Policy options for deploying anti-malarial drugs in endemic countries: a population genetics approach말라리아 유행 국가에서 항말라리아 약물 배포를 위한 정책 옵션: 인구 유전학적 접근Research Published on 2012-12-172024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] adherence drugs malaria Plasmodium falciparum Policy resistance Treatment [DOI] 10.1186/1475-2875-11-422 PMC 바로가기 [Article Type] Research
Scaling-up malaria treatment: a review of the performance of different providers말라리아 치료 확대: 다양한 제공자의 성과에 대한 검토Research Published on 2012-12-122024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Act community health workers malaria private sector public sector Treatment [DOI] 10.1186/1475-2875-11-414 PMC 바로가기 [Article Type] Research
Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly NeutralizingResearch Article Published on 2012-11-212022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Amgen antibody binding conserved convalescent patient different ectodomain effective expressing glycoprotein Human Human monoclonal antibody immune implication Infected isolates monoclonal antibody neutralize Neutralizing Patient produced Pseudotyped virus Receptor binding domain Region respiratory S protein S1 domain S2 domain SARS-CoV SARS-CoV spike sequence sera severe shown Subunit vaccine the S protein therapeutic therapy Treatment variant viruses [DOI] 10.1371/journal.pone.0050366 PMC 바로가기 [Article Type] Research Article
Scale-up of home-based management of malaria based on rapid diagnostic tests and artemisinin-based combination therapy in a resource-poor country: results in Senegal자원 부족 국가에서 신속 진단 검사와 아르테미시닌 기반 복합 요법에 기반한 가정 기반 말라리아 관리의 확대: 세네갈에서의 결과Research Published on 2012-09-252024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Community Diagnosis Home-based management malaria Treatment [DOI] 10.1186/1475-2875-11-334 PMC 바로가기 [Article Type] Research
In vitro inhibition of transmissible gastroenteritis coronavirus replication in swine testicular cells by short hairpin RNAs targeting the ORF 7 geneResearch Published on 2012-08-282022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] Apoptosis approach assays Cell cell proliferation characterized contagious Coronavirus replication Cytopathic effect demonstrated diarrhea effective Efficiency Evidence examined expressing expression expression plasmid expression plasmids gastroenteritis Genome high mortality in vitro indicated Infection inhibit inhibited inhibitory effect N gene ORF ORF 7 Quantitative Replication reporter Result RNA RNA interference RT-PCR analysis selected sequence short hairpin RNA shown significantly specificity STABLE target gene TCID TGEV the vaccine therapeutic transmissible gastroenteritis virus Treatment viral disease viral infections viral replication virus virus replication virus titer vomiting [DOI] 10.1186/1743-422X-9-176 PMC 바로가기 [Article Type] Research
Concise Definitive Review: InfluenzaArticle Published on 2012-08-072023-05-31 Journal: Critical Care Medicine [Category] Fulltext, 조류인플루엔자, [키워드] Avian flu complications Influenza pandemic Pneumonia Treatment [DOI] 10.1097/CCM.0b013e318180b039 PMC 바로가기 [Article Type] Article
Detection of human coronavirus strain HKU1 in a 2 years old girl with asthma exacerbation caused by acute pharyngitisCase Report Published on 2012-08-032022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] association Asthma asthmatic caused coronavirus detection healthy HKU1 Infection molecular morbidity respiratory respiratory viral infection Seven Treatment viral infection [DOI] 10.1186/1743-422X-9-142 PMC 바로가기 [Article Type] Case Report
Clinical features of the hospitalized patients with 2009 pandemic influenza A (H1N1) in Santa Fe, ArgentinaArticle Published on 2012-07-232023-06-23 Journal: Influenza and Other Respiratory Viruses [Category] 신종인플루엔자, [키워드] Clinical features fatal cases Hospitalized influenza A (H1N1)pdm2009 Treatment [DOI] 10.1111/j.1750-2659.2012.00405.x PMC 바로가기
Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection작은 분자에 의한 숙주 면역 방어의 자극은 세균 감염으로부터 C. elegans를 보호합니다Research Article Published on 2012-06-142022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect Analysis antibiotic Antibiotics ATF-7 Author Bacterial Bacterial infection Bacterial infections bacterial pathogen Bacterial pathogens Caenorhabditis elegan Caenorhabditis elegans cellular processe cellular processes Compound conserved effector molecule Efficacy elegan expression Gene Genes growth Host immune response host immunity identify immune immune regulators immunostimulatory Infection Interaction low molecular weight mechanism mechanism of action mode molecule molecules mutants nematode offer Pathogens pathway promote PROTECT Pseudomonas aeruginosa required small molecule Small molecules stimulate Stimulation tested therapy These data Transcription transcription factor Transcriptome Treatment variety [DOI] 10.1371/journal.pgen.1002733 PMC 바로가기 [Article Type] Research Article
CD200 Receptor Controls Sex-Specific TLR7 Responses to Viral InfectionResearch Article Published on 2012-05-172022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] absence Activation administration anti-viral response Author blocker Cancer CD200 clearance clinical trial Control dependent on determine determined different disease disease symptom ENhance Factor female female patient females Host humans Hypothesis IFN immune immune inhibitory immune response immune system immunological impair implication IMPROVE in vitro in vivo Infection influenza A virus Influenza virus inhibit inhibitory inhibitory signal lack Ligand lung MHV mice microbial infection mouse hepatitis neutrophil observé outcome overactive pathogen pathology pathway predict Prevent provided receptor receptors Release reported response Sex Sex difference Signaling supported suppresse therapeutic targeting therapeutic use threshold TLR7 Treatment Type I IFN type I interferon viral clearance viral infection virus virus infection [DOI] 10.1371/journal.ppat.1002710 PMC 바로가기 [Article Type] Research Article