Does a humoral correlate of protection exist for SARS-CoV-2? A systematic reviewSARS-CoV-2에 대한 체액 보호 상관관계가 있습니까? 체계적인 검토Article Published on 2022-04-082022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% CI 95% confidence interval Alpha anti-S antibody antibody levels B.1.1.7 binding antibody Biosis Breakthrough infection contribute convalescent correlation COVID-19 decrease Evidence examined global health humoral Humoral immunity immune component immunological incidence individual level Infection levels of antibodies marker Measures NIH occur pandemic performed Policy Quantitative Re-infection reported risk risk of infection SARS-CoV-2 searched systematic review the mean variant variants variants of concern Viral Viral load [DOI] 10.1371/journal.pone.0266852 PMC 바로가기 [Article Type] Article
Retinal Findings of Hospitalized Neonates Recovered from COVID-19 Infection: A Prospective, Observational, Descriptive StudyObservational Study Published on 2022-04-052022-10-04 Journal: Journal of tropical pediatrics [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory syndrome age alteration caused change Complication coronavirus Coronavirus disease 2019 COVID-19 COVID-19 infection duration of hospitalization Effect evaluated female Hospitalization indirect ophthalmoscopy initial male multiple tissue Neonatal Neonate Neonates ocular organs Patient performed Prospective recovered reported Retina retinal damage Retinal Finding retinal findings. the mean [DOI] 10.1093/tropej/fmac036 PMC 바로가기 [Article Type] Observational Study
Patients diagnosed with COVID-19 and treated with anakinra: a real-world study in the USAObservational Study Published on 2022-04-042022-10-05 Journal: Clinical and experimental immunology [Category] 임상, [키워드] Admission age Anakinra Analysis Antibiotics Clinical practice condition coronavirus disease Corticosteroids COVID-19 database database studies diagnosed diagnosed with COVID-19 died discharged Evidence finding hospital Hospital admission hyperinflammation ICU ICU admission intensive care interleukin (IL)-1 interleukin-1 receptor antagonist protein male mechanical ventilation Mortality Myocardial infarction Patient Real-world evidence receiving receptor renal required retrospective significantly higher significantly lower significantly shorter Standard deviation the mean treated Treatment USA [DOI] 10.1093/cei/uxab024 PMC 바로가기 [Article Type] Observational Study
Comparison of different sequencing techniques for identification of SARS-CoV-2 variants of concern with multiplex real-time PCR다중 실시간 PCR과 관련된 SARS-CoV-2 변이체 식별을 위한 다양한 시퀀싱 기술 비교Article Published on 2022-04-042022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Accuracy Alpha ambiguous base ambiguous bases assigned averaged correlated correlation Cost effectiveness country Coverage delta variant Delta variants detect error rate evade Illumina Immunity INDEL indels infections less Lineage multiplex nucleotide ONT Oxford Nanopore Technologies Oxford Nanopore Technology PCR PCR assay PHRED platform Probability real time real time PCR Real-time PCR real-time PCR assay resource SARS-CoV-2 variant SARS-CoV-2 variants sensitivity sequence sequenced Sequencing sequencing technology significantly Single nucleotide polymorphism single nucleotide variation single nucleotide variations SNP SNPs SNV the mean Transmissibility variant variants viruses [DOI] 10.1371/journal.pone.0265220 PMC 바로가기 [Article Type] Article
501Y.V2 spike protein resists the neutralizing antibody in atomistic simulations501Y.V2 스파이크 단백질은 원자 시뮬레이션에서 중화 항체에 저항합니다.Article Published on 2022-04-012022-09-11 Journal: Computational biology and chemistry [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 501Y.V2 antibody resistance atomic B.1.351 backbone binding caused CCS changed complex complexes COVID-19 pandemic COVID-19 vaccine design deaths distribution distributions experiment free energy free energy landscape indicated lead molecular molecular dynamics Mutation neutralizing antibody observation outbreak Protein reduced RMSD S protein SARS-CoV-2 SARS-CoV-2 variant significantly SMD SMD simulations spike Spike protein the mean variant wild-type [DOI] 10.1016/j.compbiolchem.2022.107636 PMC 바로가기 [Article Type] Article
Mindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical TrialRandomized Controlled Trial Published on 2022-04-012022-10-05 Journal: JAMA Internal Medicine [Category] 임상, [키워드] 95% CI age Asian assessment attrition baseline black caused chronic clinical clinics control condition COVID-19 pandemic defined demonstrated distress dose drug ecological Efficacy emotional enhancement enrolled evaluate Follow-up follow-up period functional greater group guideline Hispanic improvement index Intervention inventory IQR Latino medications Mindfulness-based misuse Odds ratio opioid outcome Pain participant Patient positive primary care Randomized randomized clinical trial receiving reduced reducing reduction reduction in reductions in secondary severity subscale score sustained Symptom the mean Therapies therapy Treatment Urine Utah white women [DOI] 10.1001/jamainternmed.2022.0033 PMC 바로가기 [Article Type] Randomized Controlled Trial
Overview of clinical outcome and therapeutic effectiveness of Favipiravir in patients with COVID-19 admitted to intensive care unit, Riyadh, Saudi Arabia사우디아라비아 리야드의 중환자실에 입원한 COVID-19 환자에 대한 Favipiravir의 임상 결과 및 치료 효과 개요Article Published on 2022-04-012022-09-11 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 임상, 진단, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome age analyzed antivirals approved ARDS BMI body mass body mass index Chloroquine Clinical outcome collected Comorbidities Comorbidity complications conducted control group Corticosteroid cough COVID-19 COVID-19 patient COVID-19 vaccine Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients cytokine Cytokine storm diabetes Diabetes Mellitus effective Effectiveness Efficacy Efficacy and safety enrolled enzyme Favipiravir Fever FIVE FVP group had no heart disease hospital hypertension ICU ICUs IMPROVE inhibit intensive care intensive care unit intensive care units ischemic heart disease Kingdom majority male management medications not effective other treatment other treatments overall mortality P-value pandemic Patient patients with COVID-19 Potential treatment Randomized Research respiratory distress Respiratory distress syndrome retrospective cohort study RNA RNA polymerase Saudi Arabia severe acute respiratory distress syndrome severe symptoms Shortness of breath statistically significant Symptom syndrome the cytokine storm the disease the mean therapeutic therapeutic efficacy therapy Tocilizumab two groups Viral viral infection viral infections viral replication with COVID-19 [DOI] 10.1016/j.jiph.2022.01.013 PMC 바로가기 [Article Type] Article
Can periodontal pockets and caries lesions act as reservoirs for coronavirus?치주낭과 충치 병변이 코로나바이러스의 저장소 역할을 할 수 있습니까?Article Published on 2022-04-012022-09-11 Journal: Molecular oral microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplify approach Asymptomatic Can caries Chain Reaction coronavirus cross-sectional cross-sectional study Ct value detect dissemination evaluate Genes infections information knowledge lesion lesions negative control participant Patient patients periodontal pocket polymerase chain polymerase chain reaction positive positive control positive COVID-19 real-time polymerase chain reaction reservoir reservoirs RT-PCR S gene SARS-CoV-2 SARS-CoV-2 detection sensitivity severe acute respiratory syndrome Coronavirus specificity symptomatic the mean the SARS-CoV-2 virus while [DOI] 10.1111/omi.12362 PMC 바로가기 [Article Type] Article
Assessment of the clinical and laboratorial profile of patients with obesity and asymptomatic COVID-19 undergoing bariatric surgery in Brazil브라질에서 비만 수술을 받은 무증상 COVID-19 환자의 임상 및 실험실 프로필 평가Article Published on 2022-04-012022-09-11 Journal: Obesity surgery [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age assessment Asymptomatic case Asymptomatic cases Asymptomatic COVID-19 Bariatric surgery BMI body mass body mass index Brazil C-reactive protein Case series Chain Reaction collected Complication Coronavirus-2 COVID19 demographic characteristics Dengue dengue virus diabete diabetes Diagnosis disease severity elapsed ferritin FIVE Hospital stay hypertension IgG incidence inflammatory markers Laboratory lymphocyte Lymphocytes marker Micronutrient micronutrients obesity operation Patient patients with obesity polymerase chain reaction positive positive RT-PCR postoperative Postoperative Complications Preoperative period previous diagnosis reported reported symptoms RT-PCR serology serum Serum level serum levels Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Sleeve Sleeve gastrectomy study period surgery tested the mean Vitamin D without symptom women Zinc [DOI] 10.1007/s11695-022-05891-7 PMC 바로가기 [Article Type] Article
High- Versus Low-Dose Dexamethasone for the Treatment of COVID-19-Related Acute Respiratory Distress Syndrome: A Multicenter, Randomized Open-Label Clinical TrialRandomized Controlled Trial Published on 2022-04-012022-10-04 Journal: Journal of Intensive Care Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome adjusted all-cause mortality analyzed ARDS ARMS caused clinical clinical trial coronavirus COVID-19 cumulative determine Dexamethasone dose enrolled Enrollment FIVE glycemic control group High-dose ICUs increase increase in infection rate intensive care unit intravenously low-dose mechanical ventilation median no difference Open-label outcome Patient patients with ARDS Primary outcome randomization Randomized Randomized controlled trial required respiratory secondary outcome significant difference significantly syndrome the mean Treatment Trial ventilator ventilator-free day VFD Viral pneumonia was increased weakness [DOI] 10.1177/08850666211066799 PMC 바로가기 [Article Type] Randomized Controlled Trial