Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial
우려되는 SARS-CoV-2 변이체에 대한 ChAdOx1 nCoV-19(AZD1222) 백신의 효능 202012/01(B.1.1.7): 무작위 대조 시험의 탐색적 분석
Clinical Trial
[키워드] 1:1
95% CI
adenoviral vector vaccine
Ageusia
analysed
Anosmia
assigned
AstraZeneca
AZD1222
B.1.1.7
B.1.1.7 lineage
B.1.1.7 variant
booster dose
booster doses
calculated
canonical
ChAdOx1
ChAdOx1 nCoV-19
Clinical research
Clinical vaccine efficacy
Coalition
collected
cough
COVID-19
COVID-19 disease
disease
dominant
Efficacy
efficacy analysis
efficacy cohort
enrolled
Exploratory analysis
female
Fever
finding
funding
Genomics
geometric mean
geometric mean ratio
groups
in vitro
Infection
Innovation
ISRCTN
Lineage
lineages
MenACWY
microneutralisation assay
NAAT
NAAT positive
NAAT positive swab
network
neutralisation activity
neutralising antibody response
Neutralising antibody responses
NIHR
NIHR Oxford Biomedical Research Centre
non-B.1.1.7 variant
nose and throat
nucleic acid
nucleic acid amplification
nucleic acid amplification test
Oxford
participant
phase 2/3
Poisson regression model
positive sample
post-hoc analysis
provided
randomised controlled trial
Randomly
receive
recruited
reduced
Registered
Relative risk
risk
robust
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 variant
second dose
second dose of vaccine
sequenced
seronegative participant
seronegative participants
Shortness of breath
South
Swab
swabs
symptomatic
symptomatic COVID-19
symptoms of COVID-19
tested
the vaccine
throat swabs
Trial
upper airway
upper airway swab
Vaccine
vaccine efficacy
vaccine-induced antibodies
vaccine-induced antibody
Valley
variant
variant of SARS-CoV-2
Victoria
Victoria lineage
virus neutralisation activity
were measured
[DOI] 10.1016/S0140-6736(21)00628-0 PMC 바로가기 [Article Type] Clinical Trial
[DOI] 10.1016/S0140-6736(21)00628-0 PMC 바로가기 [Article Type] Clinical Trial