COVID-19: Rational discovery of the therapeutic potential of Melatonin as a SARS-CoV-2 main Protease Inhibitor
Research Paper
[키워드] ACE-2
addition
angiotensin-converting enzyme 2
Anti-inflammatory
antiviral activity
binding site
carried
Cell
clinical trials
complexes
Compound
conserved
coronavirus
COVID-19
described
disease
disorder
docking
docking study
early stage
Effect
Efficacy
enzyme
evaluated
globe
hospital
hyper-inflammation
identify
immunomodulatory
in silico
inhibitor
inhibitors
Interaction
Ligand
maintain
melatonin
Molecular docking study
mortality rate
MPro
oxidative stress
pandemic
PDB
pharmacological
Protein Data Bank
raised
rational design
reduce
SARS-CoV-2
SARS-CoV-2 main protease
Sepsis
similarity
Spread
Stage
the cytokine storm
the disease
therapeutic potential
Treatment
WHO
World Health Organization
[DOI] 10.7150/ijms.48053 PMC 바로가기 [Article Type] Research Paper
[DOI] 10.7150/ijms.48053 PMC 바로가기 [Article Type] Research Paper