lymphopenia Mortality multicenter multivariable analysis nine Older outcome over Patient patients patients hospitalized Primary outcome reached recipient registry renal replacement therapy required Result Retrospective study RRT secondary outcome serum albumin serum creatinine Serum ferritin severe COVID-19 significantly the patient treatment strategy Turkey with COVID-19 [DOI] 10.1186/s12882-021-02299-w PMC 바로가기 [Article Type] Research Article
Severe liver dysfunction complicating course of COVID-19 in the critically ill: multifactorial cause or direct viral effect?Research Published on 2021-03-152022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] 95% CI admitted to ICU age analyzed caused Characteristics Cholestatic liver disease clinical Clinical characteristics Comorbidity confounders contribute coronavirus disease Course COVID-19 Critically ill Critically ill patient defined ECMO evaluated Gender had more Health high mortality Hypoxic liver injury ICU in both groups jaundice Laboratory liver dysfunction Liver injury mechanical ventilation Mortality multifactorial Occurrence outcome overlapped pandemic Patient Presence renal replacement therapy reported required Result SARS-CoV-2 severe respiratory failure severity severity of illness significantly higher supplementary material therapy ULN university hospital Viremia with COVID-19 [DOI] 10.1186/s13613-021-00835-3 PMC 바로가기 [Article Type] Research
Clinical characteristics and outcome of critically ill COVID-19 patients with acute kidney injury: a single centre cohort studyResearch Article Published on 2021-03-152022-10-28 Journal: BMC Nephrology [Category] COVID-19, [키워드] acute kidney Acute kidney injury Admission AKI APACHE II baseline Characteristics clinical cohort study Complete conducted COVID-19 COVID-19 patient criteria Critical Critically ill Critically ill patient defined Diabetes Mellitus Evidence hospital hypoxic respiratory failure ICU Immunosuppression Improving incidence increased mortality intensive care invasive mechanical Invasive mechanical ventilation KDIGO Kidney injury lymphopenia medical record morbidity and mortality Mortality multifactorial noninvasive outcome outcome analysis outcomes pathophysiology Patient patients patients with AKI presenting renal renal function renal replacement therapy replacement Result risk factor RRT SARS-COV-2 infection severity significantly SOFA scores Stage stage III supplementary material survived vasopressor support ventilatory support with COVID-19 [DOI] 10.1186/s12882-021-02296-z PMC 바로가기 [Article Type] Research Article
Time on previous renal replacement therapy is associated with worse outcomes of COVID-19 in a regional cohort of kidney transplant and dialysis patientsObservational Study Published on 2021-03-122022-10-05 Journal: Medicine [Category] SARS, 임상, [키워드] acute respiratory distress adverse outcome affected Analysis ARDS association Asymptomatic chronic Cohort cohort analysis cohorts coronavirus correlated COVID-19 COVID-19-associated ARDS death defined dialysis exhibited Germany Hemodialysis increased risk Interaction kidney transplant Logistic regression analysis majority Mortality multivariate observation outbreak outcome Patient patients proportion recipient remained renal renal replacement therapy retrospective risk factor robust RRT SARS-CoV-2 significantly survival syndrome time with COVID-19 [DOI] 10.1097/MD.0000000000024893 PMC 바로가기 [Article Type] Observational Study
Interventions for treatment of COVID-19: Second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)COVID-19 치료를 위한 중재: 메타 분석 및 시험 순차 분석이 포함된 살아있는 체계적인 검토의 두 번째 판(The LIVING 프로젝트)Meta-Analysis Published on 2021-03-112022-08-13 Journal: PLoS ONE [Category] Biochemistry, SARS, 임상, 진단, 치료제, [키워드] 95% CI 95% confidence interval adjusted Admission aggregate data meta-analyses all age group all age groups all-cause mortality Analysis boundary bromhexine caused certainty certainty of evidence Clinical research Clinical significance Cochrane guidelines comparison Comparisons Corticosteroid Corticosteroids COVID-19 database Effect Effects eight events Evidence evidence of Families FIVE Fixed-effect meta-analysis futility GRADE high risk Hydroxychloroquine Immunoglobulin indicate indication indications individual patient data meta-analyses individuals information intensive care Intervention effects intravenous Intravenous immunoglobulin lack life Lopinavir Lopinavir-ritonavir mechanical ventilation meta-analyses Meta-analysis moderate Network meta-analysis no evidence of non-serious adverse non-serious adverse events on mechanical ventilation outcome outcomes participant Participants patient data performed Primary outcomes PRISMA Quality of life random error random errors random-effects meta-analyses randomized clinical trial randomized clinical trials rapidly spreading disease reached reduce reduced Remdesivir renal replacement therapy replacement therapy required Research risk risk of death risk ratio risks of bia Ritonavir searched second secondary Secondary outcomes sequential analysis Serious Adverse Event Serious Adverse Events single trial standard care statistically significant systematic review threshold Tocilizumab Treatment treatment for COVID-19 treatment intervention treatments of COVID-19 Trial Trial methodology trial sequential analyses trial sequential analysis website with COVID-19 [DOI] 10.1371/journal.pone.0248132 PMC 바로가기 [Article Type] Meta-Analysis
Optimizing Management to Reduce the Mortality of COVID-19: Experience From a Designated Hospital for Severely and Critically Ill Patients in ChinaMedicine Published on 2021-03-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress analyzed anticoagulation anticoagulation treatment antiviral drug ARDS branch China Clinical features Comprehensive coronavirus disease correlation COVID-19 COVID-19 patient Critical Critically ill Critically ill patient CRRT cut-off value Cytokines effective ESR experience Fluid management glucocorticoid IL-6 IL-8 Ill Intervention intubated patients intubation Invasive mechanical ventilation laboratory data management moderate Mortality organ function PaO Patient patients procalcitonin reached reduce mortality reducing mortality renal replacement therapy retrospective Safe Serum ferritin severely and critically ill shown significantly higher single-center study Support survival syndrome therapy TNF-α Tongji Hospital Treatment treatment for COVID-19 treatment strategy Vaccine Valley ventilatory support [DOI] 10.3389/fmed.2021.582764 PMC 바로가기 [Article Type] Medicine