COVID-19 vaccine acceptance and its determinants: A cross-sectional study among the socioeconomically disadvantaged communities living in Delhi, IndiaResearch article Published on 2022-08-012022-10-05 Journal: Vaccine: X [Category] 신약개발, [키워드] acute respiratory syndrome analysed Behavioural research carried Clusters collected Community conducted Coronavirus-2 COVID-19 COVID-19 vaccine cross-sectional cross-sectional survey effort examined Factor group Health Health beliefs identify Immunity India Logistic regression Older age predictor PROTECT questionnaire Randomly Regression Result SARS-CoV-2 selected Self-efficacy severity severity of COVID-19 socio-demographic susceptibility the SARS-CoV-2 the vaccine Urban communities Vaccine Vaccine acceptance Vaccine hesitancy variables [DOI] 10.1016/j.jvacx.2022.100171 [Article Type] Research article
Differential susceptibility to SARS-CoV-2 in the normal nasal mucosa and in chronic sinusitis정상 비점막 및 만성 부비동염에서 SARS-CoV-2에 대한 감수성 감수성Article Published on 2022-08-012022-09-11 Journal: European Journal of Immunology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACE2 ACE2-expressing cell ACE2-expressing cells acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral immune response association Brain chronic Chronic rhinosinusitis close monitoring coronavirus CRS Culture deficiency disease eosinophils Eosinophils Human nasal mucosa Evidence gene expression difference gene expression differences high risk Human increase in individuals Infection investigated lung mechanism nasal nasal mucosa other organ other organs Patient progression reservoir respiratory tract rhinosinusitis SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Subtypes suggested susceptibility susceptible tissue tissue culture Transmission viral infection viral replication [DOI] 10.1002/eji.202249805 PMC 바로가기 [Article Type] Article
Vitamin C and its therapeutic potential in the management of COVID19Review Published on 2022-08-012023-07-10 Journal: Clinical nutrition ESPEN [Category] COVID19(2023년), [키워드] COVID19 nutrition Oxidative radicals susceptibility therapeutic Vitamin C [DOI] 10.1016/j.clnesp.2022.05.026 PMC 바로가기 [Article Type] Review
Differential Leukocyte Expression of IFITM1 and IFITM3 in Patients with Severe Pandemic Influenza A(H1N1) and COVID-19중증 유행성 인플루엔자 A(H1N1) 및 COVID-19 환자에서 IFITM1 및 IFITM3의 차등 백혈구 발현Article Published on 2022-08-012022-09-11 Journal: Journal of interferon & cytokine research : the of [Category] 바이오마커, 신종인플루엔자, [키워드] addressed characteristic Clinical characteristics Clinical outcome clinical outcomes Cohort Comparisons coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 disease disease susceptibility downregulation Endosomes evaluated Evidence expression healthy control healthy controls High-dose humans IFITM IFITM1 IFITM3 individual Infection Influenza influenza A influenza A(H1N1) leukocyte leukocytes lung Lungs membrane fusion mice Mortality mRNA expression murine model nucleotide outcome outcomes pandemic pandemic influenza participant Patient Pneumonia Protective Protein respiratory respiratory infections Single nucleotide polymorphism single nucleotide polymorphisms susceptibility transmembrane underlying disease Viral viral respiratory infection viral respiratory infections virus viruses [DOI] 10.1089/jir.2022.0036 PMC 바로가기 [Article Type] Article
Nonproductive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immune responsesSARS-CoV-2에 대한 PBMC의 비생산적 노출은 세포 고유의 타고난 면역 반응을 유도합니다Article Published on 2022-08-012022-09-11 Journal: Molecular Systems Biology [Category] SARS, 치료기술, [키워드] absence ACE2 receptor analyzed baseline bystander cell bystander cells Cell COVID-19 Culture Cytokines detectable Ex vivo experiment exposure to expression expression profile expression profiles healthy donor healthy donors human PBMC immune responses in vivo induce infected cell Infection innate immune response Interaction interferon interferon-stimulated gene interferon-stimulated genes interferon-stimulated genes. Invasion ISG ISGs Mild monocyte Monocytes mounted Particle Patient PBMC PBMCs physical proinflammatory cytokines respiratory tract response RT-PCR SARS-CoV SARS-CoV-2 severe COVID-19 Single-cell RNA sequencing STAT stimulate susceptibility triggered virus particle virus particles [DOI] 10.15252/msb.202210961 PMC 바로가기 [Article Type] Article
The genetic and evolutionary determinants of COVID-19 susceptibilityCOVID-19 감수성의 유전적 및 진화적 결정 요인Review Published on 2022-08-012022-09-11 Journal: European Journal of Human Genetics [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] admixture applied approach archaic humans cellular contribute Course COVID-19 COVID-19 illness COVID-19 susceptibility determinant disease disease susceptibility Diseases Ethnic groups event explain facilitated Factor Genetic Genetic predisposition Human genetics humans immunological immunological mechanism individual Infection infectious agents Infectious disease Infectious diseases knowledge molecular outbreak outcome Pandemics Pathogens Perspective recent finding recent findings reported SARS-COV-2 infection severity severity of COVID-19 susceptibility threat Threats Variability [DOI] 10.1038/s41431-022-01141-7 PMC 바로가기 [Article Type] Review
Epigenetic mechanisms regulate sex-specific bias in disease manifestations후성 유전적 메커니즘은 질병 발현에서 성별에 따른 편향을 조절합니다Review Published on 2022-08-012022-09-11 Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] 유전자 메커니즘, [키워드] affecting Anatomy Autoimmune disorders Cancer change chromosome Clinical outcome clinical study COVID-19 COVID-19 infection differential expression disease disease manifestation disease onset Diseases Effect Epigenetic epigenetic modification epigenetics exhibit explained expression fibrosis Genes Genetic Genetic and epigenetic changes Hormones immune response immune responses immune system implicated inactivation infections input involved Liver fibrosis mechanism Neuropsychiatric Neuropsychiatric diseases progression recent regulate Respiratory disease respiratory diseases response to therapy responsible Sex Sex bias Sex chromosome sex hormone Sex hormones susceptibility therapeutic targets therapy underlying disease X chromosome X-inactivation X-linked X-linked gene X-linked genes. [DOI] 10.1007/s00109-022-02227-x PMC 바로가기 [Article Type] Review
ABO blood group and link to COVID-19: A comprehensive review of the reported associations and their possible underlying mechanismsABO 혈액형 및 COVID-19와의 연관성: 보고된 연관성 및 가능한 기본 메커니즘에 대한 포괄적인 검토Review Published on 2022-08-012022-09-11 Journal: Microbial pathogenesis [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ABO ABO antibodies ABO blood Group system ABO blood type ABO blood types Affect antibodies Antigen association associations Blood Blood Group blood group system blood type cells COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients COVID-19 severity described Disease progression disease severity disease transmission Diseases explain facilitate genetic association genetic associations glycobiology glycoprotein group higher risk Host hypothese implication Infectious diseases Interaction locus lower risk management mechanism Mortality natural history outcome outcomes progression protective effect protective factor reported risk risk factor risk of infection SARS-CoV-2 SARS-COV-2 infection severity Structure susceptibility the disease thromboembolic Thromboembolic event Thromboembolic events Transmission transmitted with COVID-19 [DOI] 10.1016/j.micpath.2022.105658 PMC 바로가기 [Article Type] Review
Host genetic basis of COVID-19: from methodologies to genesCOVID-19의 숙주 유전적 기반: 방법론에서 유전자까지Review Published on 2022-08-012022-09-11 Journal: European Journal of Human Genetics [Category] COVID19(2023년), SARS, 바이오마커, 변종, 유전자 메커니즘, 진단, 치료제, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age association burden Burden test caused CFTR clinical manifestation Clinical outcome Comorbidities condition Coronavirus-2 COVID-19 COVID-19 Host Genetics Initiative COVID-19 pandemic COVID-19 patient COVID-19 patients described diagnostics disease severity explain Genetic genetic marker genome-wide significant genomic genomic loci GWAS help Initially initiative International loci methodology Predictive model provided public health rare variant SARS-CoV-2 SARS-COV-2 infection SELP Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Sex susceptibility the disease Therapeutics TLR3 TLR7 TMPRSS2 treating COVID-19 vaccination [DOI] 10.1038/s41431-022-01121-x PMC 바로가기 [Article Type] Review
Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestriesOAS1 넌센스 매개 부패의 유전적 조절은 유럽 및 아프리카 혈통의 환자에서 COVID-19 입원과의 연관성을 뒷받침합니다Article Published on 2022-08-012022-09-11 Journal: Nature Genetics [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 임상, 치료기술, 치료법, [키워드] accelerate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 African allele Analysis Antiviral association Bioinformatic clearance clinical trial contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity decrease disease early treatment European exonic expression functional Genetic genetic regulation Haplotype Hospitalization Hospitalized in vitro study interferon interferons locus mitigate molecular mechanism molecular mechanisms OAS1 Patient Protein reduced Regulation risk SARS-CoV-2 SARS-CoV-2 clearance severe COVID-19 splicing susceptibility variant with COVID-19 [DOI] 10.1038/s41588-022-01113-z PMC 바로가기 [Article Type] Article