Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy이탈리아 가정의 고양이와 개에서 SARS-CoV-2에 노출되었다는 증거Article Published on 2020-12-042022-09-12 Journal: Nature Communications [Category] MERS, 진단, 치료기술, [키워드] animals Antibody titers cats condition COVID-19 COVID-19 negative evidence of ferret ferrets Households human infection Humoral immunity infect Infection Italy Neutralizing antibodies neutralizing antibody titers PCR positive positive question raise risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibody significantly more susceptibility tested transmitted understanding urgent investigation [DOI] 10.1038/s41467-020-20097-0 PMC 바로가기 [Article Type] Article
Development of SARS-CoV-2 vaccines: challenges, risks, and the way forwardReview Published on 2020-12-032023-06-15 Journal: Human vaccines & immunotherapeutics [Category] MERS, [키워드] Antibody-dependent enhancement immune responses Neutralizing antibodies SARS-CoV-2 vaccines Vaccine development [DOI] 10.1080/21645515.2020.1845524 PMC 바로가기 [Article Type] Review
Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infectionSARS-CoV-2 감염 후 중화 항체 및 T 세포 반응의 내구성Article Published on 2020-12-012022-09-11 Journal: Frontiers of medicine [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive Adaptive immunity anti-SARS-CoV-2 blood sample Blood samples caused CD4 CD8 Cell collected convalescent coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 patient Critical Diagnosis Efficacy ELISA examined IgG IgG antibodies IgG antibody IgGs Immunity Infection interferon investigated memory N-protein Neutralizing activity Neutralizing antibodies neutralizing antibody no difference offer pandemic positive Post-infection predominant Probability pseudovirus respiratory SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection serum severe acute respiratory syndrome Coronavirus specimen T-cell T-cell Response triggered vaccination Vaccine variant variant of SARS-CoV-2 variants of SARS-CoV-2 [DOI] 10.1007/s11684-020-0822-5 PMC 바로가기 [Article Type] Article
Long-Term Existence of SARS-CoV-2 in COVID-19 Patients: Host Immunity, Viral Virulence, and TransmissibilityCOVID-19 환자에서 SARS-CoV-2의 장기 존재: 숙주 면역, 바이러스 독성 및 전염성Article Published on 2020-12-012022-09-11 Journal: Virologica Sinica [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] antibody CD4 CD8 Cell cell supernatant cell supernatants Clinical characteristics clinically coding regions Cohort collected COVID-19 COVID-19 patient cured Cytopathic effect demographic demographic data detectable Existence favor Genome sequencing IFN-γ IgG initial symptom initial symptoms inoculated interferon gamma long-term lymphocyte Lymphocyte functionality Lymphocytes median median age Mild Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples neutralisation Neutralization antibody Neutralizing activity Neutralizing antibodies neutralizing antibody NK cell NK cells nucleic acid test passages pathogenicity Patient patients peripheral positive positively correlated SARS-CoV-2 SARS-CoV-2 clearance SARS-COV-2 infection SARS-CoV-2 nucleic acid SARS-CoV-2 virus Sequencing Spike protein synonymous variant Vero E6 Vero E6 cell VERO E6 cells Viral viral clearance Viral load viral pathogenicity [DOI] 10.1007/s12250-020-00308-0 PMC 바로가기 [Article Type] Article
[Immunity against SARS-CoV-2: walking to the vaccination][SARS-CoV-2에 대한 면역: 예방 접종을 위해 도보]Review Published on 2020-12-012022-09-11 Journal: Revista española de quimioterapia : publicación [Category] MERS, SARS, 임상, 진단, 치료법, [키워드] acquisition assumed Betacoronavirus cellular clinical evaluation Coronaviridae coronavirus COVID-19 CoVs Dada English envelope family Coronaviridae Fatality rate genus Betacoronavirus herd immunity humoral immune response Immunity immunization life mass immunization measure membrane natural infection Neutralizing antibodies neutralizing antibody nucleic acid nucleocapsid peptide peptides Protein required S antigen sarbecovirus SARS-CoV-2 SARS-CoV2 Spain Spanish structural protein structural proteins subgenus the SARS-CoV-2 vaccination Vaccine Viral viral vectors virus viruses [DOI] 10.37201/req/086.2020 PMC 바로가기 [Article Type] Review
The kinetics of viral load and antibodies to SARS-CoV-2Article Published on 2020-12-012023-06-19 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, [키워드] COVID-19 IgA IgG IgM Neutralizing antibodies SARS-CoV-2 Viral load [DOI] 10.1016/j.cmi.2020.08.043 PMC 바로가기
Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization회복기 혈장 항-SARS-CoV-2 스파이크 단백질 엑토도메인 및 수용체 결합 도메인 IgG는 바이러스 중화와 상관관계가 있습니다Clinical Trial Published on 2020-12-012022-09-11 Journal: The Journal of Clinical Investigation [Category] MERS, SARS, 비임상, 임상, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immunity anti-RBD anti-receptor-binding domain anti-SARS-CoV-2 Anti-spike Asymptomatic breath Cellular immune response convalescent plasma convalescent plasma samples coronavirus COVID-19 COVID-19 disease COVID-19 treatment Critical decrease detect disease severity domain donors Dyspnea ectodomain highlight Hospitalization identify IgG IgG titer IgG titers immune immunology in vitro In vitro assay individual Infectious disease information Molecular pathology neutralization Neutralizing antibodies pathology patients with COVID-19 plasma positive correlation Probability Protective respiratory SARS-CoV-2 SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus significantly Spike protein surrogate titers Treatment Virus neutralization [DOI] 10.1172/JCI141206 PMC 바로가기 [Article Type] Clinical Trial
Association between SARS-CoV-2 Neutralizing Antibodies and Commercial Serological AssaysArticle Published on 2020-12-012023-06-19 Journal: Clinical Chemistry [Category] MERS, SARS, [키워드] COVID-19 Neutralizing antibodies SARS-CoV-2 serology [DOI] 10.1093/clinchem/hvaa211 PMC 바로가기
Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platformArticle Published on 2020-11-302022-10-29 Journal: Nature Communications [Category] COVID-19, SARS, [키워드] Antigen Cancer caused cellular immune responses Coronavirus-2 develop development DNA expressing generate global pandemic humoral immunized immunodominant implicated Infectious disease Live attenuated vaccines mice Neutralizing antibodies nucleocapsid antigen nucleocapsid antigens platform poxvirus protective immunity robust SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 vaccine stimulate unique Vaccine vaccine candidate vaccine platform vaccinia vector viral infection [DOI] 10.1038/s41467-020-19819-1 PMC 바로가기 [Article Type] Article
Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidateReport Published on 2020-11-272022-10-28 Journal: Science (New York, N.y.) [Category] COVID-19, [키워드] acute respiratory syndrome Analysis complexes coronavirus coronavirus disease COVID-19 ectodomain effort full-length full-length SARS-CoV-2 full-length spike protein host immune system immune response Interaction Microscopy Modification Neutralizing antibodies Novavax pandemic performed prefusion conformation provide responsible reveal SARS-CoV-2 SARS-CoV-2 spike glycoprotein Science Spike protein spike trimers stability Structure structures subunit the S1 subunit the vaccine Trimeric spike protein Vaccine vaccine candidate Vaccine development virus [DOI] 10.1126/science.abe1502 PMC 바로가기 [Article Type] Report