HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells
Resource and Technical Advance
[키워드] ACE2
ACE2 expression
AIDS/HIV
analyzed
antiviral genes
antiviral response
canonical
cause
change
chronic
controls
COVID-19
disease severity
downregulation
Enterocyte
epithelial cell
expression
fatality
GI Tract
Gut
highest
HIV infection
homeostasis
impair
increased risk
individual
individuals
infect
Innate immunity
interferon response
interferon signaling
intestinal
lymphoid
mucosal
Prevent
Protein
reduction
SARS-CoV-2
SARS-CoV-2 entry receptor
SARS-COV-2 infection
SARS-CoV-2 nucleocapsid
SARS-CoV-2 receptor
single-cell
small intestine
Symptoms
target cell
target cells
tissue
TMPRSS2
TMPRSS4
transcriptional profile
treated
uninfected
upregulation
vaccine response
[DOI] 10.1172/jci.insight.148920 PMC 바로가기 [Article Type] Resource and Technical Advance
[DOI] 10.1172/jci.insight.148920 PMC 바로가기 [Article Type] Resource and Technical Advance