Combined Use of Wells Scores and D-dimer Levels for the Diagnosis of Deep Vein Thrombosis and Pulmonary Embolism in COVID-19: A Retrospective Cohort StudyCardiology Published on 2021-09-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 95% CI absolute lymphocyte antiplatelet approach assessment benefit Blood urea nitrogen BMI body mass index Cancer Combined Complication coronavirus disease COVID-19 COVID-19 patient COVID-19 patients criteria D-dimer D-dimer level D-dimers deep Deep vein thrombosis diagnose diagnosing Diagnosis DVT Embolism failure Gender intubation Level male material Occurrence outcome Patient patients PE group Platelet positive Prevalence Primary outcome pulmonary Pulmonary embolism Result risk factor score secondary sensitivity severity SOFA specificity statistically significant systemic inflammation Systolic blood pressure Thromboembolism utility Vein VTE WBC well wells dvt score wells pe score [DOI] 10.7759/cureus.17687 PMC 바로가기 [Article Type] Cardiology
A Systematic Review and a Meta-Analysis Comparing Prophylactic and Therapeutic Low Molecular Weight Heparins for Mortality Reduction in 32,688 COVID-19 PatientsPharmacology Published on 2021-09-022022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 95% CI 95% confidence interval Activation all-cause mortality anticoagulation bleeding coronavirus disease COVID-19 COVID-19 patients dose effective Effectiveness Efficacy Endpoint evaluated hazard heparin heparin treatment heparins higher risk Hospital stay hospitalized COVID-19 patients increased risk LMWH LOS low molecular weight major bleeding Meta-analysis Mortality no difference Observational cohort study Patient patients performed potential therapy Prophylactic prophylactic dose Randomized controlled trial Ratio RCT reduced reducing mortality Registration reported review SARS-CoV2 secondary subgroup analysis systematic review therapeutic dose Thromboembolism Treatment unfractionated heparin was performed weight [DOI] 10.3389/fphar.2021.698008 PMC 바로가기 [Article Type] Pharmacology
COVID-19-related coagulopathy: A review of pathophysiology and pharmaceutical managementCOVID-19 관련 응고병증: 병태생리 및 약제 관리에 대한 검토Review Published on 2021-09-012022-09-12 Journal: Cell biology international [Category] SARS, 진단, [키워드] Activation alleviate coagulation dysfunction coagulation parameter Coagulopathy complement complications coronavirus coronavirus disease COVID-19 CoVs death disease severity early diagnosis Endothelial dysfunction etiology Factor Health help Hypoxemia Inflammation Injury Laboratory management Multiple nonpulmonary organ Novel coronavirus outbreak Pathogenesis pathophysiology patients Platelet Pneumonia primary symptom public health SARS-CoV-2 severe disease the disease therapeutic option Thromboembolism Treatment with COVID-19 World Health Organization Wuhan, China β-coronavirus [DOI] 10.1002/cbin.11623 PMC 바로가기 [Article Type] Review
Venous thromboembolism in patients with COVID-19 infection: risk factors, prevention, and managementReview article Published on 2021-09-012022-10-05 Journal: Seminars in vascular surgery [Category] SARS, 유전자 메커니즘, [키워드] Atypical complications COVID-19 infections COVID-19 patients event events hematologic incidence information knowledge management pathophysiology patients with COVID-19 Prophylaxis recommendations risk factor Risk factors therapeutic thromboembolic complication Thromboembolism venous venous thromboembolic [DOI] 10.1053/j.semvascsurg.2021.06.002 [Article Type] Review article
Decreased in-hospital mortality associated with aspirin administration in hospitalized patients due to severe COVID-19심각한 COVID-19로 인해 입원 환자에서 아스피린 투여와 관련된 병원 내 사망률 감소Article Published on 2021-09-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료제, [키워드] administration adverse effect adverse effects antiplatelet Aspirin association caused center Clinical data Cohort cohort study Comorbidities coronavirus disease Coronavirus disease 2019 COVID-19 COX Decreased demographics demonstrated Diagnosis Efficacy evaluate Hospitalization Hospitalized hospitalized patient hospitalized patients hypercoagulability Imam in-hospital mortality independent Iran Mortality mortality rate multivariate outcome Patient prevalent Primary outcome Randomized controlled trial receiving reduction in Result risk SARS coronaviruses severe COVID-19 significant decrease Tehran the patient therapy Thromboembolism thrombosis were recorded with COVID-19 [DOI] 10.1002/jmv.27053 PMC 바로가기 [Article Type] Article
Thrombotic and Hypercoagulability Complications of COVID-19: An UpdateReview Published on 2021-08-312022-10-29 Journal: Journal of Blood Medicine [Category] COVID-19, [키워드] affecting Anticoagulant China Clinical outcome Complication COVID-19 COVID-19 pandemic COVID-19 patient critically ill patients develop disease endothelial cell damage IMPROVE incidence include increase Inflammation management mechanism outcome pathophysiological mechanism Pathways poor prognosis pro-inflammatory cytokines Prognosis Prophylactic reported Respiratory system SARS-CoV-2 SARS-CoV-2 infected patients Thromboembolism thrombosis thrombotic thrombotic complication thrombotic event Treatment [DOI] 10.2147/JBM.S316014 PMC 바로가기 [Article Type] Review
Effect of Continuous Electrocardiogram Monitoring on Detection of Undiagnosed Atrial Fibrillation After Hospitalization for Cardiac Surgery A Randomized Clinical TrialResearch Published on 2021-08-272022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, [키워드] 12-lead electrocardiogram 24 hour 6 hour 95% CI absolute difference adverse outcomes after cardiac surgery age Analysis anticoagulation Atrial fibrillation benefit Can cardiac clinical conducted congestive heart failure Continuous continuous monitoring COVID-19 pandemic cumulative death defined detection determine diabetes discharge Effect electrocardiogram ENhance enrolled Enrollment female fibrillation finding Follow-up greater high risk hospital discharge Hospitalization hypertension Importance intent-to-treat intervention group investigator-initiated less major bleeding measure median MONITOR monitoring multicenter Myocardial infarction nervous system objective occurred Open-label participant Patient patients randomized persist Point postoperative primary end point Primary outcome randomization randomized clinical trial Registration Relevance Result risk factor Sample size secondary outcome setting Sex significant increase significantly stroke surgery surgical therapy Thromboembolism Trial usual care usual care group vascular disease women [DOI] 10.1001/jamanetworkopen.2021.21867 PMC 바로가기 [Article Type] Research
SARS-CoV-2 Antibody Isotypes in Systemic Lupus Erythematosus Patients Prior to Vaccination: Associations With Disease Activity, Antinuclear Antibodies, and Immunomodulatory Drugs During the First Year of the Pandemic예방 접종 전 전신 홍반성 루푸스 환자의 SARS-CoV-2 항체 아이소타입: 유행병 첫 해 동안 질병 활성, 항핵항체 및 면역조절 약물과의 연관성Immunology Published on 2021-08-272022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, [키워드] a minor Activation activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 albumin all subjects analyzed anti-dsDNA antibodies antibody antibody isotypes Antibody Response antinuclear antibodies antinuclear antibody Arthritis Blood Blood Group BMI Cell cell receptor collected complement Complement activation complement-immunological terms coronavirus coronavirus disease Coronavirus disease 2019 correlated Course COVID-19 COVID-19-related symptom dose drug Effects ELISA envelope protein exposure to Fever followed by glucocorticoid Hydroxychloroquine IgA IgG IgM Impact include individual Infection interferon investigated isotype longitudinal samples Lupus lupus (SLE) lupus erythematosus minor multiplex neutralization (effect of) neutralizing capacity objective pandemic Patient patients with SARS-CoV-2 PCR-confirmed progression proportion Proteins respiratory Result Rheumatic diseases rheumatologist risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection serological severe acute respiratory syndrome Coronavirus severe SARS severe SARS-CoV-2 SLE SLE patient smoking steroid Steroids subject Swedish Symptom systemic systemic lupus erythematosus the cell Thromboembolism type I interferon use of hydroxychloroquine vaccination were measured women Year [DOI] 10.3389/fimmu.2021.724047 PMC 바로가기 [Article Type] Immunology
Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series studyResearch Published on 2021-08-262022-10-28 Journal: The BMJ [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval Adults Analysis association BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccination BNT162b2 mRNA vaccine case sery ChAdOx1 nCoV-19 death Electronic health record England event first dose Health Service Hospital admission Hospital admissions incidence rate Increased increased risk ischaemic stroke Myocardial infarction National NHS objective office outcome outcome measure Oxford-AstraZeneca participant Pfizer-BioNTech positive Positive test Primary outcome Result risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test secondary setting Statistics subset Thromboembolic event Thromboembolism thrombosis thrombotic event Thrombotic events time interval vaccination Vaccine Vaccines Vascular venous Venous Thromboembolism [DOI] 10.1136/bmj.n1931 PMC 바로가기 [Article Type] Research
SELP Asp603Asn and severe thrombosis in COVID-19 malesSELP Asp603Asn 및 COVID-19 남성의 심각한 혈전증Letter to the Editor Published on 2021-08-162022-09-10 Journal: Journal of Hematology & Oncology [Category] MERS, SARS, 변종, [키워드] 95% CI Adhesion Molecule adjusted adjuvant therapy age androgen Androgen receptor Anti-selectin P monoclonal antibodies antibody Cell cell adhesion molecule coding variant Cohort confidence confidence interval COVID-19 D-dimer downregulated etiology Exome GEN-COVID homozygosity homozygote interval Logistic regression male Mortality Odds ratio Older P-selectin rationale receptor repurposing SARS-CoV-2 SELP Sequencing severity stratified by sex subject subjects supplementary material Testosterone the cell therapy Thromboembolism thrombosis thrombotic thrombotic risk Thrombus Venous Thromboembolism [DOI] 10.1186/s13045-021-01136-9 PMC 바로가기 [Article Type] Letter to the Editor