COVID-19 precautionary behavior: the Israeli case in the initial stage of the outbreakResearch Article Published on 2020-11-162022-10-28 Journal: BMC Public Health [Category] COVID-19, [키워드] association calculated conducted COVID-19 COVID-19 outbreak cross-sectional emotional Emotional reactions ENhance females finding greater Hierarchical highest indicated initial interaction term knowledge Knowledge about COVID-19 measure moderate Older outbreak participant Participants Perceived susceptibility Precautionary behavior Questionnaires reaction Reactions Regression model response Result risk socio-demographic supplementary material susceptibility virus virus spread [DOI] 10.1186/s12889-020-09818-8 PMC 바로가기 [Article Type] Research Article
The Pivotal Role of Adipocyte-Na K peptide in Reversing Systemic Inflammation in Obesity and COVID-19 in the Development of Heart FailureReview Published on 2020-11-142022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] ACE-2 ACE-2 receptor Activation acute respiratory syndrome adipocyte adipocytes administration adverse outcome amplification amplify antioxidant Cell complex Concentration coronavirus coronavirus disease COVID COVID-19 Cytokine storm Cytokines Cytokines storm death degrade demonstrated development drug enzyme exacerbate Express expression failure fat form global pandemic group heart heart failure heme oxygenase increase infected with COVID-19 Infection Inflammatory cytokine Inflammatory mediators Laboratory Modification Na/K-ATPase obese obese patients obesity pandemic Patient peptide Proteins reactive oxygen species reactive oxygen specy receptor reduction regulate renal responsible risk RNA role ROS ROS production SARS-CoV-2 selective shown Signaling subjects subunit susceptibility systemic systemic cytokine systemic inflammation tissue virus white with COVID-19 [DOI] 10.3390/antiox9111129 PMC 바로가기 [Article Type] Review
Gender Disaggregation in COVID-19 and Increased Male SusceptibilityReview Published on 2020-11-132023-07-12 Journal: Journal of Nepal Health Research Council [Category] SARS, [키워드] COVID-19 Gender males sex disaggregation susceptibility [DOI] 10.33314/jnhrc.v18i3.3108 [Article Type] Review
Diesel Particulate Matter 2.5 Induces Epithelial-to-Mesenchymal Transition and Upregulation of SARS-CoV-2 Receptor during Human Pluripotent Stem Cell-Derived Alveolar Organoid DevelopmentArticle Published on 2020-11-132022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] accompanied Activation acute respiratory syndrome adverse effect AEC Affect alveolar alveolar organoid angiotensin-converting enzyme 2 Cell childhood clade cofactor coronavirus demonstrated development developmental dPM2.5 EMT epithelial Evidence explain exposure to expression Extracellular fibrosis had no Human human pluripotent stem cells in vitro incidence infancy Inflammation investigated lack lung Lung function matter mechanism multicellular nicotinamide adenine dinucleotide Organoid Particulate phosphate platform pluripotent stem cell prenatal promoted protease Protein provided pulmonary disease receptor reduced Research SARS-CoV-2 serine 2 Signaling significantly STEM susceptibility target cells Toxicity toxin transition transmembrane treated Treatment unique upregulated upregulation virus [DOI] 10.3390/ijerph17228410 PMC 바로가기 [Article Type] Article
Polymorphisms in Fc Gamma Receptors and Susceptibility to Malaria in an Endemic PopulationFc 감마 수용체의 다형성과 풍토병 집단에서의 말라리아 감수성Review Published on 2020-11-122024-08-11 Journal: Frontiers in immunology [Category] 말라리아, [키워드] Fc gamma receptors Immunoglobulin G malaria polymorphism susceptibility [DOI] 10.3389/fimmu.2020.561142 PMC 바로가기 [Article Type] Review
Association between Exposure to Influenza Vaccination and COVID-19 Diagnosis and OutcomesArticle Published on 2020-11-122022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI adjusted Affect age association case-negative study Clinical outcome confounding factors COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19 patients death exposure to expressed hazard ratio hospitalisation indicated Influenza influenza vaccine Italian not affect Odds ratio outbreak outcomes Patient positive positive individuals Prevalence Probability protective effect Rate receiving retrospective cohort study SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity SARS-CoV-2 test subjects susceptibility the SARS-CoV-2 vaccinated individual vaccination were assessed [DOI] 10.3390/vaccines8040675 PMC 바로가기 [Article Type] Article
Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study유전적 비만, 심혈관 대사 프로필 및 COVID-19 감수성에 대한 인과 추론: 멘델식 무작위 배정 연구Genetics Published on 2020-11-112022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 association BMI body mass body mass index cardiometabolic cardiometabolic trait cardiometabolic traits category Causal cholesterol co-morbidity Cohort conducted confidence interval coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 Host Genetics Initiative COVID-19 infection Cox model Cox proportional hazard models European evaluate Genetic genetic risk genetic risk score genetic risk scores Genotype Glucose glycated hemoglobin hazard ratio HDL-cholesterol hemoglobin high-density High-density lipoprotein higher odd higher odds Hospitalization host genetics increased risk independent dataset independent datasets indicated individual Inference integration LDL LDL cholesterol lipid profile lipoprotein low-density Low-density lipoprotein mendelian randomization Modification morbidities MR analysis multivariable logistic regression obesity observational studies observational study Odds ratio parameter participant phenotype positive predictor present produced profile Quantitative reported respiratory Result risk Risk assessment risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity serum severe acute respiratory syndrome Coronavirus Standard deviation Support susceptibility Systolic blood pressure tested traits Treatment Triglyceride triglycerides UK biobank Waist circumference was performed [DOI] 10.3389/fgene.2020.586308 PMC 바로가기 [Article Type] Genetics
Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibilityArticle Published on 2020-11-102022-10-04 Journal: Cell Discovery [Category] 변종, 유전자 메커니즘, 임상, 치료기술, [키워드] accounted Affect allele allele frequency Analysis association Asymptomatic Asymptomatic disease bioinformatics Chinese Chinese patient complex diseases conducted confounding factors COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 severity Critical Critically ill death disease severity DPP7 effort FIVE General population Genetic genetic architecture genetic study genetic variants Genome-wide association studies genomic GOLGA3 group help Host IL-1 ill patient Infection initial Interaction International involved Laboratory limitation locus loss of function manifestation Mechanisms of disease Mild missense variant moderate outbreak outcome Patient patients phenotypic provide Sequencing Severe patient severity Shenzhen signaling pathway significantly stability suggested susceptibility TMPRSS2 protein Variability variant whole-genome sequencing [DOI] 10.1038/s41421-020-00231-4 PMC 바로가기 [Article Type] Article
Genomics in the era of COVID-19: ethical implications for clinical practice and public healthComment Published on 2020-11-092022-10-31 Journal: Genome Medicine [Category] COVID-19, SARS, [키워드] Clinical practice COVID-19 disease severity Ethics Factor Genomics highlight Host Host genomics implication patients with COVID-19 potential benefit public health susceptibility Variability [DOI] 10.1186/s13073-020-00792-9 PMC 바로가기 [Article Type] Comment
Immunomodulation for Severe COVID-19 Pneumonia: The State of the ArtImmunology Published on 2020-11-092022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] accounted acute respiratory distress acute respiratory syndrome antagonistic anti-inflammatory cytokine anti-inflammatory response anti-SARS-CoV-2 cause caused coronavirus Coronavirus disease 2019 Course COVID-19 Critical illness Critically ill patient deaths Disease progression early stage Evidence immune immune response Immune status immunomodulation Immunopathogenesis immunosuppressive Immunotherapy implication Increasing infections Inflammatory cytokine storm late stage multiple organ dysfunction multiple organ failure Novel coronavirus Pathogenesis Patient Pneumonia SARS-CoV-2 secondary infections severe acute respiratory syndrome coronavirus 2 severe COVID-19 severe disease state suggested susceptibility syndrome systemic inflammatory response the disease therapy with COVID-19 worldwide pandemic [DOI] 10.3389/fimmu.2020.577442 PMC 바로가기 [Article Type] Immunology